Chrysoobtusin Cas No. 70588-06-6
Bioactivity of Chrysoobtusin
Description: chrysoobtusin is an anthraquinone derivative isolated from cassia seed. Women Cassiae has long been used to protect the liver, brighten the eyes and defecate.
Reference: [1]. Zhang WD, et al. Simultaneous determination of aurantio-obtusin, chrysoobtusin, obtusin and 1-desmethylobtusin in rat plasma by UHPLC-MS/MS. Biomed Chromatogr. 2014;28(3):369-374.
[2]. Yang B, et al. Nine components pharmacokinetic study of rat plasma after oral administration raw and prepared Semen Cassiae in normal and acute liver injury rats. J Sep Sci. 2019;42(14):2341-2350.
Physicochemical Properties Of Chrysoobtusin
It is hygroscopic amorphous Tan powder (90% is off white powder)[ α] 16D-12.8。 (C = 4.6, methanol), tetraacetate is colorless acicular crystal, melting point: 196 ℃. Paeoniflorin is stable in acidic environment (pH 2 ~ 6) and unstable in alkaline environment.
Content Determination
Density: 1.3 ± 0.1 g / cm3
Boiling point: 586.2 ± 50.0 ° C at 760 mmHg
Melting point: 215-216 º C
Molecular formula: c19h18o7
Molecular weight: 358.342
Flash point: 212.4 ± 23.6 ° C
Accurate mass: 358.105255
PSA: 91.29000
LogP: 91.29000
Steam pressure: 0.0 ± 1.7 mmHg at 25 ° C
Customs Data On Chrysoobtusin
Customs Code: 2914690090
Chinese Overview: 2914690090 others VAT rate: 17.0%, tax rebate rate: 9.0%, regulatory conditions: no MFN tariff: 5.5%, ordinary tariff: 30.0%
