page_head_bg

Products

Factory making Tubuloside A - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

We are going to make every single effort for being excellent and excellent, and accelerate our ways for standing while in the rank of international top-grade and high-tech enterprises for Cas No.46992-81-8 peucedanol , Cas No.16290-07-6 Kaempferol-7-glucopyranoside , Arnicolide C , Your support is our eternal power! Warmly welcome customers at home and abroad to visit our company.
Factory making Tubuloside A - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian Detail:

Essential Information

CAS No.: 524-30-1 [1]

EINECS No.: 208-355-5

Molecular Formula: c16h18o10

Molecular Weight: 370.3081

Molecular Structure: (Figure 1)

Properties: Light yellow acicular crystal or flake crystal.

Density: 1.634g/cm3

Boiling Point: 722.2 ° C at 760 mmHg

Flash Point: 267 ° C

Steam Pressure: 6.87e-22mmhg at 25 ° C

Bioactivity of Fraxin

Description: Fraxin can be isolated from Acer tegmentosum, F. ornus and a. hippocastanum. It is a glycoside of fraxine [1] and has antioxidant, anti-inflammatory and anti metastasis activities. Fraxin exhibits antioxidant activity by inhibiting cyclic adenylate phosphodiesterase [2].

Target: cyclo AMP phosphodiesterase enzyme [2]

In Vitro Study: Fraxin (100 μ M) It has no cytotoxicity to Hep G2 cells. Fraxin at non cytotoxic concentrations significantly reduced t-BHP induced ROS production in a dose-dependent manner [1]. Fraxin (0.5 mm) can scavenge free radicals at high concentration and has cytoprotective effect on H2O2 mediated oxidative stress [2].

In vivo study: Fraxin (50 mg / kg, PO) significantly blocked CCl4 induced elevation of ALT and AST. Fraxin (10 and 50 mg / kg, PO) significantly reduced GSSG levels (1.7 ± 0.3 and 1.5 ± 0.2 nm / g liver, respectively) compared with GSSG levels in the CCl4 treated group

Reference:. Fraxin (50 mg/kg, p.o.) significantly blocks the CCl4-induced elevation of ALT and AST. Fraxin (10 and 50 mg/kg, p.o.) significantly reduces the GSSG levels (1.7±0.3 and 1.5±0.2 nM/g liver, respectively) compared with the GSSG levels of the CCl4-treated group[1].

[2]. Whang WK, et al. Natural compounds,fraxin and chemicals structurally related to fraxin protect cells from oxidative stress. Exp Mol Med. 2005 Oct 31;37(5):436-46.


Product detail pictures:

Factory making Tubuloside A - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1  –  Yongjian detail pictures

Factory making Tubuloside A - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1  –  Yongjian detail pictures


Related Product Guide:

Our commission is always to provide our customers and clientele with best quality and aggressive portable digital products for Factory making Tubuloside A - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian , The product will supply to all over the world, such as: Detroit, Honduras, Berlin, We've a good reputation for stable quality solutions, well received by customers at home and abroad. Our company would be guided by the idea of "Standing in Domestic Markets, Walking into International Markets". We sincerely hope that we could do business with customers both at home and abroad. We expect sincere cooperation and common development!
  • Production management mechanism is completed, quality is guaranteed, high credibility and service let the cooperation is easy, perfect!
    5 Stars By Griselda from Mecca - 2018.06.12 16:22
    This company has a lot of ready-made options to choose and also could custom new program according to our demand, which is very nice to meet our needs.
    5 Stars By Brook from Bulgaria - 2017.11.11 11:41
    Write your message here and send it to us