Chlorogenic Acid CAS No.327-97-9
ʻIke Pono
Loaʻa i ka chlorogenic acid ka nui o nā hopena antibacterial, akā hiki ke hoʻopau ʻia e nā protein in vivo.E like me ka caffeic acid, waha a i ʻole intraperitoneal injection hiki ke hoʻomaikaʻi i ka excitability waena o nā ʻiole.Hiki iā ia ke hoʻonui i ka peristalsis o ka ʻōpū o nā ʻiole a me nā ʻiole a me ka ʻeha o ka ʻōpū o ka ʻiole.Loaʻa iā ia ka hopena cholagogic a hiki ke hoʻonui i ka huna bile i nā ʻiole.Loaʻa ka hopena sensitization i nā kānaka.Hiki ke loaʻa ka hānō a me ka dermatitis ma hope o ka hanu ʻana i ka lepo mea kanu i loko o kēia huahana.
Inoa Pākē: Chlorogenic acid
Inoa haole: Chlorogenic acid
Ke Kinohi Kinohi: C16H18O9
Kaumaha Molekala: 354.31
CAS No.:327-97-9
Ka helu hehee: 208 ℃;
Puni paila: 665 ℃;
Māmā: 1.65 g / cm ³
Kaila uila: 245.5 ℃
Hōʻike Hōʻikeʻike: - 37 °
ʻIkepili Toxicology
ʻAiʻawaʻawaʻawaʻawa: liʻiliʻi make make (iole, ʻōpū ʻōpū) 4000mg / kg
ʻIkepili Kaiaola
Nā hopena pōʻino ʻē aʻe: hiki ke hoʻopōʻino ka waiwai i ke kaiapuni, a pono e nānā pono i ke kino wai.
Puna
Eucommia ulmoides Oliv Lonicera dasytyla Rehd ʻO nā ʻōpuʻu pua maloʻo a i ʻole me nā pua mohala, ka hua o British Hawthorn ma Rosaceae, cauliflower i dioscoreaceae, Salix mandshurica ma Apocynaceae, Polypodiaceae mea kanu Eurasian wai keel rhizome, Verbenaceae mea kanu pseudopaciferous leaf kumulāʻau. , Polygonaceae kanu palahalaha waiho mau mauu, Rubiaceae kanu tarpaulin mauu holookoa, honeysuckle kanu capsule Zhai mauu holookoa.ʻO nā lau ʻuala i ka ʻohana Convolvulaceae.ʻO nā ʻanoʻano o ke kofe hua liʻiliʻi, kofe hua waena a me ka kofe hua nui.Nā lau a me nā aʻa o Arctium lappa
Ka hoʻohana ʻana o Chlorogenic Acid
Loaʻa i ka waika Chlorogenic kahi ʻano hana olaola.ʻO ka noiʻi e pili ana i nā hana olaola o ka chlorogenic acid i ka ʻepekema hou ua hele hohonu i nā ʻano he nui, e like me ka meaʻai, mālama ola kino, lāʻau lapaʻau, ʻoihana kemika i kēlā me kēia lā a pēlā aku.ʻO ka waika Chlorogenic kahi waiwai bioactive koʻikoʻi, nona nā hana o ka antibacterial, antiviral, hoʻonui i ka leukocyte, pale i ka ate a me ka gallbladder, anti-tumor, hoʻohaʻahaʻa i ke koko, hoʻohaʻahaʻa i ke koko lipid, scavenging free radical a me ka hoihoi i ka ʻōnaehana nerve waena.
Antibacterial a me antiviral
ʻO ka Eucommia ulmoides chlorogenic acid ka ikaika antibacterial a me nā hopena anti-inflammatory, aucubin a me kāna mau polymers i nā hopena antibacterial maopopo, a he hopena hoʻoneʻe ko aucubin i ka Gram-negative a me ka maikaʻi bacteria.Loaʻa i ka Aucubin nā hopena bacteriostatic a me diuretic, a hiki ke hoʻoikaika i ka ho'ōla ʻeha;Hiki i ka Aucubin a me ka glucoside ke hana i ka hopena antiviral ma hope o ka moʻomeheu mua, akā ʻaʻohe ona hana antiviral.Ua hōʻoia ka Institute of aging Medical Sciences, Aichi Medical University, i ka waiwai alkaline i lawe ʻia mai Eucommia ulmoides Oliv.Loaʻa iā ia ka hiki ke hoʻopau i ka maʻi ʻōnaehana pale kanaka.Hiki ke hoʻohana ʻia kēia mea e pale a mālama i ka AIDS.
Antioxidation
ʻO ka waika Chlorogenic kahi antioxidant phenolic maikaʻi.ʻOi aku ka ikaika o kona mana antioxidant ma mua o ka waika caffeic, p-hydroxybenzoic acid, ferulic acid, syringic acid, butyl hydroxyanisole (BHA) a me tocopherol.He hopena antioxidant ka waika chlorogenic no ka mea aia kekahi nui o R-OH radical, hiki ke hana i ka radical hydrogen me ka hopena antioxidant, i mea e hoʻopau ai i ka hana o ka hydroxyl radical, superoxide anion a me nā radical manuahi ʻē aʻe, i mea e pale ai i nā ʻiʻo mai ka oxidative. poino.
