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Benzoylpaeoniflorin

Short Description:

Application of Benzoyl paeoniflorin

Benzoylpaeoniflorin is a natural compound. It is reported that it may treat coronary heart disease by reducing apoptosis.


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Product Specification

Common Name: benzoyl paeoniflorin

CAS No.: 38642-49-8

English Name: benzoylpaeoniflorin

Molecular Weight: 584.568

Density: 1.6 ± 0.1 g / cm3 boiling point: 742.9 ± 60.0 ° C at 760 mmHg

Molecular formula: c30h32o12 melting point: n / A

MSDS: n / a flash point: 243.1 ± 26.4 ° C

Biological Activity Of Benzoyl paeoniflorin

Description: benzoylpaeoniflorin is a natural compound, which is reported to treat coronary heart disease by reducing apoptosis.

Related Categories: signal path > > other > > other

Natural Products > > terpenoids and glycosides

Research field > > cardiovascular disease

Reference: [1]. Xinfeng Zhao, et al. Quantitative and Qualitative Determination of Liuwei Dihuang Tablets by HPLC–UV-MS–MS. Journal of Chromatographic Science, Vol. 45, September 2007, 549-552

[2]. ZHANG Er-li, et al. Effects of Benzoylpaeoniflorin on apoptosis of Rats with Coronary Heart Diseases. Chinese Journal of Laboratory Diagnosis, 2011-04.

Physicochemical properties of benzoyl paeoniflorin

Density: 1.6 ± 0.1 g / cm3

Boiling Point: 742.9 ± 60.0 ° C at 760 mmHg
Molecular Formula: C30H32O12

Molecular Weight: 584.568
Flash Point: 243.1 ± 26.4 °

Caccurate Mass: 584.189392

PSA:170.44000 LogP:5.55

Vapor pressure: 0.0 ± 2.6 mmHg at 25 ° C
Refractive Index: 1.682

English Alias Of Benzoylpaeoniflorin

{(3S,5R,6S)-1-({[(4,5-Dihydroxy-2-cyclohexen-1-yl)carbonyl]oxy}methyl)-3-[(1aR)-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yloxy]-5,6-dihydroxy-4-methyl-2-oxabicyclo[2.2.1]hept-3-yl}methyl benzoate

2-Cyclohexene-1-carboxylic acid, 4,5-dihydroxy-, [(3S,5R,6S)-3-[(benzoyloxy)methyl]-3-[(1aR)-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yloxy]-5,6-dihydroxy-4-methyl-2-oxabicyclo[2.2.1]hept-1-yl]methyl ester

β-D-Glucopyranoside,(1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-benzoate

{(1R,2S,3R,5R,6R,8S)-3-[(6-O-Benzoyl-β-D-glucopyranosyl)oxy]-6-hydroxy-8-methyl-9,10-dioxatetracyclo[4.3.1.0.0]dec-2-yl}methyl benzoate

Jiangsu Yongjian Pharmaceutical Technology Co., Ltd

Jiangsu Yongjian Pharmaceutical Technology Co., Ltd., established in March 2012, is a high-tech enterprise integrating R & D, production and sales. It is mainly engaged in the production, customization and production process development of active components of natural products, traditional Chinese medicine reference materials and drug impurities. The company is located in China Pharmaceutical City, Taizhou City, Jiangsu Province, including a 5000 square meter production base and a 2000 square meter R & D base. It mainly serves major scientific research institutes, universities and decoction piece production enterprises across the country.

So far, we have developed more than 1500 kinds of natural compound reagents, and compared and calibrated more than 300 kinds of reference materials, which can fully meet the daily inspection needs of major scientific research institutes, university laboratories and decoction pieces production enterprises.

Based on the principle of good faith, the company hopes to sincerely cooperate with our customers. Our aim is to serve the modernization of traditional Chinese medicine.

Advantageous business scope of the company

1.R & D and sales of traditional Chinese medicine and chemical control products;

2.Customized traditional Chinese medicine monomer compounds according to customer characteristics

3.Research on quality standard and process development of traditional Chinese medicine (plant) extract

4. Technology cooperation, transfer and new drug research and development.

Customized service of chemical reference materials of traditional Chinese Medicine

Jiangsu Yongjian Pharmaceutical Technology Co., Ltd. is mainly engaged in the basic research of active substances of traditional Chinese medicine for more than ten years. So far, the company has conducted in-depth research on more than 100 kinds of commonly used traditional Chinese medicine, and extracted thousands of chemical components.

The company has top R & D personnel and perfect testing and analysis equipment in the industry, and has served hundreds of scientific research institutions. It can quickly and efficiently meet the needs of customers.

Drug Impurity Separation, Preparation And Structure Confirmation Service

Impurities in drugs are closely related to the quality, safety and stability of drugs. The preparation and structure confirmation of impurities in drugs can help us understand the ways of impurities and provide a basis for the improvement of production process. Therefore, the preparation and separation of impurities is of great significance to drug research and development.

However, the content of impurities in the drug is low, the source is wide, and the structure is mostly similar to the principal component. What technology can be used to separate and purify all impurities in the drug one by one and quickly? What techniques and methods are used to confirm the structure of these impurities? This is the difficulty and challenge faced by many pharmaceutical units, especially the pharmaceutical enterprises of plant medicine and Chinese patent medicine.

Based on such needs, the company has launched drug impurity separation and purification services. Relying on nuclear magnetic resonance, mass spectrometry and other equipment and technologies, the company can quickly identify the structure of the separated compounds, so as to meet the needs of customers.

SPF Animal Experiment

The construction area of the animal experimental area is 1500 square meters, including 400 square meters of SPF level experimental area and 100 square meters of P2 level cell laboratory. Led by scientists of China Pharmaceutical University, it forms a core technical team with a number of returnees. Provide high-quality animal models, experimental design, overall projects and other services for biomedical scientific research, teaching and industrial development.

Scope Of Business:

1. Small animal feeding

2. Animal disease modeling

3. College project outsourcing

4. Pharmacodynamic evaluation in vivo

5. Pharmacokinetic evaluation

6. Tumor cell experiment service

Our Strengths:

1. Focus on real experiments

2. Strictly standardize the process

3. Strictly sign confidentiality agreement

4. Own laboratory without intermediate links

5. The professional technical team guarantees the experimental quality

SPF experimental environment, specially assigned person feeding, real-time tracking experimental progress


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