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China Gold Supplier for Atractylodin - Dimethylfraxetin ;6,7,8-Trimethoxycoumarin – Yongjian

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China Gold Supplier for Atractylodin - Dimethylfraxetin ;6,7,8-Trimethoxycoumarin – Yongjian Detail:

Product Specification

Common Name: ash tree element
CAS No.: 6035-49-0
Density: 1.2 ± 0.1 g / cm3
Molecular Formula: C12H12O5
MSDS: N / A

English Name: dimethylfraxetin
Molecular Weight: 236.221
Boiling Point: 408.0 ± 45.0 ° C at 760 mmHg
Melting Point: 104-105 º C
Flash Point: 184.3 ± 28.8 ° C

Biological activity of dimethylfraxetin

Description: dimethylfraxetin is a carbonic anhydrase inhibitor with a Ki value of 0.0097 μ M。

Related Categories:
signal pathway > > metabolic enzyme / protease > > carbonic anhydrase

Research field > > cancer

Natural Products > > benzoic acids

Target: ki: 0.0097 μ M (Carbonic anhydrase)[1]

In vitro study: in CA I, one prominent compound is dimethylfluoxetine (compound 17), a nanomolar CA I inhibitor. This trimethoxycoumarin is the most effective of any NP coumarin among the six CA isozymes in this study [1].
Kinase: before determination, the inhibitor (including dimethylerythromycin) and the enzyme solution were pre incubated at room temperature for 6 hours to allow the formation of enzyme inhibitor complex [1]

References: [1]  Davis RA, et al. Natural product coumarins that inhibit human carbonic anhydrases. Bioorg Med Chem. 2013 Mar 15; 21(6):1539-43.

Dimethylfraxetin

Density: 1.2 ± 0.1 g / cm3
Boiling Point: 408.0 ± 45.0 ° C at 760 mmHg
Melting Point: 104-105 º C
Molecular Formula: c12h12o5
Molecular Weight: 236.221
Flash Point: 184.3 ± 28.8 ° C
Accurate Mass: 236.068466
PSA:57.90000
LogP:1.75
Steam Pressure: 0.0 ± 1.0 mmHg at 25 ° C
Refractive index: 1.545

Dimethylfraxetin Safety Information

Risk statement (Europe): 22
Safety statement (Europe): 22-45
Customs Code: 293220990

Dimethylfraxetin Upstream And Downstream Products

DDimethylfraxetin Upstream Products

CAS 186581-53-3 Diazomethane
CAS No. 486-21-5 Isozinpidine
CAS 107078-01-3 6-hydroxy-7,8-d…
CAS No. 77-78-1 Dimethyl sulfate
DDimethylfraxetin Downstream Products
CAS No.72023-44-0 2,3,4,5-tetrame…

Dimethylfraxetin Customs

Customs Code: 293220990
Chinese overview: 293220990 Other lactones VAT rate: 17.0% Tax rebate rate: 13.0% Regulatory conditions: none MFN tariff: 6.5% General tariff: 20.0%
Declaration elements: product name, composition, content and purpose
Summary:2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

English Alias Of Dimethylfraxetin

6,7,8-trimethoxychromen-2-one
6,7,8-Trimethoxy-2H-chromen-2-one
2H-1-Benzopyran-2-one, 6,7,8-trimethoxy-


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China Gold Supplier for Atractylodin - Dimethylfraxetin ;6,7,8-Trimethoxycoumarin –  Yongjian detail pictures


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Our pursuit and corporation aim should be to "Always satisfy our consumer requirements". We carry on to build and style and design remarkable quality items for both our outdated and new clients and reach a win-win prospect for our clients at the same time as us for China Gold Supplier for Atractylodin - Dimethylfraxetin ;6,7,8-Trimethoxycoumarin – Yongjian , The product will supply to all over the world, such as: Brisbane, Manchester, Germany, We have exported our products all over the world, especially the USA and European countries. Furthermore, all of our products are manufactured with advanced equipment and strict QC procedures to ensure high quality.If you are interested in any of our products, please don't hesitate to contact us. We will try our best to meet your needs.
  • This supplier offers high quality but low price products, it is really a nice manufacturer and business partner.
    5 Stars By Judy from Islamabad - 2018.09.16 11:31
    The factory workers have a good team spirit, so we received high quality products fast, in addition, the price is also appropriate, this is a very good and reliable Chinese manufacturers.
    5 Stars By Ina from Greek - 2018.09.08 17:09
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