Obtusin
Kev siv Obtusin
Obtusin, los ntawm cassia noob, yog ib qho kev xaiv thiab kev sib tw inhibitor ntawm tib neeg monoamine oxidase-A (hmao-a), nrog rau IC50 ntawm 11.12 μ M. Ki yog 6.15.Obtusin plays lub luag haujlwm tiv thaiv kab mob neurodegenerative, tshwj xeeb tshaj yog kev ntxhov siab thiab kev nyuaj siab.
Lub npe Obtusin
English Name: Obtusin
Bioactivity ntawm Obtusin
Nqe lus piav qhia: obtusin yog los ntawm cov noob cassia.Nws yog ib qho kev xaiv zoo heev thiab kev sib tw inhibitor ntawm tib neeg monoamine oxidase-A (hmao-a), nrog IC50 ntawm 11.12 μ M. Ki yog 6.15.Obtusin plays lub luag haujlwm tiv thaiv kab mob neurodegenerative, tshwj xeeb tshaj yog kev ntxhov siab thiab kev nyuaj siab.
Related Pawg: teeb liab txoj kev > > neural teeb liab txoj kev > > monoamine oxidase
Kev tshawb fawb teb > > kab mob neurological
Lub hom phiaj: IC50: 11.12 μ M (hMAO-A)[1] Ki: 6.15 (hMAO-A)[1]
References: [1] Paudel P, et al.Hauv Vitro thiab hauv Silico Tib Neeg Monoamine Oxidase Inhibitory Muaj peev xwm ntawm Anthraquinones, Naphthopyrones, thiab Naphthalenic Lactones los ntawm Cassia obtusifolia Linn Seeds.ACS Omega.2019 Sep 18;4(14):16139-16152.
Physicochemical zog ntawm Obtusin
Qhov ceev: 1.4 ± 0.1 g / cm3
Boiling Point: 614.9 ± 55.0 ° C ntawm 760 mmHg
Cov mis mos molecular: c18h16o7
Molecular Luj: 344.315
Flash Point: 227.0 ± 25.0 ° C
PIB: 344.089600
PSA: 102.29000
LogP: 4.10
Chav Siab: 0.0 ± 1.8 mmHg ntawm 25 ° C
Refractive Index: 1.634
Obtusin Safety Information
Kev lis kev cai Code: 2914690090
Cov ntawv nyeem: Cameron, Donald W;Feutrill, Geoffrey I.;Kev twv txiaj, Glenn B.;Stavrakis, John Tetrahedron Letters, 1986, vol.27 Ib., 41.4999-5002 : kuv
Obtusin Customs
Kev lis kev cai Code: 2914690090
Suav Txheej txheem cej luam: Suav txheej txheem cej luam
Summary: 2914690090 lwm yam quinones. Kev saib xyuas tej yam kev mob: Tsis muaj. VAT: 17.0%. Tax rebate rate: 9.0%. MFN tariff: 5.5%. General tariff: 30.0%.
English Alias Of Customs
9,10-Anthracenedione, 1,7-dihydroxy-2,3,8-trimethoxy-6-methyl-
1,7-dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione
1,7-Dihydroxy-2,3,8-trimethoxy-6-methyl-9,10-anthraquinone
Khoom Tswjhwm Zoo
1. Lub tuam txhab yuav nuclear magnetic resonance (Bruker 400MHz) spectrometer, kua theem huab hwm coj spectrometer (LCMS), roj theem huab hwm coj spectrometer (GCMs), huab hwm coj spectrometer (dej SQD), ntau yam tsis siv neeg analytical siab ua kua chromatographs, npaj kua chromatographs, thiab lwm yam .
2. Lub tuam txhab tuav kev koom tes zoo thiab kev sib cuag nrog cov chaw tshawb fawb tshawb fawb xws li Shanghai Lub Koom Haum rau kev tswj hwm tshuaj, Nanjing biomedical public service platform thiab tsom xam thiab kuaj qhov chaw ntawm Shanghai Pharmaceutical Industry Research Institute.
3. Lub tuam txhab tab tom ua haujlwm ua cov ntawv pov thawj kev kuaj thib peb, thiab xav tias yuav tau txais CNAs Laboratory Accreditation Certificate hauv 2021.
