Ophiopogonin D Cas No.945619-74-9
Ophiopogon Saponin D Name
Sunan Ingilishi:(1β,3β,25R) -3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)] -6-deoxy-β-D-galactpyranoside
Bioactivity na Ophiopogon Japonicus Saponin D
Bayani:Ophiopogon D wani nau'in halitta ne na C29 steroidal glycoside wanda ba kasafai ba keɓe daga tuber na Ophiopogon japonicus.Ophiopogonin D shine mai haifar da CYP2J3 wanda ke haɓaka CYP2J2 / eets da PPAR a cikin ƙwayoyin jijiyoyi na endothelial na jikin mutum (HUVECs) α Maganar Ang II ta hana Ang II haifar da NF-κ B fassarar nukiliya, I κ B α Down ka'idojin 2 + intracellular overload da kunna proinflammatory cytokines.An yi amfani da Ophiopogonin D don magance kumburi da cututtukan zuciya na dubban shekaru.
Abubuwan da suka dace
Hanyar sigina > > jigilar jigilar kaya > > tashar calcium
Filin bincike > > cututtukan zuciya
Hanyar sigina > > sake zagayowar salula / lalata DNA > > PPAR
Filin bincike > > kumburi / rigakafi
manufa
PPARA
NF-κB
Ca2+
Takardun Magana:[1].Wang L, et al.Homo-aro-cholestane, furostane da spirostane saponins daga tubers na Ophiopogonjaponicus.Ilimin kimiyya.2017 Afrilu; 136: 125-132.
[2].Huang X, et al.Ophiopogonin D da EETs suna haɓaka martanin kumburin Ang II ta hanyar kunna PPARA a cikin HUVECs.Biochem Biophys Res Commun.2017 Agusta 19; 490 (2): 123-133.
Harshen Turanci na Ophiopogon saponin D
(1β,3β,25R) -3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)] -6-deoxy-β-D-galactopyranoside β-D-Galactopyranoside, (1β,3β,25R) -3-hydroxyspirost-5-en-1-yl O-6-deoxy-α-L-mannopyranosyl-(1- >2)-O-[β-D-xylopyranosyl-(1->3)]-6-deoxy-
(2S,3R,4R,5R,6S)-2-((2R,3R,4S,5S,6R)-5-hydroxy-2-(((4R,5'R,6R,6aR,6bS,8aS ,8bR,9S,10R,11aS,12aS,12bS)-4-hydroxy-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a, 6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2 '-pyran] -6-yl) oxy) -6-methyl-4-((2S,3R,4S,5R) -3,4,5-trihydroxytetrahydro-2H-pyran-2-yl) oxy) tetrahydro- 2H-pyran-3-yl) oxy) -6-methyltetrahydro-2H-pyran-3,4,5-triol
Ophiopogonin D
Deacetylophiopogonin C
