Ngwaahịa

Chlorogenic acid nwere ọtụtụ ọrụ dị ndụ.Nnyocha e mere banyere ọrụ chlorogenic acid na sayensị ọgbara ọhụrụ abanyela n'ọtụtụ mpaghara, dịka nri, nlekọta ahụike, ọgwụ, ụlọ ọrụ kemịkalụ kwa ụbọchị na ihe ndị ọzọ.Chlorogenic acid bụ ihe dị mkpa bioactive, nke nwere ọrụ nke antibacterial, antiviral, na-abawanye leukocyte, na-echebe imeju na gallbladder, mgbochi tumor, ibelata ọbara mgbali, iweda ọbara lipid, scavenging free radicals na-akpali akpali Central ụjọ usoro.

Antibacterial na antiviral
Eucommia ulmoides chlorogenic acid nwere mmetụta antibacterial siri ike na mgbochi mkpali, aucubin na polymers ya nwere mmetụta antibacterial doro anya, na aucubin nwere mmetụta mgbochi na gram-adịghị mma na nje bacteria dị mma.Aucubin nwere mmetụta bacteriostatic na diuretic, ma nwee ike ịkwalite ọgwụgwọ ọnya;Aucubin na glucoside nwekwara ike mepụta mmetụta antiviral doro anya mgbe ọdịnala mbụ gasịrị, mana ọ nweghị ọrụ mgbochi.The Institute of ịka nká Medical Sciences, Aichi Medical University, ekwenyela na ihe alkaline amịpụtara na Eucommia ulmoides Oliv.Nwere ikike ibibi nje usoro ahụ ji alụso ọrịa ọgụ.Enwere ike iji ihe a gbochie na ịgwọ ọrịa AIDS.

Antioxidation
Chlorogenic acid bụ antioxidant phenolic dị irè.Ike antioxidant ya siri ike karịa caffeic acid, p-hydroxybenzoic acid, ferulic acid, syringic acid, butyl hydroxyanisole (BHA) na tocopherol.Chlorogenic acid nwere mmetụta antioxidant n'ihi na ọ nwere ụfọdụ radical R-OH, nke nwere ike ịmepụta hydrogen radical na mmetụta antioxidant, ka ikpochapụ ọrụ nke hydroxyl radical, superoxide anion na ndị ọzọ free radicals, iji chebe anụ ahụ si oxidative. mmebi.

Free radical scavenging, mgbochi ịka nká, mgbochi musculoskeletal ịka nká
Chlorogenic acid na ihe ndị na-emepụta ya nwere mmetụta na-ekpo ọkụ n'efu karịa ascorbic acid, caffeic acid na tocopherol (vitamin E), nwere ike mebie DPPH free radical, hydroxyl free radical na superoxide anion free radical, ma nwee ike igbochi oxidation nke obere njupụta. lipoprotein.Chlorogenic acid na-arụ ọrụ dị mkpa n'ịkwụsị radicals n'efu, na-edobe usoro na ọrụ nkịtị nke mkpụrụ ndụ ahụ, na-egbochi ma na-egbu oge ihe omume nke mutation na ịka nká.Eucommia chlorogenic acid nwere ihe pụrụ iche nke nwere ike ịkwalite njikọ na decomposition nke collagen na akpụkpọ ahụ mmadụ, ọkpụkpụ na akwara.Ọ nwere ọrụ nke ịkwalite metabolism na igbochi ọdịda.Enwere ike iji ya gbochie mbelata nke ọkpụkpụ na anụ ahụ nke enweghị oke oghere kpatara.N'otu oge ahụ, a chọpụtara na Eucommia chlorogenic acid nwere mmetụta mgbochi free radical doro anya ma na vivo na in vitro.

