Esculin;Aesculin;Esculoside;Bicolorin;Escosyl
Daim ntawv thov Esculin
Bioflavonoids, antioxidant, txhawb cov ntsiab lus ntawm vitamin C.
Kev ua ntawm Esculin
1. Kev tiv thaiv kab mob thiab tshuaj tua kab mob: nas tau txhaj tshuaj intraperitoneally nrog 10mg / kg.Carrageenan induced, dextrose induced, serotonin induced thiab histamine induced "mob caj dab" muaj inhibitory teebmeem, thiab inhibitory intensities yog 35,28,20,8% raws li nws kuj tau tshaj tawm tias nws muaj inhibitory nyhuv ntawm formaldehyde induced mob caj dab, tab sis cov nyhuv yog tsis muaj zog tshaj li ntawm carrageenan induced mob caj dab;Qhov inhibition ntawm dextran mob caj dab tsis pom tseeb Nws tuaj yeem cuam tshuam qhov tsim ntawm granuloma hauv nas (paj rwb txoj kev), erythema cov tshuaj tiv thaiv los ntawm ultraviolet hluav taws xob nyob rau sab nraum qab ntawm guinea npua, thiab nce capillary permeability tshwm sim los ntawm histamine Nws muaj zog analgesic nyhuv. .
2. Cov nyhuv ntawm cov zis ntim thiab uric acid excretion: ntau txoj kev tswj hwm tuaj yeem txhim kho uric acid excretion hauv nas thiab luav, thiab tsis muaj diuretic nyhuv rau cov nas ib txwm, tab sis muaj cov nyhuv diuretic tseem ceeb rau cov nas.
3.Lwm yam: antibacterial, anticoagulant thiab inhibiting aldose reductase nyob rau hauv nas lo ntsiab muag.
Lub npe Esculin
Lub npe Askiv: esculin
Suav Lub Npe: Heptachlor hemihydrate |heptachlor hemihydrate |6-(β- D-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-ib |aescin |nees chestnut bark glycoside |txiv ntseej bark glycoside Xya nplooj dab Aescin |Qiyeling |txiv ntseej bark glycoside |aescin |6 - (beta-d-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-ib
Bioactivity ntawm Esculin
Nqe lus piav qhia: esculin yog fluorescent coumarin glucoside, uas yog cov khoom siv zoo ntawm cov tawv ntoo grey.Esculin txhim kho kev paub tsis meej hauv kev sim ntshav qab zib nephropathy (DN) los ntawm MAPK taw qhia txoj hauv kev, thiab tawm dag zog tiv thaiv kev ntxhov siab thiab tiv thaiv kab mob.
Related Categories: kev tshawb fawb teb >> mob cancer
Hom phiaj: p38 MAPK
Siv:
[1].Knox K, et al.Lub Coumarin Glucoside, Esculin, nthuav tawm kev hloov pauv sai hauv Phloem-Kev thauj mus los nrawm hauv kev teb rau ib puag ncig cues.Nroj Physiol.2018 Peb Hlis;178(2): 795-807 : kuv.
[2].Song Y, et al.Esculin ameliorates kev paub tsis meej nyob rau hauv kev sim ntshav qab zib nephropathy thiab induces anti-oxidative kev nyuaj siab thiab anti-inflammatory los ntawm txoj kev MAPK.Mol Med Rep. 2018 Tsib Hlis;17(5):7395-7402.
Physicochemical Properties ntawm Esculin
Qhov ceev: 1.7 ± 0.1 g / cm3
Boiling Point: 697.7 ± 55.0 ° C ntawm 760 mmHg
Melting Point: 203 ° C
Cov mis mos molecular: c15h16o9
Molecular Luj: 358.297
Flash Point: 262.8 ± 25.0 ° C
PIB: 358.089996
PSA: 358.089996
LogP:-1.52
Cov tsos mob: cream hmoov
Chav Siab: 0.0 ± 2.3 mmHg ntawm 25 ° C
Refractive Index: 1.689
Kev cia khoom
1 Khaws rau hauv qhov chaw txias, qhuav thiab zoo ventilated warehouse.Khaws kom deb ntawm qhov hluav taws kub thiab qhov chaw kub.Tiv thaiv los ntawm tshav ntuj ncaj qha.Ntim sealing.Nws yuav tsum tau muab cais tawm ntawm cov kua qaub thiab cov tshuaj uas siv tau, thiab tsis pub sib xyaw cia.Lub chaw cia khoom yuav tsum tau nruab nrog cov ntaub ntawv tsim nyog kom muaj cov xau.
2. Argon ntim ntim ntim cia
Kev ruaj ntseg: siv thiab khaws cia raws li qhov tshwj xeeb yam tsis muaj kev puas tsuaj thiab tsis txhob sib cuag nrog oxides
Dej Solubility: qauv soluble
Molecular Structure
1. Molar refractive index: 77.35
2. Molar ntim (cm3 / mol): 202.6
3. Isotonic tshwj xeeb ntim (90.2k): 628.5
4. Nto nro (dyne / cm): 92.6
5. Polarizability (10-24cm3): 30.66
Esculin Safety Information
Hazard code (Tebchaws Europe): F, C, Xi
Nqe Lus Tshaj Tawm (Tebchaws Europe): R11
Daim Ntawv Qhia Txog Kev Nyab Xeeb (Tebchaws Europe): s26-s36 / 37 / 39-s45-s24 / 25
Kev thauj mus los ntawm cov khoom txaus ntshai: UN 2924 3 / PG 2
Wg Germany: 3
RTECS No.: dj3085000
PIB: 294200000
Esculin Kev lis kev cai
Kev lis kev cai Code: 2942000000
English Alias ntawm Esculin
Crataegin
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside
IB 208-517-5
vitamin ua 2
Enallachrome
Esculetin 6-β-D-glucoside
POLYDROM
Bicolorin
Esculetin 6-O-glucoside
Polychrom
7-Hydroxy-2-oxo-2H-chromen-6-yl-β-D-glucopyranoside
BICOLOIN
7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate
Esculin
7-Hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2H-chromen- 2- ib
6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-ib
Esculetin 6-bD-glucoside
2H-1-Benzopyran-2-ib, 6-(β-D-glucopyranosyloxy)-7-hydroxy-
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1: 1)
Aesculin
PAB 00006879
Esculetin-6-O-glucoside
2H-1-Benzopyran-2-ib, 6-(β-D-glucopyranosyloxy)-7-hydroxy-, hydrate (1: 1)
Escosyl