ʻO ka hoʻomaʻemaʻe radical manuahi, anti-aging, anti musculoskeletal aging
ʻOi aku ka ikaika o ka waikawa chlorogenic a me kāna mau derivatives ma mua o ka ascorbic acid, caffeic acid a me ka tocopherol (vitamin E), hiki ke hoʻopau maikaʻi i ka DPPH free radical, hydroxyl free radical a me superoxide anion free radical, a hiki nō hoʻi ke kāohi i ka oxidation o ka haʻahaʻa haʻahaʻa. lipoprotein.He kuleana koʻikoʻi ka chlorogenic acid i ka hoʻomaʻamaʻa maikaʻi ʻana i nā radical manuahi, mālama i ke ʻano maʻamau a me ka hana o nā ʻāpana kino, pale a hoʻopaneʻe i ka hiki ʻana mai o ka mutation tumor a me ka ʻelemakule.Loaʻa i ka Eucommia chlorogenic acid kahi mea kūikawā e hiki ke hāpai i ka synthesis a me ka decomposition o collagen i loko o ka ʻili kanaka, iwi a me ka ʻiʻo.Loaʻa iā ia ka hana e hoʻoikaika i ka metabolism a pale i ka emi ʻana.Hiki ke hoʻohana ʻia e pale i ka emi ʻana o ka iwi a me ka ʻiʻo ma muli o ke kaumaha ʻole o ka lewa.I ka manawa like, ʻike ʻia ʻo Eucommia chlorogenic acid he hopena anti-free radical i loko o vivo a me in vitro.
Ka pale ʻana i ka mutation a me ka antitumor
Ua hōʻike ʻia nā hoʻokolohua lāʻau lapaʻau o kēia wā e loaʻa i ka Eucommia ulmoides chlorogenic acid nā hopena anti-cancer a me anti-cancer.Ua aʻo ka poʻe loea Iapana i ka antimutagenicity o ka Eucommia ulmoides chlorogenic acid a ua ʻike ua pili kēia hopena i nā ʻāpana anti mutagenic e like me ka chlorogenic acid, e hōʻike ana i ke koʻikoʻi nui o ka chlorogenic acid i ka pale ʻana i ka maʻi tumora.
Hiki i nā polyphenols i loko o nā mea kanu a me nā huaʻai, e like me ka waikawa chlorogenic a me ka waikawa caffeic, hiki ke kāohi i ka mutagenicity o nā carcinogens aflatoxin B1 a me benzo [a] - pyrene ma ke kāohi ʻana i nā enzyme i hoʻāla ʻia;Hiki i ka chlorogenic acid ke hoʻokō i nā hopena anti-cancer a me nā anti-cancer ma o ka hoʻemi ʻana i ka hoʻohana ʻana i nā carcinogens a me kā lākou lawe ʻana i loko o ke ake.Loaʻa i ka waika Chlorogenic nā hopena pale nui i ka maʻi maʻi colorectal, ka maʻi ʻaʻai a me ka maʻi maʻi laryngeal.Manaʻo ʻia ʻo ia he lāʻau pale kemika maikaʻi i ka maʻi kanesa.
Ka hopena pale ma ka ʻōnaehana cardiovascular
Ma ke ʻano he scavenger radical manuahi a me ka antioxidant, ua hōʻoia ʻia ka waikawa chlorogenic e ka nui o nā hoʻokolohua.Hiki i kēia hana olaola o ka chlorogenic acid ke pale i ka ʻōnaehana cardiovascular.He hopena koʻikoʻi ka Isochlorogenic acid B i ka hoʻolaha ʻana o ka prostacyclin (PGI2) a me ka anti platelet aggregation i nā ʻiole;ʻO ka nui o ka hoʻokuʻu ʻana o SRS-A i hoʻoiho ʻia e ka antibody i nā ʻōpala puaʻa guinea he 62.3%.Ua hoʻolaha pū ʻo Isochlorogenic acid C i ka hoʻokuʻu ʻana o PGI2.Eia kekahi, ʻo ka isochlorogenic acid B he hopena pale ikaika i ka platelet thromboxane biosynthesis a me ka hōʻeha endothelin i hoʻokomo ʻia e ka hydrogen peroxide.
Ka hopena hypotensive
Ua hōʻoia ʻia e nā makahiki he nui o nā hoʻokolohua lapaʻau ʻo Eucommia chlorogenic acid he hopena antihypertensive, hopena curative paʻa, ʻaʻohe mea ʻawaʻawa a ʻaʻohe hopena ʻaoʻao.Ua ʻike ke Kulanui o Wisconsin i nā ʻāpana kūpono o Eucommia ulmoides green e hoʻemi i ke kahe koko he terpineol diglucoside, aucubin, chlorogenic acid, a me Eucommia ulmoides chlorogenic acid polysaccharides.[5]
Nā hana olaola ʻē aʻe
No ka mea, he hopena koʻikoʻi ko ka chlorogenic acid i ka hyaluronic acid (HAase) a me ka glucose-6-phosphatase (gl-6-pase), he hopena ko ka chlorogenic acid i ka ho'ōla ʻana i ka ʻeha, ke olakino ʻili a me ka pulu, ka lubricating ami, ka pale ʻana i ka mumū a me ka ka hoʻoponopono kaulike o ka glucose koko i loko o ke kino.Loaʻa ka chlorogenic acid i nā hopena paʻa a pepehi i nā maʻi like ʻole a me nā maʻi.Loaʻa ka chlorogenic acid i nā hopena pharmacological o ka hoʻohaʻahaʻa ʻana i ke koko, antibacterial, antiviral, anti-inflammatory, hoʻonui i nā keʻokeʻo keʻokeʻo, pale i ka maʻi diabetes, hoʻonui i ka motility gastrointestinal a me ka hoʻolaha ʻana i ka huna huna.Ua hōʻike nā haʻawina e hiki ke hoʻoulu nui i ka waika chlorogenic waha i ka huna ʻana o ka bile a loaʻa ka hopena o ka pōmaikaʻi o ka gallbladder a me ka pale ʻana i ke ake;Hiki iā ia ke pale pono i ka hemolysis o nā erythrocytes ʻiole i hana ʻia e H2O2.