Hyperoside；Hypercin Cas No. 482-36-0
Nga korero mo te rongoa
[ingoa hua] hypericin
[ingoa Ingarihi] Hyperoside
[alias] hyperin, quercetin 3-galactoside, quercetin-3-o-galactoside
[tauira rāpoi] c21h20o12
[taimaha rāpoi] 464.3763
[C as No.] 482-36-0
[whakarōpū matū] flavonoids
[puna] Hypericum perforatum L
[Whakaahuatanga] > 98%
[Safety terminology] 1. Kaua e pupuhi puehu.2.Mehemea he aitua, he whakararu ranei, me rapu wawe te tirotiro hauora (whakaatuhia tana tapanga ki te taea).
[Pharmacological efficacy] Kei te tohatoha whanui te Hypericin.He hua tino nui me te maha o nga mahi a-tinana, penei i te anti-inflammatory, antispasmodic, diuretic, te maremare, te whakaheke toto, te whakaheke cholesterol, te whakauru pūmua, te analgesia o te rohe me te pokapū, me nga paanga tiaki ki te ngakau me nga oko roro.
[Te ahua o te tinana me te matū] Kowhai kowhai kirikiri kirikiri.Ko te rewa ko 227 ~ 229 ℃, me te hurihanga whatu ko - 83 ° (C = 0.2, pyridine).He ngawari te whakarewa ki te waiwaro, te mewaro, te acetone me te pyridine, ka noho pumau i raro i nga tikanga noa.Ka tauhohe ki te paura konupora waikawa pūhaumāota ki te whakaputa here whero, ka tauhohe te ferric chloride ki te matomato, he pai te tauhohenga α- Naphthol.
[Risk terminology] He kino ki te horomia.
Mahi Rongoa
1. Ko te Hypericin he nui te painga o te analgesic o te rohe, he ngoikore ake i te morphine, he kaha ake i te aspirin, me te kore e whakawhirinaki.Ko te Hypericin he momo rongoa hou o te rohe I te wa ano,
2. He pai te whakamarumaru o te Hypericin ki runga i te myocardial ischemia-reperfusion, cerebral ischemia-reperfusion me te mate pukupuku.
3. Ko te Hypericin he tino whai hua anti-inflammatory: i muri i te whakaurunga o te poi huruhuru, ka werohia nga kiore ki te 20mg / kg i ia ra mo nga ra 7, i tino aukati i te tukanga mumura.
4. He kaha antitussive pānga.
5. Whakakotahitanga.
6. Ka whai hua pea te aukati i te aldose reductase ki te aukati i te mate pukupuku mate huka.
Te painga tiaki i runga i te ischemia myocardial
Ka taea e te Hypericin te whakaheke i te tere o te apoptosis o nga cardiomyocytes na te hypoxia reoxygenation, te aukati i te tuku o te lactate dehydrogenase, te whakapai ake i te mahi o te myocardial superoxide dismutase (SOD) i roto i nga kiore me te whara ischemia-reperfusion myocardial, te whakaiti i te hanga o te malondialdehyde (MDA), te aukati i te te whakanui ake o te phosphokinase myocardial (CPK) i roto i te serum, me te whakaiti i te hanganga o te tukariki kore utu me te waikura nitric free radical, Na hei tiaki i te myocardium me te whakaiti i te whara o te cardiomyocyte me te apoptosis cardiomyocyte na te ischemia-reperfusion.
Te painga tiaki i runga i te ischemia cerebral
Ka taea e te Hypericin te aukati i te heke o te ihirangi formazan i roto i nga poro cerebral i muri i te whara o te hypoxia glucose deprivation reperfusion, te whakanui ake i te maha o nga neurons e ora ana i roto i te cortex me te striatum o nga poro cerebral i roto i te waahi ischemic, me te hanga i te morphology o nga neurons kia oti, kia pai te tohatoha.Aukati i te hekenga o nga mahi neuronal na te wharanga reperfusion hypoxia glucose deprivation.Aukati i te heke o nga mahi SOD, LDH me te glutathione peroxidase (GSHPx).Ko tana tikanga he pa ana ki te hamuku tuwhena kore utu, te aukati i te urunga o te Ca2 me te hanga anti lipid peroxide.
Te awe tiaki ki te ate me te mucosa pekiti
He kaha te whakamarumaru o te Hypericin ki te kiko ate me te mucosa pekiti.Ko tana tikanga e pa ana ki te paanga antioxidant, e whakatairanga ana i te hokinga mai o te taumata N0 ki te noa me te whakanui ake i te mahi SOD.
Te whai hua analgesic antispasmodic
I kitea e te rangahau ko te paanga analgesic o te hypericin ka puta ma te whakaiti i te Ca 2 i roto i nga pito nerve mamae.I te wa ano, ka taea e te hypericin te aukati i te urunga o Ca 2 na te nui o te pāhare pāporo, e tohu ana ko te hypericin hoki ka aukati i te awa Ca i roto i te kiko nerve.Kei te whakaaro ano pea ko te hypericin hei aukati i te hongere Ca 2.Ko nga tirohanga haumanu e whakaatu ana he rite te werohanga hypericin ki te atropine i te maimoatanga o te dysmenorrhea tuatahi.Haunga te iti o nga paanga o te moe, karekau he tauhohenga kino penei i te tachycardia, mydriasis me te werawera.He rongoa pai mo te antispasmodic me te analgesic.
