Neohesperidin
Ngwa nke Synephrine Hydrochloride
Neohesperidin bụ ụdị flavonoid compound nke dị n'ọtụtụ ebe na osisi Cucurbitaceae ma nwee mmetụta antioxidant na mgbochi mkpali./h2>
Aha Neohesperidin
English aha: neohesperidin
Utu aha Chinese: neohesperidin |neohesperidin
Bioactivity nke Neohesperidin
Nkọwa: neohesperidin bụ ngwakọta flavonoid dị na Cucurbitaceae, nke nwere mmetụta antioxidant na mgbochi mkpali.
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ubi nyocha > > mbufụt / mgbochi
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N'ime Vitro Ọmụmụ:
Hesperidin ọhụrụ na-ebute apoptosis n'ime mkpụrụ ndụ cancer ara mmadụ MDA-MB-231.Ụkpụrụ IC50 nke neohesperidin na 24 na 48 awa bụ 47.4 ± 2.6, n'otu n'otu μ M na 32.5 ± 1.8 μ M. Okwu p53 na Bax bụ nke a na-achịkwa nke ọma na neohesperidin sel, ebe okwu nke Bcl-2 dị ala. na-achịkwa [1].Neohesperidin gosipụtara ọrụ antioxidant na DPPH radical scavenging test (IC50 = 22.31 μg/ml)[2].
Na Ọmụmụ Vivo: neohesperidin (50mg / kg) na-egbochi nke ọma 55.0% HCl / ethanol butere mmerụ ahụ gastric.N'ime oke pylorus ligated, neohesperidin (50 mg / kg) belatara secretion nke afọ na mmepụta acid gastric na mmụba pH [1].Ọgwụ Neohesperidin belatara nke ukwuu n'ọbara glucose ọbara, glucose ọbara na protein glycosylated serum (GSP) na ụmụ oke.Ọ mụbara nke ukwuu nnabata glucose ọnụ na mmetụta insulin, ma belata nguzogide insulin na ụmụ oke nwere ọrịa shuga.Neohesperidin belatara nke ukwuu serum triglycerides, mkpokọta cholesterol, ọkwa leptin na ndepụta imeju na ụmụ oke [3].
Nnwale anụmanụ: ụmụ oke: ụmụ oke niile na-ebu ọnụ awa 6 tupu ule ahụ, wee nye ya mmiri ma ọ bụ neohesperidin nri site na inye nri mmanye.Maka OGTT na ITT, a gbanyere ụmụ oke na intraperitoneal na 2G / kg BW glucose ma ọ bụ 1iu / kg BW insulin, n'otu n'otu.A na-anakọta ihe nlele ọbara site na vein caudal iji tụọ ọkwa glucose ọbara basal (nkeji 0) tupu ịgbanye glucose ma ọ bụ insulin.A tụrụ ọkwa glucose ọbara ndị ọzọ na nkeji 30, 60, 90 na 120 [3].
Ntụaka:[1].Lee JH, et al.Mmetụta nchebe nke neohesperidin na poncirin dịpụrụ adịpụ na mkpụrụ nke Poncirus trifoliata na ọrịa afọ nwere ike ime.Phytother Res.2009 Dec; 23 (12): 1748-53 .
[2].Xu F, et al.Neohesperidin na-ebute apoptosis cellular na ara mmadụ adenocarcinoma MDA-MB-231 mkpụrụ ndụ site na ịgbalite Bcl-2/Bax-mediated pathway.Nat Prod Commun.2012 Nov; 7 (11): 1475-8 .
[3].Jia S, et al.Mmetụta hypoglycemic na hypolipidemic nke neohesperidin sitere na Citrus aurantium L. na ụmụ oke KK-A (y) na-arịa ọrịa shuga.Ọrụ nri.2015 Mar; 6 (3): 878-86 .
