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China Gold Supplier for Cas No.3681-93-4 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian

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China Gold Supplier for Cas No.3681-93-4 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian Detail:

Essential Information

CAS No.: 524-30-1 [1]

EINECS No.: 208-355-5

Molecular Formula: c16h18o10

Molecular Weight: 370.3081

Molecular Structure: (Figure 1)

Properties: Light yellow acicular crystal or flake crystal.

Density: 1.634g/cm3

Boiling Point: 722.2 ° C at 760 mmHg

Flash Point: 267 ° C

Steam Pressure: 6.87e-22mmhg at 25 ° C

Bioactivity of Fraxin

Description: Fraxin can be isolated from Acer tegmentosum, F. ornus and a. hippocastanum. It is a glycoside of fraxine [1] and has antioxidant, anti-inflammatory and anti metastasis activities. Fraxin exhibits antioxidant activity by inhibiting cyclic adenylate phosphodiesterase [2].

Target: cyclo AMP phosphodiesterase enzyme [2]

In Vitro Study: Fraxin (100 μ M) It has no cytotoxicity to Hep G2 cells. Fraxin at non cytotoxic concentrations significantly reduced t-BHP induced ROS production in a dose-dependent manner [1]. Fraxin (0.5 mm) can scavenge free radicals at high concentration and has cytoprotective effect on H2O2 mediated oxidative stress [2].

In vivo study: Fraxin (50 mg / kg, PO) significantly blocked CCl4 induced elevation of ALT and AST. Fraxin (10 and 50 mg / kg, PO) significantly reduced GSSG levels (1.7 ± 0.3 and 1.5 ± 0.2 nm / g liver, respectively) compared with GSSG levels in the CCl4 treated group

Reference:. Fraxin (50 mg/kg, p.o.) significantly blocks the CCl4-induced elevation of ALT and AST. Fraxin (10 and 50 mg/kg, p.o.) significantly reduces the GSSG levels (1.7±0.3 and 1.5±0.2 nM/g liver, respectively) compared with the GSSG levels of the CCl4-treated group[1].

[2]. Whang WK, et al. Natural compounds,fraxin and chemicals structurally related to fraxin protect cells from oxidative stress. Exp Mol Med. 2005 Oct 31;37(5):436-46.


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China Gold Supplier for Cas No.3681-93-4 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1  –  Yongjian detail pictures

China Gold Supplier for Cas No.3681-93-4 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1  –  Yongjian detail pictures


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continue to enhance, to be certain solution top quality in line with market and buyer standard requirements. Our corporation has a excellent assurance program are actually established for China Gold Supplier for Cas No.3681-93-4 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian , The product will supply to all over the world, such as: Nicaragua, United Arab emirates, Tajikistan, We supply professional service, prompt reply, timely delivery, excellent quality and best price to our customers. Satisfaction and good credit to every customer is our priority. We focus on every detail of order processing for customers till they have received safe and sound products with good logistics service and economical cost. Depending on this, our products are sold very well in the countries in Africa, the Mid-East and Southeast Asia. Adhering to the business philosophy of ‘customer first, forge ahead', we sincerely welcome clients from at home and abroad to cooperate with us.
  • We are old friends, the company's product quality has been always very good and this time the price is also very cheap.
    5 Stars By Helen from Jeddah - 2018.11.06 10:04
    The company has rich resources, advanced machinery, experienced workers and excellent services, hope you keep improving and perfecting your products and service, wish you better!
    5 Stars By Evangeline from Vancouver - 2017.04.18 16:45
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