Mgbochi nke mutation na antitumor
Nnwale ọgwụ ọgbara ọhụrụ egosila na Eucommia ulmoides chlorogenic acid nwere mmetụta nke mgbochi ọrịa kansa na mgbochi ọrịa kansa.Ndị ọkà mmụta Japan amụwo antimutagenicity nke Eucommia ulmoides chlorogenic acid wee chọpụta na mmetụta a metụtara ihe mgbochi mutagenic dị ka chlorogenic acid, na-ekpughe mkpa chlorogenic acid dị na mgbochi tumor.
Polyphenols na akwụkwọ nri na mkpụrụ osisi, dị ka chlorogenic acid na caffeic acid, nwere ike igbochi mutagenicity nke carcinogens aflatoxin B1 na benzo [a] - pyrene site na igbochi enzymes arụ ọrụ;Chlorogenic acid nwekwara ike nweta mmetụta mgbochi ọrịa kansa na mgbochi ọrịa kansa site na ibelata ojiji nke carcinogens na njem ha na imeju.Chlorogenic acid nwere mmetụta mgbochi dị ịrịba ama na ọrịa cancer colorectal, ọrịa imeju na ọrịa cancer laryngeal.A na-ewere ya dị ka ihe nchebe kemịkal dị irè megide ọrịa kansa.

Mmetụta nchebe na usoro obi obi
Dị ka onye na-ekpochapụ radical free na antioxidant, chlorogenic acid ka egosipụtara site na ọnụ ọgụgụ dị ukwuu nke nnwale.Ọrụ ndu nke chlorogenic acid nwere ike ichebe sistemu obi.Isochlorogenic acid B nwere mmetụta siri ike n'ịkwalite ntọhapụ nke prostacyclin (PGI2) na mgbochi platelet mkpokọta na oke;Ọnụego mgbochi nke mwepụta SRS-A nke mgbochi mmadụ butere irighiri ihe nkuume guinea pig bụ 62.3%.Isochlorogenic acid C kwalitekwara ntọhapụ nke PGI2.Na mgbakwunye, isochlorogenic acid B nwere mmetụta mgbochi siri ike na platelet thromboxane biosynthesis na mmerụ ahụ endothelin nke hydrogen peroxide kpatara.

Mmetụta hypotensive
Achọpụtara ya site na ọtụtụ afọ nke nnwale ụlọ ọgwụ na Eucommia chlorogenic acid nwere mmetụta antihypertensive doro anya, mmetụta ọgwụgwọ kwụsiri ike, adịghị egbu egbu na enweghị mmetụta ọ bụla.Mahadum Wisconsin chọpụtara na ihe ndị dị irè nke Eucommia ulmoides green iji belata ọbara mgbali bụ terpineol diglucoside, aucubin, chlorogenic acid, na Eucommia ulmoides chlorogenic acid polysaccharides.[5]

Ihe omume ndu ndị ọzọ
N'ihi na chlorogenic acid nwere mmetụta mgbochi pụrụ iche na hyaluronic acid (HAase) na glucose-6-phosphatase (gl-6-pase), chlorogenic acid nwere mmetụta ụfọdụ na ọgwụgwọ ọnya, ahụike anụ ahụ na wetting, nkwonkwo mmanu mmanu, na-egbochi mbufụt na nhazi nhazi nke glucose ọbara n'ime ahụ.Chlorogenic acid nwere mmetụta mgbochi siri ike na igbu ọchụ na ọrịa dị iche iche na nje.Chlorogenic acid nwere mmetụta ọgwụ na-ebelata ọbara mgbali, antibacterial, antiviral, mgbochi mkpali, ịba ụba ọbara ọcha, igbochi ọrịa shuga, ịba ụba nke eriri afọ na ịkwalite secretion gastric.Nnyocha e mere egosiwo na acid chlorogenic nke ọnụ nwere ike kpalie nzuzo nke bile ma nwee mmetụta nke ịba uru gallbladder na ichebe imeju;Ọ nwekwara ike igbochi hemolysis nke oke erythrocytes nke H2O2 kpatara.