Njirimara physicochemical nke Neohesperidin
Njupụta: 1.7 ± 0.1 g / cm3
Ebe esi esi: 933.7 ± 65.0 ° C na 760 mmHg
Ebe mgbaze: 239-243ºC
Ụdị ihe omimi: C28H34O15
Arọ molekụla: 610.561
Ebe Flash: 306.7 ± 27.8 Celsius C
Kpọmkwem Mass: 610.189758
PSA: 234.29000
Ihe ndekọ: 2.44
Ọdịdị: 0.0 ± 0.3 mmHg na 25 ° C
Nrụgide Steam: 0.0 ± 0.3 mmHg na 25 Celsius
Ntụgharị ntụgharị: 1.695
Ọnọdụ Nchekwa: 2-8 Celsius
Ozi nchekwa Hesperidin ọhụrụ
Ngwa nchedo onwe onye: anya anya;uwe aka;ụdị N95 (US);ụdị P1 (EN143) respirator filter
Nkwupụta nchekwa (Europe): s22-s24 / 25
Koodu ụgbọ njem nke ngwa ahịa dị ize ndụ: noh maka ụdị ụgbọ njem niile
Germany: 3
Nọmba RTECS: dj2981400
Akwụkwọ Neohesperidin
Ntụle metabolic na ntụgharị ederede nke diploid okpukpu abụọ na diploid citrus rootstock ya (C. junos cv. Ziyang xiangcheng) na-egosi uru ọ nwere maka nkwalite nguzogide nrụgide.
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A na-echekarị polyploidy ka ọ na-enye ihe ọkụkụ ka ọ bụrụ mgbanwe ka mma na nrụgide gburugburu ebe obibi.A na-atụ anya na mkpụrụ osisi citrus Tetraploid ga-enwe nnabata nrụgide siri ike karịa diploid.Ọtụtụ...
Ougan (Citrus reticulata cv. Suavissima) flavedo wepụ na-ebelata ọrịa cancer site na itinye aka na mgbanwe epithelial-to-mesenchymal na sel SKOV3.
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Ougan (Citrus reticulata cv. Suavissima) flavedo wepụ (OFE) gosipụtara mmetụta mgbochi tumor nwere usoro ndị na-edoghị anya.Ihe omumu a bu n'obi inyocha ihe nwere ike ime ihe mgbochi metastatic acti...
Hesperidin, nobiletin, na tangeretin na-ahụ maka ikike mgbochi neuroinflammatory nke peel tangerine (Citri reticulatae pericarpium).
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Mgbochi microglial activation-mediated neuroinflammation aghọwo ihe na-ekwenye ekwenye maka mmepe nke nri na-arụ ọrụ iji gwọọ ọrịa neurodegenerative.Osisi tangerine (Citri reticulata ...
Asụsụ Bekee nke Neohesperidin
HESPERETIN-7-NEOHESPERIDOSIDE
Hesperetin7-neohesperidoside
4H-1-Benzopyran-4-otu, 7-[[2-O- (6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl] oxy]-2,3-dihydro-5-hydroxy-2 (3-hydroxy-4-methoxyphenyl) -, (2S)
(2S) -5-Hydroxy-2- (3-hydroxy-4-methoxyphenyl) -4-oxo-3,4-dihydro-2H-chromen-7-yl 2-O- (6-deoxy-α-L- mannopyranosyl) -β-D-glucopyranoside
hesperetin 7-O-neohesperoside
Neohesperdin
Neohesperdin
MFCD00017357
Hesperetin-7-O-neohesperidoside
EINECS 236-216-9
(S) -4'-Methoxy-3',5,7-trihydroxyflavanone-7-[2-O- (α-L-rhamnopyranosyl)-β-D-glucopyranoside]
4H-1-Benzopyran-4-otu, 2,3-dihydro-7-(2-O- (6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl) oxy) -5-hydroxy-2 (3-hydroxy-4-methoxyphenyl) -, (S)
Hesperetin 7-O-neohesperidoside
