Factory directly Rehmannioside D - Ophiopogonin D Cas No.945619-74-9 – Yongjian
Factory directly Rehmannioside D - Ophiopogonin D Cas No.945619-74-9 – Yongjian Detail:
Ophiopogon Saponin D Name
English Name: (1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-6-deoxy-β-D-galactopyranoside
Bioactivity of Ophiopogon Japonicus Saponin D
Description: Ophiopogon D is a rare natural C29 steroidal glycoside isolated from the tuber of Ophiopogon japonicus. Ophiopogonin D is a CYP2J3 inducer that increases CYP2J2 / eets and PPAR in human umbilical vein endothelial cells (HUVECs) α The expression of Ang II significantly inhibited Ang II induced NF- κ B nuclear translocation, I κ B α Down regulation, intracellular Ca2 + overload and activation of proinflammatory cytokines. Ophiopogonin D has been used to treat inflammation and cardiovascular diseases for thousands of years.
Relevant Categories
Signaling pathway > > transmembrane transport > > calcium channel
Research field > > cardiovascular disease
Signaling pathway > > cell cycle / DNA damage > > PPAR
Research field > > inflammation / immunity
Target
PPARα
NF-κB
Ca2+
Reference Documents: [1]. Wang L , et al. Homo-aro-cholestane, furostane and spirostane saponins from the tubers of Ophiopogonjaponicus. Phytochemistry. 2017 Apr;136:125-132.
[2]. Huang X, et al. Ophiopogonin D and EETs ameliorate Ang II-induced inflammatory responses via activating PPARα in HUVECs. Biochem Biophys Res Commun. 2017 Aug 19;490(2):123-133.
English Alias of Ophiopogon saponin D
(1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-6-deoxy-β-D-galactopyranoside β-D-Galactopyranoside, (1β,3β,25R)-3-hydroxyspirost-5-en-1-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-xylopyranosyl-(1->3)]-6-deoxy-
(2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-5-hydroxy-2-(((4R,5′R,6R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-4-hydroxy-5′,6a,8a,9-tetramethyl-1,3,3′,4,4′,5,5′,6,6a,6b,6′,7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2′-pyran]-6-yl)oxy)-6-methyl-4-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol
Ophiopogonin D
Deacetylophiopogonin C
Product detail pictures:
Related Product Guide:
"Sincerity, Innovation, Rigorousness, and Efficiency" could be the persistent conception of our organization for your long-term to establish alongside one another with shoppers for mutual reciprocity and mutual benefit for Factory directly Rehmannioside D - Ophiopogonin D Cas No.945619-74-9 – Yongjian , The product will supply to all over the world, such as: Kyrgyzstan, Florida, Frankfurt, We will do our utmost to cooperate & satisfied with you relying on top-grade quality and competitive price and best after service ,sincerely look forward to cooperating with you and make achievements in the future!
By Agatha from Nepal - 2017.10.13 10:47
The company can keep up with the changes in this industry market, product updates fast and the price is cheap, this is our second cooperation, it's good.
By Steven from Mexico - 2017.04.08 14:55