Orientin
Aplikasyon Orientin
Orientin se yon flavonoid bioaktif natirèl ak yon varyete de karakteristik byolojik, ki gen ladan anti-enflamatwa, antioksidan, anti-timè, pwoteksyon kè ak sou sa.Orientin se yon ajan neuroprotective pwomèt, ki apwopriye pou tretman doulè neropatik.
Byoaktivite nan Orientin
Deskripsyon:orientin se yon flavonoid byoaktif natirèl ak yon varyete de karakteristik byolojik, ki gen ladan anti-enflamatwa, antioksidan, anti-timè, pwoteksyon kè ak sou sa.Orientin se yon ajan neuroprotective pwomèt, ki apwopriye pou tretman doulè neropatik.
Kategori ki gen rapò:domèn rechèch > > kansè
Chemen siyal >> lòt >> lòt
Domen rechèch > > maladi newolojik
Rreferans:[1].Dhakal H, et al.Efè inhibition nan orientin nan enflamasyon alèjik mast selil-medyatè.Pharmacol Rep. 24 janvye 2020.
[2].Guo D, et al.Orientin ak doulè neropatik nan rat ak ligasyon nè epinyè.61Int Immunopharmacol.2018 Me;58:72-79.
Pwopriyete fizikochimik nan Orientin
Dansite: 1.8 ± 0.1 g / cm3
Pwen bouyi: 816.1 ± 65.0 ° C nan 760 mmHg
Pwen k ap fonn: 260-285 º C
Fòmil molekilè: C21H20O11
Pwa molekilè: 448.377
Flash Point: 289.1 ± 27.8 ° C
Mass egzat: 448.100555
PSA: 201.28000
LogP: 1.58
Aparans: poud jòn
Presyon vapè: 0.0 ± 3.1 mmHg nan 25 ° C
Endèks refraktif: 1.767
Solibilite dlo: 1 M
NaOH: soluble 1mg / ml, klè, jòn zoranj
Digitalis enfòmasyon sekirite
Deklarasyon sekirite (Ewòp): 24 / 25
Kòd transpò machandiz danjere: nonh pou tout mòd transpò RTECS号:DJ3009300
Revizyon literati nan Orientin
Distenksyon nan pè izomè C-glycosylflavone orientin/isoorientin ak vitexin/isovitexin lè l sèvi avèk HPLC-MS mezi egzak mas ak nan-sous CID.
Phytochem.Anal.16(5), 295-301, (2005)
HPLC-MS lè l sèvi avèk kolizyon pwovoke dissociation (CID) yo te itilize pou idantifikasyon nan pè izomè C-glycosylflavone orientin / isoorientin ak vitexin / isovitexin.HPLC-CID/MS analize prod..
Efè antiipèrtansif ak kadyopwotektif nan fwi Lagenaria siceraria nan NG-nitro-L-arginine methyl ester (L-NAME) pwovoke rat ipèrtansif.
Pharm.Biol.50(11), 1428-35, (2012)
Lagenaria siceraria (Molina) Standl.Yo rapòte (Cucurbitacae) (LS) genyen aktivite kadyopwotektif, antiiperlipidemi, ak dyurèz. Pou evalye efè antiipètansif ak kadyopwotektif...
Devlopman ak validation yon metòd HPTLC pou kantite similtane isoorientin, isovitexin, orientin, ak vitexin nan flavonoid fèy banbou.
J. AOAC Ent.93(5), 1376-83, (2010)
Yon metòd HPTLC senp yo te devlope pou detèminasyon an similtane nan isoorientin, isovitexin, orientin, ak vitexin, tou de pi ak nan echantiyon komèsyal nan flavonoid fèy banbou.Flavon an...
Angle alyas nan Orientin
(1S)-1,5-Anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-D-glucitol
2-(3,4-Dihydroxyphényl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran- 2-yl]-4H-chromen-4-yonn
Orientin 8-C-β-D-glucopyranoside
3',4',5,7-tetrahydroxyflavone-8-C-glucoside
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran- 2-yl]-4H-chromen-4-on
Luteolin-8-C-glucoside
3',4',5,7-tetrahydroxyflavone 8-glucoside
4H-1-Benzopyran-4-yon, 2-(3,4-dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-
D-Glucitol, 1,5-anhydro-1-C-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-8-yl]-, (1S) -
Orientin
lutexin
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran- 2-yl]-4H-chromen-4-yonn
2-(3,4-Dihydroxyphenyl)-8-bD-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-yon
