Fraxetin;Fraxetol;Tom ntej: 7,8-Dihydroxy-6-methoxycoumarin CAS No: 574-84-5
Cov ntsiab lus
Alias:Qinpi Pavilion;Fraxinus lactone
Lub npe Askiv:fraxetin; fraxetol
Nws belongs rau coumarin compounds.Nws yog flake crystal (ethanol), melting point 228 ℃, tig daj ntawm 150 ℃, thiab puv xim av ntawm melting point.Nws yog hydrolyzate ntawm aesculin, soluble nyob rau hauv ethanol thiab hydrochloric acid aqueous tov, me ntsis soluble nyob rau hauv boiling dej thiab insoluble nyob rau hauv ether.
Nws los ntawm Fraxinus brngeana DC Bark, nplooj ntawm F. floribunda phab ntsa, thiab lwm yam.
Nws muaj cov nyhuv ntawm cov kab mob dysentery bacilli thiab yog siv los kho cov kab mob dysentery hauv cov menyuam yaus.
Cov khoom muab fraxetin: Qinpi Pavilion
Khoom Parameter:CAS Nr .: 574-84-5
Cov ntsiab lus zoo (%):98.5%
Daim ntawv thov:kev txiav txim siab cov ntsiab lus, pharmacological reagent, thiab lwm yam
Khoom specification:10 mg, 20 mg, 1 g
Muab fraxetin:Qinpiting, tseem hu ua Fraxinus lactone
Lub npe Askiv:fraxetin;Fraxetol; Fraxexin; Coumarin, 7,8-dihydroxy-6-methoxy-
CAS Nr:574-84-5 : kuv
Ntshiab ntshiab extraction, tom qab NMR qauv kev pom zoo thiab HPLC purity nrhiav kom tau, cov ntsiab lus yog ntau tshaj 98.5%.
Suav alias:7,8-dihydroxy-6-methoxycoumarin English Lub npe: 7,8-dihydroxy-6-methoxycoumarin English alias: EINECS No.: 209-376-2 molecular formula: c10h8o5 molecular hnyav: 208.1675inchi: Inchi = 1/c10h8o -14-6-4-5-2-3-7 (11) 15-10 (5) 9 (13) 8 (6) 12 / h2-4,12-13h, 1h3 ntom: 1.508g/cm boiling point : 472 ° C ntawm 760 mmHg flash point: 196 ° C
Physicochemical Cov Khoom Ntawm Fraxetin
Qhov ceev: 1.5 ± 0.1 g / cm3
Boiling Point: 472.0 ± 45.0 ° C ntawm 760 mmHg
Melting Point: 230-232 ° C
Cov mis mos molecular: c10h8o5
Molecular Luj: 208.167
Flash Point: 196.0 ± 22.2 ° C
Qhov tseeb Mass: 208.037170
PSA: 79.90000
pwm: 0.59
Cov tsos mob: lub teeb daj siv lead ua ntsiav tshuaj
Stability: daj ntseg daj flake siv lead ua, cov xim yuav darker thaum rhuab, thiab ua xim av ze rau lub melting point.Me ntsis soluble nyob rau hauv ether thiab boiling dejLub teeb daj flake siv lead ua tig tsaus thaum rhuab, thiab tig xim av nyob ze ntawm lub melting point.Me ntsis soluble nyob rau hauv ether thiab boiling dej, Nws tshwm xiav-ntsuab nyob rau hauv lub xub ntiag ntawm ferric chloride.Nyob ruaj khov nyob rau hauv ib txwm kub thiab siab.
Computational Chemistry
1. Tus nqi siv rau hydrophobic parameter xam (xlogp): 1.2
2. Tus naj npawb ntawm cov nyiaj pub dawb hydrogen: 2
3. Tus naj npawb ntawm hydrogen bond receptors: 5
4. Number of rotatable chemical bonds: 1
5. Tus naj npawb ntawm tautomers: 16
6. Topological molecular polarity nto thaj tsam 76
7. Tus naj npawb ntawm cov atom hnyav: 15
8. Nto nqi: 0
9. Kev nyuaj siab: 288
10. Tus naj npawb ntawm isotopic atoms: 0
11. Txiav txim seb tus naj npawb ntawm atomic stereocenters: 0
12. Tus naj npawb ntawm cov tsis paub meej atomic stereocenters: 0
13. Txiav txim seb tus naj npawb ntawm cov tshuaj stereocenters: 0
14. Number of indeterminate chemical bond stereocenters: 0
15. Number of covalent bond units: 1