Pānga Hypolipidemic
Ka taea e te Hypericin te whakaheke i te TC serum me te whakanui ake i te HDL / TC ōwehenga i roto i nga kiore nui-ngako, e tohu ana ka taea e te hypericin te whakaiti i te cholesterol, te whakahaere i te toto toto, me te whakapai ake i te mahi o te HDL me te SOD serum i roto i nga kiore.Ka taea e tenei paanga te whakaheke i te kino o te superoxide free radical ki te endothelium vascular i roto i te hyperlipidemia, a he pai ki te pirau me te paoho o te lipid peroxide hei tiaki i te endothelium vascular.
Whakanuia te mahi aukati
Ko te Hypericin i nga pota o te 300 mg / kg me te 150 mg / kg i roto i te vivo ka taea te tino aukati i te taupae thymus, te tipu o nga lymphocytes T me te B me te phagocytosis o nga macrophages peritoneal;I te 59 mg / kg, ka tino whakanuihia te tipu o nga lymphocytes T me te B me te phagocytosis o nga macrophages peritoneal.Ko te Hypericin i te horopeta o te 50 ~ 6.25 ml i roto i te vitro ka taea te whakatairanga nui i te tipu o te T me te B lymphocytes me te whakarei ake i te kaha o te T lymphocytes ki te whakaputa i te IL-2;Hypericin i 6.25 g / ml tino nui ake te kaha o te kiore peritoneal macrophages ki te phagocytize neutrophils, mai i 12.5 ki 3.12 μ G / ml tino nui ake te kaha o te kiore peritoneal macrophages ki te tuku No.
Te awe o te paheketanga
Ko te whakahoahoatanga o te hypothalamic pituitary adrenal (HPA) he huringa koiora noa i roto i nga turoro he pouri nui, e tohuhia ana e te nui o te hunanga o te hormone adrenocorticotropic (ACTH) me te cortisol.Ka taea e Hypericin te whakahaere i te mahi o te tuaka HPA me te whakaheke i nga taumata o te ACTH me te corticosterone, kia pai ai te mahi i te mahi antidepressant.
Tarukino Mutu
Ciwujia capsule
Ko te Acanthopanax senticosus capsule he whakaritenga me te Acanthopanax senticosus kakau me te tango rau hei rauemi mata.Ko te waahanga matua ko te flavonoids, ko te hypericin te waahanga kaha o nga rau Acanthopanax senticosus.
Ko nga tohu matua: te whakatairanga i te tohanga toto me te tango i te toto.Ka whakamahia mo te arthralgia o te uma me te mate ngakau na te whakaheke toto.Ko nga tohu ko te mamae o te uma, te mamae o te uma, te paopao, te takawhita, me etahi atu, na te ngoikore o te kiko me te whatukuhu me te whakaheke toto me te Yin.
Xinan capsule
He whakaritenga i mahia mai i te tangohanga rau hawthorn, he nui nga flavonoids, ko te hypericin tetahi o nga waahanga matua.
Nga tohu matua: te whakawhanui i te punaha cardiovascular coronary, te whakapai ake i te tuku toto myocardial me te whakaheke i te lipid toto.Ka whakamahia ki te hamani i te mate ngakau coronary, angina pectoris, te mamae o te uma, te palpitation, te takawhita, etc.
Qiyue Jiangzhi papa
Ko te papa Qiyue Jiangzhi he rongoa rongoa Hainamana tuku iho lipid-whakaheke i te rongoa ma te tango i nga waahanga whai hua o te rongoa Hainamana tuku iho penei i te hawthorn (enucleated) me te Astragalus membranaceus.Ko tetahi o nga waahanga whai hua nui o te hawthorn he flavonoids, he nui te ihirangi hypericin.
Ko nga tohu matua: whakaheke i te toto toto me te whakangawari i nga oko toto.Ka whakamahia hei whakarei ake i te tohanga toto coronary me te whawhai i te arrhythmia me te hyperlipidemia.
Xinxuening papa
Ko te papa Xinxuening he whakareri puhui i mahia mai i nga rongoa Hainamana penei i te hawthorn me te pueraria.Ko Hawthorn te rongoa whai mana o to tatou roopu.Kei roto te waikawa ursolic, Vitexin rhamnoside, hypericin, waikawa citric, me etahi atu, ko te hypericin te waahanga matua.
Ko nga tohu matua: ko te whakatairanga i te rere toto me te tango i nga tuunga toto, te tarai i nga taapiri me te whakaora i te mamae.Ka whakamahia mo te arthralgia o te uma me te vertigo na te whakaheke toto o te ngakau me nga taapiri o te roro, me te mate ngakau coronary, te whakaheke toto, te angina pectoris me te hyperlipidemia.
Yukexin capsule
Ko Yukexin capsule he rongoa rongoa Hainamana tuku iho i hangaia mai i te whakahaunga tawhito, he mea tito mai i te Hypericum perforatum, te kakano jujube mohoao, te kiri Albizzia, Gladiolus me etahi atu rongoa Hainamana tuku iho.Kei roto te nuinga o te hypericin, te quercetin, te quercetin, te waikawa chlorogenic, te waikawa caffeic, te ymaning, te hypericin me etahi atu waahanga.
Ko nga tohu matua: ko te pouri o te hinengaro na te korenga o te qi ate me te ngakau pouri.
