Platycodin D CAS Nọmba 58479-68-8
Ozi dị mkpa
Isi mmalite mmịpụta:Platycodon grandiflorum (Jacq.) A.DC.Mgbọrọgwụ nkụ.
Ụdị nchọpụta:HPLC ≥ 98%.
Nkọwapụta:20mg, 50mg, 100mg, 500mg, 1g (nwere ike ngwugwu dị ka ahịa chọrọ).
agwa:Ọ bụ ọcha crystalline ntụ ntụ.
Ebumnuche:Ejiri ya maka ikpebi ọdịnaya.
Ọnwụ na ihicha:≤2%
Ịdị ọcha:95%, 98%, 99%
Usoro nyocha:HPLC-DAD (ma ọ bụ / na ＾ HPLC-ELSD).
Ụzọ njirimara:Mass spectrometry (mass), resonance magnetik (NMR)
Nchekwa:mechie ma chebe ya pụọ na ìhè, - 20 ℃.
Mkpachapụ anya:Ekwesịrị ịchekwa ngwaahịa a na obere okpomọkụ ma kpọọ nkụ.Ekwesịrị ịchekwa ngwaahịa pụrụ iche n'okpuru nitrogen.Ọ bụrụ na echekwaghị ya ogologo oge, ọdịnaya ga-ebelata.
Nkwenye:afọ 2
Ọ nwere ike izute ọnụ ọgụgụ buru ibu nke ihe a chọrọ n'elu ọkwa gram.Biko kpọtụrụ maka nkọwa.
Bioactivity nke Platycodin D
Nkọwa:platycodin D bụ saponin dịpụrụ adịpụ site na mkpịrị osisi oroma, nke bụ AMPK α Ọ nwere ọrụ mgbochi oke ibu.
Ejikọtara yaCụlọ akwụkwọ:ụzọ akara > > epigenetics > > AMPK
Ụzọ mgbama > > PI3K / Akt / mTOR ụzọ mgbama > > AMPK
Mpaghara nyocha > > ọrịa metabolic
Ebumnuche:AMPK α [1]
Ntụaka:[1] Kim HL, et al.Platycodin D, onye na-eme ihe ọhụụ nke protein kinase na-arụ ọrụ AMP, na-ebelata oke ibu na ụmụ oke db / db site na nhazi nke adipogenesis na thermogenesis.Phytomedicine.2019 Jenụwarị;52:254-263.
Njirimara physicochemical nke Platycodin D
Njupụta:1.6 ± 0.1 g / cm3
Usoro ihe omimi:c57h92o28
Arọ molikula:1225.324
Kpọmkwem oke:1224.577515
PSA:453.28000
LogP:-0.69
Ndekọ ntụgharị uche:1.659
