lithospermic acid
Application Of Lithospermic Acid
Lithospermic acid ((+) - lithospermic acid) is a plant derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza. It has antioxidant and hepatoprotective activities against CCl4 induced acute and in vitro liver injury.
Name of lithospermic acid
Chinese Name：Purple oxalic acid
English Name：
(2S,3S)-4-[(E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxoprop-1-enyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid
Biological Activity Of Lithospermic Acid
Description: lithospermic acid ((+) - lithospermic acid) is a plant derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza. It has antioxidant and hepatoprotective activities against CCl4 induced acute and in vitro liver injury.
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Reference ：[1]. Chan KW, et al. Anti-oxidative and hepatoprotective effects of lithospermic acid against carbon tetrachloride-induced liver oxidative damage in vitro and in vivo. Oncol Rep. 2015 Aug;34(2):673-80.
Physicochemical Properties Of Lithospermic Acid
Density: 1.6 ± 0.1 g / cm3
Boiling point: 862.6 ± 65.0 ° C at 760 mmHg
Molecular formula: C27H22O12
Molecular weight: 538.456
Flash point: 291.3 ± 27.8 ° C
Exact mass: 538.111145
PSA：211.28000
LogP：1.45
Steam Pressure: 0.0 ± 0.3 mmHg at 25 ° C
Refractive Index: 1.745
English Alias of Lithospermic Acid
4-{(E)-2-[1-Carboxy-2-(3,4-dihydroxy-phenyl)-ethoxycarbonyl]-vinyl}-2-(3,4-dihydroxy-phenyl)-7-hydroxy-2,3-dihydro-benzofuran-3-carboxylic acid
5-{(1E)-3-[1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl}-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid
(2S,3S)-4-{(1E)-3-[(1R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl}-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid
3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, (2S,3S)-
Jiangsu Yongjian Pharmaceutical Technology Co., Ltd
Jiangsu Yongjian Pharmaceutical Technology Co., Ltd., established in March 2012, is a high-tech enterprise integrating R & D, production and sales. It is mainly engaged in the production, customization and production process development of active components of natural products, traditional Chinese medicine reference materials and drug impurities. The company is located in China Pharmaceutical City, Taizhou City, Jiangsu Province, including a 5000 square meter production base and a 2000 square meter R & D base. It mainly serves major scientific research institutes, universities and decoction piece production enterprises across the country.
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Advantageous Business Scope Of The Company
1. R & D, production and sales of chemical reference materials of traditional Chinese medicine;
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3. Research on quality standard and process development of traditional Chinese medicine (plant) extract
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