Ophiopogonin D Cas No.945619-74-9
Ophiopogon Saponin D Anarana
Anarana anglisy:(1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)] -6-deoxy-β-D-galactopyranoside
Bioactivity ny Ophiopogon Japonicus Saponin D
Famaritana:Ophiopogon D dia glycoside steroidal C29 voajanahary tsy fahita firy natokana avy amin'ny tuber of Ophiopogon japonicus.Ophiopogonin D dia CYP2J3 inducer izay mampitombo CYP2J2 / eets sy PPAR ao amin'ny olombelona umbilical vein endothelial sela (HUVECs) α Ny fanehoana ny Ang II dia nanakana ny Ang II induced NF-κ B nokleary translocation, I κ B α Down regulation, intracellular Ca2 + overload sy fampahavitrihana ny proinflammatoire cytokines.Ophiopogonin D dia nampiasaina hitsaboana areti-maso sy aretim-po mandritra ny an'arivony taona.
Sokajy mifandraika
Lalana famantarana > > fitaterana transmembrane > > fantsona kalsioma
Fikarohana > > aretim-po
Lalana famantarana > > tsingerin'ny sela / fahasimban'ny ADN > > PPAR
Seha-pikarohana > > mamaivay/immunité
Target
PPARα
NF-κB
Ca2+
Taratasy fanondroana:[1].Wang L, et al.Homo-aro-cholestane, furostane ary spirostane saponins avy amin'ny tubers Ophiopogonjaponicus.Phytochemistry.2017 Apr;136:125-132.
[2].Huang X, et al.Ny Ophiopogonin D sy ny EET dia manatsara ny valin'ny areti-mifindra vokatry ny Ang II amin'ny alàlan'ny fampandehanana ny PPARα amin'ny HUVECs.Biochem Biophys Res Commun.19 aogositra 2017; 490(2):123-133.
Anglisy Alias of Ophiopogon saponin D
(1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)] -6-deoxy-β-D-galactopyranoside β-D-Galactopyranoside, (1β,3β,25R)-3-hydroxyspirost-5-en-1-yl O-6-deoxy-α-L-mannopyranosyl-(1- >2)-O-[β-D-xylopyranosyl-(1->3)]-6-deoxy-
(2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-5-hydroxy-2-(((4R,5'R,6R,6aR,6bS,8aS) ,8bR,9S,10R,11aS,12aS,12bS)-4-hydroxy-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a, 6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2 '-pyran]-6-yl)oxy)-6-methyl-4-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro- 2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol
Ophiopogonin D
Deacetylophiopogonin C
