Naringenin-7-O-neohesperidoside;Naringin;Isonaringenin CAS No. 10236-47-2
Hoʻolauna pōkole
inoa Pelekane:naringin
Hoʻohana:hiki ke hoʻohana ʻia e like me ka meaʻai hoʻohui, ka mea nui no ke kōpaʻa koʻikoʻi, nā mea inu ʻoluʻolu, etc.
Nā waiwai physicochemical:ʻO ka naringin kahi paʻakikī o ka glucose, rhamnose a me ka naringin.He keʻokeʻo a ʻulaʻula melemele crystalline pauda.ʻO ka maʻamau, loaʻa iā 6 ~ 8 ka wai aniani me kahi helu hoʻoheheʻe o 83 ℃.Hoʻomaloʻo i ke kaumaha mau ma 110 ℃ no ka loaʻa ʻana o nā kristal me 2 wai aniani, me kahi helu heheʻe o 171 ℃.He ʻona ʻawaʻawa loa ʻo Naringin, a ʻo ka wai wai me ka ʻona o 20mg / kg he ʻono ʻawaʻawa.Hiki ke hoʻoheheʻe ʻia i loko o ka wai, hiki ke hoʻoheheʻe ʻia i ka wai wela, ethanol, acetone a me ka ʻakika acetic glacial mahana.Aia nā pūʻulu phenolic hydroxyl i loko o ka hoʻolālā, a ʻo kona ʻano wai he waika palupalu.ʻO ka huahana "citrus glucoside dihydrochalcone" ma hope o ka hydrolysis a me ka hydrogenation he mea ʻono, a ʻoi aku ka ʻono ma mua o 150 mau manawa o ka sucrose.
Pūnaehana helu
Ka helu CAS: 10236-47-2
Helu MDL: mfcd00149445
EINECS No.: 233-566-4
RTECS Helu: qn6340000
Helu BRN: 102012
ʻIkepili Waiwai Kino
1. Nā ʻano: naringin kahi paʻakikī o ka glucose, rhamnose a me ka grapefruit gametophyte.He keʻokeʻo a ʻulaʻula melemele crystalline pauda.
2. Puni hehee (º C): 171
3. Helu hoʻopaʻapaʻa: - 84
4. Hoʻololi kikoʻī (º): - 91
5. Solubility: hiki ke hoʻoheheʻe iki ʻia i ka wai, hiki ke hoʻoheheʻe ʻia i ka wai wela, ethanol, acetone a me ka ʻakika acetic glacial mahana.
ʻIkepili Toxicology
1. Keʻano ho'āʻo: ka'ōpū'ōpū
Ka nui o ka lawe ʻana: 2 mg / kg
Mea hoʻāʻo: ʻiole rodent
Ke ʻano o ka ʻawaʻawa: acute
Nā hopena ʻawaʻawa: ʻaʻole i hōʻike ʻia nā hopena ʻona a me nā hopena ʻaoʻao koe wale no nā waiwai make ʻē aʻe
2. Keʻano ho'āʻo: ka'ōpū'ōpū
Ka nui o ka lawe ʻana: 2 mg / kg
ʻO ka mea hoʻāʻo: puaʻa puaʻa rodent
Ke ʻano o ka ʻawaʻawa: acute
Nā hopena ʻawaʻawa: ʻaʻole i hōʻike ʻia nā hopena ʻona a me nā hopena ʻaoʻao koe wale no nā waiwai make ʻē aʻe
ʻIkepili Kaiaola
He mea pōʻino paha kēia mea i ke kaiapuni, no laila pono e nānā pono i ke kino wai.
