Ophiopogonin D Cas No.945619-74-9
Ophiopogon Saponin D Nomen
Nomen anglicum:(1->2)-[β-D-xylopyranosyl-(1->3)] -6-deoxy-β-D-galactopyranoside
Bioactivity of Ophiopogon Japonica Saponin D
Descriptio:Ophiopogon D rara naturalis C29 glycosidis steroidalis solitaria a tuber ophiogoni japonico.Ophiopogonin D inductor est CYP2J3 qui auget CYP2J2 / eets et PPAR in venae umbilicalis humanae cellulis endothelialibus (HUVECs) α Expressio Ang II insigniter inhibita Ang II inducta NF- κ B Translocatio nuclearis, I κ B α Dispositio Dunensis, intracellularis Ca2 + onerare et activation of proinflammatory cytokines.Ophiopogonin D inflammationem et morbos cardiovasculares per milia annorum tractare solebat.
Pertinet Categories
> > > > > > > > > > > calcium
Investigationes campi > > morbus cardiovascularis
Signans iter > > cyclum cellum / DNA damnum > > PPAR
Investigationes campi > > inflammatio / immunitas
Target
PPARα
NF-κB
Ca2+
Documenta Relatio:[1].Wang L, et al.Homo-aro-cholestane, furostane et spirostane saponinus ex tubers Ophiopogonjaponici.Physica.2017 Apr;136:125-132.
[2].Huang X, et al.Ophiopogonin D et EETs ameliorate Ang II responsa inflammationes inducunt per activum PPAR in HUVECs.Biochem Biophys Res Communis.2017 Aug 19: 490 (2):123-133.
alias Ophiopogon saponin D
(1->2)-[β-D-xylopyranosyl-(1->3)] -6-deoxy-β-D-galactopyranoside β-D-Galactopyranoside (1β,3β,25R)-3-hydroxyspirosto-5-en-1-yl O-6-deoxy-α-L-mannopyranosyl-(1- >2)-O-[β-D-xylopyranosyl-(1->3)]-6-deoxy-
(2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-5-hydroxy-2-(((4R,5'R,6R,6aR,6bS,8aS ,8bR,9S,10R,11aS,12aS,12bS) -4-hydroxy-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a; 6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5] indeno[2,1-b] furan-10,2 '-pyran]-6-yl)oxy)-6-methyl-4-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro- 2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol.
Ophiopogonin D
Deacetylophiopogonin C
