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Description: isoliquitin is isolated from licorice root and can inhibit angiogenesis and catheter formation. Isoliquitin also has antidepressant effect and antifungal activity.

Related Categories: research field > > infection

Signaling pathway > > anti infection > > fungi

Research field > > inflammation / immunity

Research field > > neurological diseases

Reference:

[1].  Kobayashi S, et al. Inhibitory effect of isoliquiritin, a compound in licorice root, on angiogenesis in vivo and tube formation in vitro. Biol Pharm Bull. 1995 Oct; 18(10):1382-6.

[2].  Wang W, et al. Antidepressant-like effects of liquiritin and isoliquiritin from Glycyrrhiza uralensis in the forced swimming test and tail suspension test in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jul 1; 32(5):1179-84.

[3].  Luo J, et al. Antifungal Activity of Isoliquiritin and Its Inhibitory Effect against Peronophythora litchi Chen through a Membrane Damage Mechanism. Molecules. 2016 Feb 19; 21(2):237.
 Physicochemical Properties Of Isoliquiritin
Density: 1.5 ± 0.1 g / cm3
Boiling Point: 743.5 ± 60.0 ° C at 760 mmHg
Melting Point: 185-186 º C
Molecular Formula: c21h22o9
Molecular Weight: 418.394
Flash Point: 263.3 ± 26.4 ° C
Exact Mass: 418.126373
PSA:156.91000
LogP:0.76
Steam Pressure: 0.0 ± 2.6 mmHg at 25 ° C
Refractive Index: 1.707
English Alias Of Isoliquiritin
2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-, (2E)-

Isoliquiritin

(E)-1-(2,4-dihydroxyphenyl)-3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-en-1-one

3-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-(β-D-glucopyranosyloxy)phenyl)-, (2E)-

4-[(1E)-3-(2,4-Dihydroxyphenyl)-3-oxo-1-propen-1-yl]phenyl β-D-glucopyranoside