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Low MOQ for Cas No.2254096-98-3 - Obtusin – Yongjian

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We have our own sales team, design team, technical team, QC team and package team. We have strict quality control procedures for each process. Also, all of our workers are experienced in printing field for Cas No.81720-08-3 Rehmannioside D , Cas No.29070-92-6 , vitexin-2″-o-rhamnoside , We have been sincerely looking forward to developing very good cooperative relationships with buyers from at home and abroad for creating a vibrant foreseeable future together.
Low MOQ for Cas No.2254096-98-3 - Obtusin – Yongjian Detail:

Use of Obtusin

Obtusin, from cassia seed, is a highly selective and competitive inhibitor of human monoamine oxidase-A (hmao-a), with an IC50 of 11.12 μ M. Ki is 6.15. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression.

Name of Obtusin

English Name: Obtusin

Bioactivity of Obtusin

Description: obtusin is from cassia seed. It is a highly selective and competitive inhibitor of human monoamine oxidase-A (hmao-a), with IC50 of 11.12 μ M. Ki is 6.15. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression.

Related Categories: signal pathway > > neural signal pathway > > monoamine oxidase

Research field > > neurological diseases

Target: IC50: 11.12 μ M (hMAO-A)[1] Ki: 6.15 (hMAO-A)[1]

References: [1] Paudel P, et al. In Vitro and in Silico Human Monoamine Oxidase Inhibitory Potential of Anthraquinones, Naphthopyrones, and Naphthalenic Lactones from Cassia obtusifolia Linn Seeds. ACS Omega. 2019 Sep 18; 4(14):16139-16152.

Physicochemical properties Of Obtusin

Density: 1.4 ± 0.1 g / cm3

Boiling Point: 614.9 ± 55.0 ° C at 760 mmHg

Molecular Formula: c18h16o7

Molecular Weight: 344.315

Flash Point: 227.0 ± 25.0 ° C

Exact Mass: 344.089600

PSA:102.29000

LogP:4.10

Steam Pressure: 0.0 ± 1.8 mmHg at 25 ° C

Refractive Index: 1.634

Obtusin Safety Information

Customs Code: 2914690090

Literature: Cameron, Donald W; Feutrill, Geoffrey I.; Gamble, Glenn B.; Stavrakis, John Tetrahedron Letters, 1986 , vol. 27, # 41 p. 4999 – 5002

Obtusin Customs

Customs Code: 2914690090

Chinese Overview: Chinese overview

Summary:2914690090 other quinones。 Supervision conditions:None。 VAT:17.0%。 Tax rebate rate:9.0%。 MFN tariff:5.5%。 General tariff:30.0%

English Alias Of Customs

9,10-Anthracenedione, 1,7-dihydroxy-2,3,8-trimethoxy-6-methyl-

1,7-dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione

1,7-Dihydroxy-2,3,8-trimethoxy-6-methyl-9,10-anthraquinone

Product Quality Control

1. The company purchased nuclear magnetic resonance (Bruker 400MHz) spectrometer, liquid phase mass spectrometer (LCMS), gas phase mass spectrometer (GCMs), mass spectrometer (water SQD), multiple automatic analytical high performance liquid chromatographs, preparative liquid chromatographs, etc.

2. The company maintains close cooperation and contact with scientific research institutions such as Shanghai Institute for drug control, Nanjing biomedical public service platform and analysis and testing center of Shanghai Pharmaceutical Industry Research Institute.

3. The company is actively carrying out laboratory third-party testing certification, and is expected to obtain CNAs Laboratory Accreditation Certificate in 2021.


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