1,2,4-Trihydroxyanthraquinone;purpurin
Use Of Purpurin
Purpurin is a natural anthraquinone compound from Rubia tinctorum L. Purpurin has antidepressant like effects.
Name Of Purpurin
English Name: purpurin
Chinese Alias:
Violin | 1,2,4-trihydroxyanthraquinone | hydroxyalizarin | 1,2,4-trihydroxyanthraquinone | Red Violin / 1,2,4-trihydroxyanthraquinone | Red Violin
Bioactivity Of Purpurin
Description: purpurin is a natural anthraquinone compound from Rubia tinctorum L. Purpurin has antidepressant like effects.
Related Categories: signal path > > other > > other
Research Field > > neurological diseases
In Vivo Study: the effect of purpurin (oral; 2,6,18mg / kg, 3 weeks) on adult male C57BL / 6J mice (6-7 weeks) Week old) behavior and stress axis reactivity produce dose-dependent antidepressant like effects [1].
References: [1] Ma L, et al. Purpurin exerted antidepressant-like effects on behavior and stress axis reactivity: evidence of serotonergic engagement. Psychopharmacology (Berl). 2020 Mar; 237(3):887-899.
Physicochemical Properties Of Purpurin
Density: 1.7 ± 0.1 g / cm3
Boiling Point: 525.1 ± 45.0 ° C at 760 mmHg
Melting Point: 253-256 º C (lit.)
Molecular Formula: c14h8o5
Molecular Weight: 256.210
Flash Point: 285.4 ± 25.2 ° C
Accurate Mass: 256.037170
PSA:94.83000
LogP:4.60
Appearance: Powder
Steam Pressure: 0.0 ± 1.4 mmHg at 25 ° C
Refractive Index: 1.773
Storage Conditions: This product should be sealed in a dry and dark place for storage.
Molecular Structure
1. Molar refractive index: 64.31
2. Molar volume (m3 / mol): 154.3
3. Isotonic specific volume (90.2k): 480.4
4. Surface tension (dyne / cm): 93.9
5. Polarizability (10-24cm3): 25.49
Purpurin safety information
Signal Word: warning
Hazard Statement: h315-h319-h335
Warning Statement: p261-p305 + P351 + P338
Personal Protective Equipment: dust mask type N95 (US); Eyeshields; Gloves
Hazard Code (Europe): Xi: iritant;
Risk Statement (Europe): R36 / 37 / 38
Safety Statement (Europe): S26; S36
Transport Code of dangerous goods: nonh for all modes of transport
Wgk Germany: 3
RTECS No.: cb8200000
Customs Code: 2914690090
Purpurin Customs
Customs Code: 2914690090
Chinese overview: 2914690090 other quinones Value added tax rate: 17.0%, tax rebate rate: 9.0%, regulatory conditions: no MFN tariff: 5.5%, ordinary tariff: 30.0%
Summary:2914690090 other quinones。 Supervision conditions:None。 VAT:17.0%。 Tax rebate rate:9.0%。 MFN tariff:5.5%。 General tariff:30.0%
Literature
Structural and optical properties of Purpurin for dye-sensitized solar cells.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 149 , 997-1008, (2015)
In this work, we reported a combined experimental and theoretical study on molecular structure, vibrational spectra and Homo-Lumo analysis of Purpurin and TiO2/Purpurin. The geometries, electronic str...
Protection against the bacterial mutagenicity of heterocyclic amines by purpurin, a natural anthraquinone pigment.
Mutat. Res. 444(2) , 451-61, (1999)
Purpurin (1,2,4-trihydroxy-9,10-anthraquinone) is a naturally occurring anthraquinone pigment found in species of madder root. We have found that the presence of purpurin in bacterial mutagenicity ass...
Toxicity and tumorigenicity of purpurin, a natural hydroxanthraquinone in rats: induction of bladder neoplasms.
Cancer Lett. 102(1-2) , 193-8, (1996)
Chronic toxicity and tumorigenicity of purpurin, a natural hydroxyanthraquinone, was examined in two groups of male F344 rats. One group was given a basal diet mixed with purpurin at a concentration o...
Englisah Alias Of Purpurin
EINECS 201-359-8
Verantin
Purpurin
1,2,4-Trihydroxy-9,10-anthracenedione
I. Natural Red 16
natural red 161,2,4-Trihydroxy-9,10-anthraquinone
9,10-Anthracenedione, 1,2,4-trihydroxy-
Purpurine
C.I. Natural Red 8
1,2,4-trihydroxyanthracene-9,10-dione
1,2,4-trishydroxy-9,10-anthraquinone
1,2,4-Trihydroxyanthraquinone
Smoke Brown G
MFCD00001203
Hydroxylizaric acid