ʻIkepili Hoʻolālā Molecular
1. Helu kuhikuhipuʻuone molar: 135.63
2. Ka nui molar (cm3 / mol): 347.8
3. Ka nui kiko'ī isotonic (90.2k): 1103.4
4. ʻO ka ʻili o ka ʻili (dyne / cm): 101.2
5. Polarizability (10-24cm3): 53.76 [2]
E helu i ka ʻikepili Kimia
1. Waiwai kuhikuhi no ka helu ʻana i ka hoʻohālikelike hydrophobic (xlogp): - 0.5
2. Ka helu o nā mea hāʻawi paʻa hydrogen: 8
3. Ka helu o nā mea hoʻopaʻa paʻa hydrogen: 14
4. Ka helu o nā mea paʻa kemika hiki ke hoʻololi: 6
5. Topological molecular polar surface area (TPSA): 225
6. Ka helu o nā ʻātoma kaumaha: 41
7. Ka uku o ka ʻili: 0
8. Paʻakikī: 884
9. Ka helu o nā ʻātoma isotopic: 0
10. E hoʻoholo i ka helu o nā stereocenters atomika: 11
11. Ka helu o nā stereocenter atomika maopopo ʻole: 0
12. E hoʻoholo i ka heluna o nā stereocenters paʻa kinikini: 0
13. Ka helu o nā stereocenters paʻa kemika paʻa ʻole: 0
14. Ka helu o nā pūʻulu pili covalent: 1
Nā Waiwai a me ka Paʻa
Inā hoʻohana a mālama ʻia e like me nā kikoʻī, ʻaʻole ia e decompose.
Keʻano mālama
Uhi ʻia ka ʻeke ʻeke meaʻai me ka ʻeke pepa kraft no ka hōʻailona sila.E mālama i kahi maloʻo a maloʻo.
Ke kumu
Loaʻa ka hua ʻala i ka naringin, ma kahi o 1%.Aia ma ka ʻili, ka capsule a me ka hua.ʻO ia ka mea ʻawaʻawa nui i ka hua ʻala.He waiwai waiwai ko Naringin a hiki ke hoʻohana ʻia e hana i nā mea ʻono dihydrochalcone hou, a me nā lāʻau lapaʻau no ka pale ʻana a me ka mālama ʻana i ka maʻi cardiovascular, allergy a me ka mumū.
1. Hiki ke hoʻohana ʻia ma ke ʻano he mea hoʻohui edible, ka mea nui no ke kōpaʻa koʻikoʻi, nā mea inu ʻoluʻolu, etc.
2. Hiki ke hoʻohana 'ia e like me maka mea no ka synthesis o hou sweeteners dihydronaringin chalcone a me neohesperidin dihydrochalcone me kiʻekiʻeʻono, non toxicity a me ka haʻahaʻa ikehu.
ʻO ke ʻano unuhi
Hiki ke hoʻoheheʻe ʻia ʻo Naringin i ka waiʻona a me ka hopena alkali, a hiki ke hoʻoheheʻe ʻia i ka wai wela.E like me kēia ʻano, lawe pinepine ʻia ka naringin e ke ʻano alkali a me ke ʻano wai wela.Penei ke kaʻina hana: ʻO ka Pomelo Peel → ka ʻohi ʻana → ka hoʻolei ʻana me ka wai lime a i ʻole ka wai wela → kānana → ka hoʻoluʻu a me ka ua → ka hoʻokaʻawale ʻana → ka maloʻo a me ka ʻoki ʻana → ka huahana i pau.
Ka Wai wela
ʻO ke kaʻina hana hoʻoheheʻe wai wela penei: ma hope o ka ʻili ʻana o ka pomelo, e hoʻohui i 3 ~ 4 mau manawa o ka wai, wela a hoʻolapalapa no 30min, a kaomi i ka filtrate.Hiki ke hana hou i keia hana 2 ~ 3 manawa.Ma hope o ka hoʻopili ʻana o ka filtrate no 3 ~ 5 mau manawa, ʻo ia nō (0 ~ 3 ℃) e hoʻoheheʻe a crystallize, kānana a hoʻokaʻawale ʻia, a ʻo ka precipitate ka huahana crude.Hiki ke hoʻomaʻemaʻe ʻia me ka waiʻona a i ʻole ka wai wela.He haʻahaʻa ka hoʻihoʻi hou ʻana o kēia ʻano a me ka manawa ua lōʻihi.I kēia mau lā, ua hoʻomaikaʻi ka Citrus Research Institute of Chinese Academy of Agricultural Science i ke ʻano, ʻo ia hoʻi, mālama ʻia ka extract me ka hū a i ʻole pectinase, e hoʻopōkole i ka manawa ua a hoʻomaikaʻi i ka hua a me ka maʻemaʻe ma kahi o 20% ~ 30%.Hiki ke hoʻohana ʻia ke koena o ka peel e unuhi i ka pectin.
