Products

Biological Activity Of Panaxatriol

Description: Panaxatriol is a natural product, which can reduce the bone marrow inhibition caused by radiation damage.

Related categories: signal path > > other > > other

Research field > > others

Natural Products > > terpenoids and glycosides

Reference: [1]. Liu FY, et al. Effect of panaxatriol on hematogenesis and granulocyte-macrophage colony stimulating factor in radiation injured mice. Saudi Med J. 2007 Dec;28(12):1791-5.

Physicochemical Properties Of Panaxatriol

Density: 1.1 ± 0.1 g / cm3

Boiling point: 561.5 ± 50.0 ° C at 760 mmHg

Molecular Formula: C30H52O4

Molecular Weight: 476.732

Flash Point: 293.4 ± 30.1 ° C

Accurate Mass: 476.386566

PSA: 69.92000

LogP: 5.94

Vapor Pressure: 0.0 ± 3.5 mmHg at 25 ° C Refractive Index: 1.527

1. Properties: white powder (ethanol n-butanol).

2. Density (g / ml, 20 ℃): undetermined

3. Relative vapor density (g / ml, air = 1): not determined

4. Melting point (º C): 192 ~ 194 ℃ (decomposition), 199 ~ 201 ℃

5. Boiling point (º C, atmospheric pressure): not determined

6. Boiling point (º C, kPa): not determined

7. Refractive index: undetermined

8. Flash point (º C): not determined

9. Specific rotation (º, C = 1.03, methanol): + 1.93

10. Spontaneous combustion point or ignition temperature (º C): not determined

11.Vapor pressure (PA, 20 º C): not determined

12. Saturated vapor pressure (kPa, 20 º C): not determined

13. Heat of combustion (kJ / mol): not determined

14. Critical temperature (º C): not determined

15. Critical pressure (kPa): not determined

16. Logarithm of oil-water (octanol / water) partition coefficient: not determined

17. Upper explosion limit (%, V / V): not determined

18. Lower explosive limit (%, V / V): not determined

19. Solubility: not determined

Preparation of Panaxatriol

Under the action of dilute acid, the hydroxyl group of the side chain of protopanaxatriol molecule of ginsenoside Rg in ginseng is cyclized with ene bond to produce Panaxatriol. It exists in the roots, stems and leaves of Panax ginseng and the roots of American ginseng.

English Alias of Panaxatriol

(20R)-Panaxatriol
Panoxatriol
Dammarane-3,6,12-triol, 20,25-epoxy-, (3β,6β,12β,20R)-
Panaxatriol
DAMMARANE-3BETA,6BETA,12BETA-20,25-EPOXYTRIOL
PANAXADIOL(SH)
Panaxtriol
HYDROXYPANAXIDIOL
(3β,6β,12β,20R)-20,25-Epoxydammarane-3,6,12-triol