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Bioactivity of Chrysoobtusin

Description: chrysoobtusin is an anthraquinone derivative isolated from cassia seed. Women Cassiae has long been used to protect the liver, brighten the eyes and defecate.

Reference: [1]. Zhang WD, et al. Simultaneous determination of aurantio-obtusin, chrysoobtusin, obtusin and 1-desmethylobtusin in rat plasma by UHPLC-MS/MS. Biomed Chromatogr. 2014;28(3):369-374.
[2]. Yang B, et al. Nine components pharmacokinetic study of rat plasma after oral administration raw and prepared Semen Cassiae in normal and acute liver injury rats. J Sep Sci. 2019;42(14):2341-2350.

Physicochemical Properties Of Chrysoobtusin

It is hygroscopic amorphous Tan powder (90% is off white powder)[ α] 16D-12.8。 (C = 4.6, methanol), tetraacetate is colorless acicular crystal, melting point: 196 ℃. Paeoniflorin is stable in acidic environment (pH 2 ~ 6) and unstable in alkaline environment.

Content Determination

Density: 1.3 ± 0.1 g / cm3

Boiling point: 586.2 ± 50.0 ° C at 760 mmHg

Melting point: 215-216 º C

Molecular formula: c19h18o7

Molecular weight: 358.342

Flash point: 212.4 ± 23.6 ° C

Accurate mass: 358.105255

PSA: 91.29000

LogP: 91.29000

Steam pressure: 0.0 ± 1.7 mmHg at 25 ° C

Customs Data On Chrysoobtusin

Customs Code: 2914690090

Chinese Overview: 2914690090 others VAT rate: 17.0%, tax rebate rate: 9.0%, regulatory conditions: no MFN tariff: 5.5%, ordinary tariff: 30.0%