Kaʻina Alkali
ʻO ke ʻano alkali ka hoʻoinu ʻana i ke koena ʻili i ka wai lime (pH12) no 6 ~ 8h a kaomi iā ia e loaʻa ai ka kānana.E kau i ka filtrate i loko o ka ipu sanwiti, e hoʻokaʻawale iā ia me ka 1: 1 hydrochloric acid i ka pH 4.1 ~ 4.4, e hoʻomehana iā 60 ~ 70 ℃, a mālama i ka mahana no 40 ~ 50min.A laila e hoʻomaha i ka haʻahaʻa haʻahaʻa e hoʻoheheʻe i ka naringin, e hōʻiliʻili i ka precipitate, e hoʻomaloʻo i ka wai me ka centrifuge, e waiho i loko o ka lumi maloʻo, e hoʻomaloʻo iā ia ma 70 ~ 80 ℃, e ʻoki a wili iā ia i loko o ka pauka maikaʻi, ʻo ia ka huahana crude.E hana hou i ka crystallization me ka waiʻona wela no 2 ~ 3 mau manawa e loaʻa ai ka huahana maʻemaʻe.
Hoʻomaikaʻi ʻia ka hana
Me ke ʻano o luna, ʻo ke kō, ka pectin, ka protein, ka puaʻa a me nā mea ʻē aʻe i loko o ka ʻili pomelo e komo i ka hopena o ka unuhi ʻana i ka manawa like, e hopena i ka maʻemaʻe huahana haʻahaʻa a me ka recrystallization multi-step no ka hoʻomaʻemaʻe.No laila, lōʻihi ka manawa unuhi, paʻakikī ke kaʻina hana, a hoʻonui ʻia ka solvent, ka ikehu a me ke kumukūʻai.I mea e maʻalahi ai ke kaʻina hana, hoʻomaikaʻi i ka maʻemaʻe o nā huahana a hōʻemi i ke kumukūʻai, nui nā noiʻi i hana ʻia ma ke kaʻina hana hoʻihoʻi o naringin.Li Yan et al.(1997) hoʻohana i ka ultrafiltration e hoʻomaʻamaʻa i ka naringin extract.Hiki ke hoʻonui ʻia ka maʻemaʻe o ka huahana i loaʻa i ka crystallization mai 75% o ke ʻano alkali kuʻuna i 95%.ʻO nā kūlana hana o ka ultrafiltration penei: kaomi 0.15 ~ 0.25MPa, kahe kahe 180L / h, pH 9 ~ 10 a me ka mahana ma kahi o 50 ℃.Ua hoʻomaʻemaʻe maikaʻi ʻo Iapana Itoo (1988) i ka naringin me ka macroporous adsorption resin diaion HP-20.Wu houjiu et al.(1997) hōʻike hoʻi i kekahi mau home macroporous adsorption resins maikaʻi adsorption a me analytical waiwai no ka naringin, i hiki ke hoʻohana no ka hookaawale a me ka hoʻomaʻemaʻe o naringin.I ka hōʻuluʻulu manaʻo, hoʻopuka ka mea kākau i ke kaʻina hana i hoʻomaikaʻi ʻia.Penei ke kahe ana o ka pakuhi: Pomelo Peel → kuʻi → hoʻoheheʻe wai wela → kānana → ultrafiltration → ultrafiltration permeate → resin adsorption → analytical solution → hoʻopaʻa haʻahaʻa → hoʻomaloʻo hau → hoʻokaʻawale → kaukani maloʻo → huahana pau.
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