Formononetin;7-Hydroxy-4’-Methoxyisoflavone
Application Of Formononetin
Formononetin (formononetil; flavoril), extracted from red clover, can inhibit the proliferation of DU-145 / PC-3 cells in a dose-dependent manner.
Name Of Formononetin
Chinese Name:formononetin
Chinese Name: 7-hydroxy-3 - (4-methoxyphenyl) chromone | shengyuanchanning B | anthocyanin | anthocyanin | anthocyanin | 7-hydroxy-4-methoxyisobenzone | 7-hydroxy-4 '- methoxyisoflavone | 7-hydroxy-4' - methoxyisoflavone
Bioactivity of Formononetin
Description: formononetin (formononetil; flavor) is extracted from red clover and can inhibit the proliferation of DU-145 / PC-3 cells in a dose-dependent manner.
Related Categories: Natural Products > > flavonoids
Research field > > cancer
Reference: [1]. Liu XJ, et al. Up-regulating of RASD1 and apoptosis of DU-145 human prostate cancer cells induced by formononetin in vitro. Asian Pac J Cancer Prev. 2014;15(6):2835-9.
[2]. Zhang X, et al. Formononetin induces apoptosis in PC-3 prostate cancer cells through enhancing the Bax/Bcl-2 ratios and regulating the p38/Akt pathway. Nutr Cancer. 2014;66(4):656-61.
[3]. Chen J, et al. Formononetin induces cell cycle arrest of human breast cancer cells via IGF1/PI3K/Akt pathways in vitro and in vivo. Horm Metab Res. 2011 Sep;43(10):681-6.
Physicochemical Properties of Formononetin
Density: 1.3 ± 0.1 g / cm3
Boiling Point: 479.4 ± 45.0 ° C at 760 mmHg
Melting Point: 256-260 ° C
Molecular Formula: C16H12O4
Molecular Weight: 268.264
Flash Point: 183.4 ± 22.2 ° C
Exact Mass: 268.073547
PSA:59.67000
Appearance: off white powder
Steam Pressure: 0.0 ± 1.2 mmHg at 25 ° C
Refractive Index: 1.641
Storage Conditions: sealed and stored in a ventilated and dry place to avoid contact with other oxides.
Stability: use and store according to the specifications without decomposition and avoid contact with oxides
Toxicity And Ecology Of Formononetin
Ecological data of Formononetin
This substance may be harmful to the environment, so special attention should be paid to the water body.
Formononetin safety information
Symbol: 
Signal Word: warning
Hazard Statement: h315-h319-h335
Warning Statement: p280-p305 + P351 + p338-p337 + P313
Personal Protective equipment: dust mask type N95 (US); Eyeshields; Gloves
Hazard Code (Europe): Xi: iritant
Risk Statement (Europe): R36 / 37 / 38
Safety Statement (Europe): S37 / 39-s26-s36
Transport Code of dangerous goods: nonh for all modes of transport
Customs Code: 2932990099
Formononetin Customs
Customs Code: 2932990099
Chinese overview: 2932990099 Other heterocyclic compounds containing only oxygen heteroatoms VAT rate: 17.0% Tax rebate rate: 13.0% Regulatory conditions: none MFN tariff: 6.5% General tariff: 20.0%
Declaration elements: 2932990099 Other heterocyclic compounds containing only oxygen heteroatoms VAT rate: 17.0% Tax rebate rate: 13.0% Regulatory conditions: none MFN tariff: 6.5% General tariff: 20.0%
Summary:2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Formononetin Literature
Flavonoids as a scaffold for development of novel anti-angiogenic agents: An experimental and computational enquiry.
Arch. Biochem. Biophys. 577-578 , 35-48, (2015)
Relationship between structural diversity and biological activities of flavonoids has remained an important discourse in the mainstream of flavonoid research. In the current study anti-angiogenic, cyt...
Preparation and evaluation of surface-bonded tricationic ionic liquid silica as stationary phases for high-performance liquid chromatography.
J. Chromatogr. A. 1396 , 62-71, (2015)
Two tricationic ionic liquids were prepared and then bonded onto the surface of supporting silica materials through "thiol-ene" click chemistry as new stationary phases for high-performance liquid chr...
Sodium Hydroxide Enhances Extractability and Analysis of Proanthocyanidins in Ensiled Sainfoin (Onobrychis viciifolia).
J. Agric. Food Chem. 63 , 9471-9, (2015)
Little information exists on the effects of ensiling on condensed tannins or proanthocyanidins. The acetone-butanol-HCl assay is suitable for measuring proanthocyanidin contents in a wide range of sam...
English Alias Of Formononetin
4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-methoxyphenyl)-
7-hydroxy-4'-methoxy-Isoflavone (8CI)
8-Hydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one
Formononetol
4'-O-methyl-daidzein
4H-1-Benzopyran-4-one, 7-hydroxy-3- (4-methoxyphenyl)-
BIOCHANIN B
ForMonentin
BIOCHANIN A
Flavosil
7-Hydroxy-4'-methoxyisoflavone
Neochanin
Myconate
MFCD00016948
BiocaninB
FORMONETIN
8-Hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one
EINECS 207-623-9
Formononetin
7-Hydroxy-3-(4-methoxyphenyl)chromone
forMonoetin
