Factory source Prim-O-glucosylcimifugin - Narirutin – Yongjian
Factory source Prim-O-glucosylcimifugin - Narirutin – Yongjian Detail:
Application Of Narirutin
Narirutin is one of the active components isolated from citrus unshiu, which has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti tuberculosis effect.
Name Of Narirutin
English Name: narirutin
Chinese Alias: naringin-7-o-rutoside | naringin
Bioactivity Of Narirutin
Description: narirutin is one of the active ingredients isolated from citrus unshiu. It has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti tuberculosis effect.
Related Categories: signal path > > other > > other
Research Field > > inflammation / immunity
References: [1] Sahu PK, et al. Structure-based Discovery of Narirutin as a Shikimate Kinase Inhibitor with Anti-tubercular Potency. Curr Comput Aided Drug Des. 2019 Oct 25.
[2]. Funaguchi N, et al. Narirutin inhibits airway inflammation in an allergic mouse model. Clin Exp Pharmacol Physiol. 2007 Aug; 34(8):766-70.
Physicochemical Properties Of Narirutin
Density: 1.7 ± 0.1 g / cm3
Boiling Point: 924.3 ± 65.0 ° C at 760 mmHg
Melting Point: 152-190 º C
Molecular Formula: C27H32O14
Molecular Weight: 580.535
Flash Point: 307.3 ± 27.8 ° C
Accurate Mass: 580.179199
PSA:225.06000
LogP:2.07
Appearance: off white powder
Steam Pressure: 0.0 ± 0.3 mmHg at 25 ° C
Refractive Index: 1.708
Safety Information Of Narirutin
Safety Statement (Europe): 22-24 / 25
Transport Code Of dangerous Goods: nonh for all modes of transport
Customs Code: 29389090
Narirutin Literature
Berry and Citrus Phenolic Compounds Inhibit Dipeptidyl Peptidase IV: Implications in Diabetes Management.
Evid. Based. Complement. Alternat. Med. 2013 , 479505, (2013)
Beneficial health effects of fruits and vegetables in the diet have been attributed to their high flavonoid content. Dipeptid
Huanglongbing modifies quality components and flavonoid content of ‘Valencia’ oranges.
J. Sci. Food Agric. 96 , 73-8, (2016)
In order to evaluate the effect of citrus greening disease, or Huanglongbing (HLB), on quality components and flavonoid contents of ‘Valencia’ oranges, fruit from non-infected trees (control), from in…
English Alias Of Narirutin
(2S)-5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl-6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
(2S)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranoside
ISONARINGIN
Isonaringenin
Naringenin 7-O-rutinoside
4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2S)-
Naringenin-7-rutinoside
(2S)-5-Hydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromen-4-one
Narirutin
(2S)-5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
(2S)-5-Hydroxy-2-(4-hydroxyphényl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}méthyl)tétrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromén-4-one
Naringenin 7-rutinoside
(S)-7-((6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
naringenin-7-O-rutinoside
Apigenin-7-rutinosid
(2S)-5-Hydroxy-2-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromen-4-on
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