Paeoniflorin CAS No. 23180-57-6
Cov ntaub ntawv tseem ceeb
Kuj hu ua paeoniflorin, nws yog pinane monoterpene iab glycoside cais los ntawm liab peony thiab dawb peony.Nws yog hygroscopic amorphous hmoov.Nws muaj nyob rau hauv cov hauv paus hniav ntawm Paeonia, peony, ntshav peony thiab lwm yam nroj tsuag ntawm Ranunculaceae.Lub toxicity ntawm no crystal yog tsawg heev.
[chemical npe]5-beta-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1alpha(2H)-yl-beta-D-glucopyranoside
[molecular formula]C23H28O11
【CASTsis muaj】23180-57-6
Purity: siab dua 98%, kev kuaj pom: HPLC.
[qhov chaw]cov hauv paus hniav ntawm Paeonia albiflora pall, P. suffrsticosa Andr, P. delarayi Franch, ib tsob nroj ntawm Ranunculaceae, cov ntsiab lus ntawm radix paeoniae Rubr yog siab tshaj.
[Specification]10%, 20%, 30%, 50%, 90%, 98%
[Aua ctiveIkhoom noj ] Tag nrho cov glucosides ntawm Paeonia (TGP) yog lub npe dav dav ntawm paeoniflorin, hydroxy paeoniflorin, paeoniflorin, albiflorin thiab benzoyl paeoniflorin, uas yog hu ua TGP luv luv.
Lub cev thiab tshuaj muaj zog
Nws yog hygroscopic amorphous Tan hmoov (90% yog tawm dawb hmoov) [α] 16D-12.8. (C = 4.6, methanol), tetraacetate yog xim tsis muaj xim acicular crystal, melting point: 196 ℃.Paeoniflorin ruaj khov nyob rau hauv ib puag ncig acidic (pH 2 ~ 6) thiab tsis ruaj khov nyob rau hauv ib puag ncig alkaline.
Kev txiav txim siab txog cov ntsiab lus
Feem ntau, txoj kev 1 thiab txoj kev 2 kuj tuaj yeem siv rau kev tshawb nrhiav.Txoj Kev 1 yog qhov zoo tshaj plaws siv rau kev tsim cov ntsiab lus siab, uas tuaj yeem pab cov neeg ua haujlwm zoo dua txiav txim siab purity ntawm cov khoom.Cov ntaub ntawv siv tau yooj yim rau decompose tom qab dissolution.
1.Nws tau txiav txim siab los ntawm kev ua haujlwm siab ua kua chromatography (Appendix VI d).Cov kab mob chromatographic thiab kev ua kom haum tau raug sim nrog Octadecyl silane bonded silica gel li muab tub lim;Acetonitrile-0.1% phosphoric acid tov (14:86) tau siv los ua theem mobile;Kev kuaj pom wavelength yog 230nm.Tus naj npawb ntawm cov phaj theoretical xam raws li paeoniflorin ncov yuav tsum tsis pub tsawg tshaj 2000. Kev npaj ntawm kev siv tshuaj: raug ntsuas qhov tsim nyog ntawm cov tshuaj paeoniflorin siv tshuaj thiab ntxiv methanol los npaj 60% paeoniflorin ib 1ml μ G tov.
2.Txhim kho txoj kev txiav txim siab ntawm paeoniflorin hauv Radix Paeoniae Alba.Txoj Kev: Cov txheej txheem hauv Suav Pharmacopoeia thiab cov kev txhim kho tau muab piv.Lub sijhawm txawb yog dej methanol (30:70) thiab qhov ntsuas qhov ntev yog 230nm.tshwm sim;Txoj kev sib raug zoo ntawm txoj kev no yog qhov zoo (r = 0.9995).Qhov nruab nrab rov qab yog 101.518% thiab RSD yog 1.682%.Xaus: txoj kev txhim kho yog qhov yooj yim thiab raug, uas tuaj yeem txo cov toxicity ntawm cov kuab tshuaj organic rau tib neeg thiab ib puag ncig muaj kuab paug, thiab muab lub hauv paus siv rau kev txiav txim siab ntawm paeoniflorin hauv kev xyaum.
Kev txiav txim siab
Kev txiav txim siab ntawm paeoniflorin los ntawm HPLC
Scope ntawm kev siv:Txoj kev no siv HPLC los txiav txim cov ntsiab lus ntawm paeoniflorin hauv Guizhi Fuling tshuaj.
Txoj kev yog tsim rau Guizhi Fuling ntsiav tshuaj.
Txoj ntsiab cai:Muab cov qauv kuaj rau hauv lub khob ntim dej, ntxiv qhov tsim nyog ntawm dilute ethanol rau kev rho tawm ultrasonic, txias nws, co nws zoo, lim nws, cov lim nkag mus rau qhov ua tau zoo ntawm cov kua chromatograph rau chromatographic sib cais, siv lub tshuab nqus ultraviolet kom kuaj xyuas qhov zoo. absorption tus nqi ntawm paeoniflorin ntawm lub wavelength ntawm 230nm, thiab xam nws cov ntsiab lus.
