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Ngwaahịa

Obtusin

Nkọwa dị mkpirikpi:

Aha nkịtị: cassia

Asụsụ Bekee: obtusin

Nọmba CAS: 70588-05-5

Arọ Molecular: 344.315

Ebe esi mmiri: 614 ± 0.4 MMG / 0.4 CMAT

Ụdị ihe omimi: C18H16O7

Ebe mgbaze: 614.9 ± 55.0 ° C na 760 mmHg

MSDS: N/A

Ebe Flash: 227.0 ± 25.0 Celsius


Nkọwa ngwaahịa

Mkpado ngwaahịa

Ojiji nke Obtusin

Obtusin, sitere na mkpụrụ osisi cassia, bụ onye na-ahọrọ oke na asọmpi na-egbochi mmadụ monoamine oxidase-A (hmao-a), yana IC50 nke 11.12 μ M. Ki bụ 6.15.Obtusin na-arụ ọrụ mgbochi na ọrịa neurodegenerative, karịsịa nchegbu na ịda mbà n'obi.

Aha nke Obtusin

Asụsụ Bekee: Obtusin

Bioactivity nke Obtusin

Nkọwa: obtusin sitere na mkpụrụ cassia.Ọ bụ oke nhọrọ na asọmpi asọmpi nke mmadụ monoamine oxidase-A (hmao-a), na IC50 nke 11.12 μ M. Ki bụ 6.15.Obtusin na-arụ ọrụ mgbochi na ọrịa neurodegenerative, karịsịa nchegbu na ịda mbà n'obi.

Udi emetụtara: Ụzọ mgbama > > Ụzọ mgbama akwara > > monoamine oxidase

Mpaghara nyocha > > ọrịa akwara ozi

Ebumnuche: IC50: 11.12 μ M (hMAO-A) [1] Ki: 6.15 (hMAO-A)[1]

Ntụaka: [1] Paul P, et al.Na Vitro na na Silico Human Monoamine Oxidase Inhibitory ike nke Anthraquinones, Naphthopyrones na Naphthalenic Lactones sitere na Cassia obtusifolia Linn Mkpụrụ.ACS Omega.2019 Septemba 18;4 (14): 16139-16152 .

Njirimara physicochemical nke Obtusin

Njupụta: 1.4 ± 0.1 g / cm3

Ebe esi esi: 614.9 ± 55.0 ° C na 760 mmHg

Ụdị ihe omimi: c18h16o7

Arọ Molecular: 344.315

Ebe Flash: 227.0 ± 25.0 Celsius

Ọnụ ọgụgụ nkịtị: 344.089600

PSA: 102.29000

Ihe ndekọ: 4.10

Nrụgide Steam: 0.0 ± 1.8 mmHg na 25 Celsius

Ntụgharị ntụgharị: 1.634

Ozi nchekwa Obtusin

Koodu mpaghara:: 2914690090

Akwụkwọ: Cameron, Donald W;Feutrill, Geoffrey I.;Ịgba chaa chaa, Glenn B.;Stavrakis, John Tetrahedron Akwụkwọ ozi, 1986, vol.27, # 41 p.4999-5002

Obtusin kọstọm

Koodu mpaghara:: 2914690090

Nchịkọta ndị China: nyocha ndị China

Nchịkọta: 2914690090 quinones ndị ọzọ. Ọnọdụ nlekọta: Ọ dịghị. VAT: 17.0%

Asụsụ Bekee nke kọstọm

9,10-Anthracenedione, 1,7-dihydroxy-2,3,8-trimethoxy-6-methyl-

1,7-dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione

1,7-Dihydroxy-2,3,8-trimethoxy-6-methyl-9,10-anthraquinone

Njikwa ogo ngwaahịa

1. Ụlọ ọrụ zụrụ nuklia magnetik resonance (Bruker 400MHz) spectrometer, mmiri mmiri frasi mass spectrometer (LCMS), gas frasi mass spectrometer (GCMs), uka spectrometer (mmiri SQD), multiple akpaka analytical elu arụmọrụ mmiri chromatographs, preparative mmiri mmiri chromatographs, wdg .

2. Ụlọ ọrụ ahụ na-akwado nkwado na kọntaktị na ụlọ ọrụ nyocha sayensị dị ka Shanghai Institute maka njikwa ọgwụ, Nanjing biomedical public service platform and analysis and test center of Shanghai Pharmaceutical Industry Research Institute.

3. Ụlọ ọrụ ahụ na-arụsi ọrụ ike na-eme asambodo nyocha ụlọ nyocha nke atọ, ma na-atụ anya inweta Asambodo nzere nzere CNAs na 2021.


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