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Chinese wholesale Alashinol G，(-)-carinol - Dimethylfraxetin ;6,7,8-Trimethoxycoumarin – Yongjian Featured Image
  • Chinese wholesale Alashinol G，(-)-carinol - Dimethylfraxetin ;6,7,8-Trimethoxycoumarin – Yongjian

Chinese wholesale Alashinol G，(-)-carinol - Dimethylfraxetin ;6,7,8-Trimethoxycoumarin – Yongjian

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Chinese wholesale Alashinol G，(-)-carinol - Dimethylfraxetin ;6,7,8-Trimethoxycoumarin – Yongjian Detail:

Product Specification

Common Name: ash tree element
CAS No.: 6035-49-0
Density: 1.2 ± 0.1 g / cm3
Molecular Formula: C12H12O5
MSDS: N / A

English Name: dimethylfraxetin
Molecular Weight: 236.221
Boiling Point: 408.0 ± 45.0 ° C at 760 mmHg
Melting Point: 104-105 º C
Flash Point: 184.3 ± 28.8 ° C

Biological activity of dimethylfraxetin

Description: dimethylfraxetin is a carbonic anhydrase inhibitor with a Ki value of 0.0097 μ M。

Related Categories:
signal pathway > > metabolic enzyme / protease > > carbonic anhydrase

Research field > > cancer

Natural Products > > benzoic acids

Target: ki: 0.0097 μ M (Carbonic anhydrase)[1]

In vitro study: in CA I, one prominent compound is dimethylfluoxetine (compound 17), a nanomolar CA I inhibitor. This trimethoxycoumarin is the most effective of any NP coumarin among the six CA isozymes in this study [1].
Kinase: before determination, the inhibitor (including dimethylerythromycin) and the enzyme solution were pre incubated at room temperature for 6 hours to allow the formation of enzyme inhibitor complex [1]

References: [1]  Davis RA, et al. Natural product coumarins that inhibit human carbonic anhydrases. Bioorg Med Chem. 2013 Mar 15; 21(6):1539-43.

Dimethylfraxetin

Density: 1.2 ± 0.1 g / cm3
Boiling Point: 408.0 ± 45.0 ° C at 760 mmHg
Melting Point: 104-105 º C
Molecular Formula: c12h12o5
Molecular Weight: 236.221
Flash Point: 184.3 ± 28.8 ° C
Accurate Mass: 236.068466
PSA：57.90000
LogP：1.75
Steam Pressure: 0.0 ± 1.0 mmHg at 25 ° C
Refractive index: 1.545

Dimethylfraxetin Safety Information

Risk statement (Europe): 22
Safety statement (Europe): 22-45
Customs Code: 293220990

Dimethylfraxetin Upstream And Downstream Products

DDimethylfraxetin Upstream Products

CAS 186581-53-3 Diazomethane
CAS No. 486-21-5 Isozinpidine
CAS 107078-01-3 6-hydroxy-7,8-d…
CAS No. 77-78-1 Dimethyl sulfate
DDimethylfraxetin Downstream Products
CAS No.72023-44-0 2,3,4,5-tetrame…

Dimethylfraxetin Customs

Customs Code: 293220990
Chinese overview: 293220990 Other lactones VAT rate: 17.0% Tax rebate rate: 13.0% Regulatory conditions: none MFN tariff: 6.5% General tariff: 20.0%
Declaration elements: product name, composition, content and purpose
Summary：2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

English Alias Of Dimethylfraxetin

6,7,8-trimethoxychromen-2-one
6,7,8-Trimethoxy-2H-chromen-2-one
2H-1-Benzopyran-2-one, 6,7,8-trimethoxy-

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Chinese wholesale Alashinol G，(-)-carinol - Dimethylfraxetin ;6,7,8-Trimethoxycoumarin – Yongjian detail pictures

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Our well-equipped facilities and superb good quality control throughout all stages of manufacturing enables us to guarantee total buyer gratification for Chinese wholesale Alashinol G，(-)-carinol - Dimethylfraxetin ;6,7,8-Trimethoxycoumarin – Yongjian , The product will supply to all over the world, such as: Malawi, Slovakia, Egypt, Our company's main products are widely used all over the world; 80% of our products exported to the United States, Japan, Europe and other markets. All stuff sincerely welcome guests come to visit our factory.
    • The factory has advanced equipment, experienced staffs and good management level, so product quality had assurance, this cooperation is very relaxed and happy!
    5 Stars By Mag from Amsterdam - 2017.07.07 13:00
    The sales person is professional and responsible, warm and polite, we had a pleasant conversation and no language barriers on communication.
    5 Stars By Marjorie from Mongolia - 2018.12.14 15:26
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