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Essential Information

Extraction source: Platycodon grandiflorum (Jacq.) A.DC. Dry roots.

Detection mode: HPLC ≥ 98%.

Specifications: 20mg, 50mg, 100mg, 500mg, 1g (can be packaged according to customer requirements).

Character: It is white crystalline powder.

Purpose: Used for content determination.

Loss on drying: ≤ 2%

Purity: 95%, 98%, 99%

Analytical Method: HPLC-DAD ＾ or / and ＾ HPLC-ELSD

Identification methods: mass spectrometry (mass), nuclear magnetic resonance (NMR)

Storage: sealed and protected from light, – 20 ℃.

Precautions: This product should be stored at low temperature and dry. Special products should be stored under nitrogen. If it is not stored for a long time, the content will be reduced.

Validity: 2 years

It can meet a large number of demands above gram level. Please consult for details.

Bioactivity Of Platycodin D

Description: platycodin D is a saponin compound isolated from orange stalk, which is AMPK α It has anti obesity activity.

 Related Categories: signaling pathway > > epigenetics > > AMPK

Signal pathway > > PI3K / Akt / mTOR signal pathway > > AMPK

Research field > > metabolic diseases

Target: AMPK α [1]

References: [1]  Kim HL, et al. Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis. Phytomedicine. 2019 Jan; 52:254-263.

Physicochemical Properties of Platycodin D

Density: 1.6 ± 0.1 g / cm3

Molecular formula: c57h92o28

Molecular weight: 1225.324

Exact mass: 1224.577515

PSA: 453.28000

LogP: -0.69

Refractive index: 1.659