Ophiopogonin D Cas No.945619-74-9
Ophiopogon Saponin D Ingoa
Ingoa Ingarihi:(1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)] -6-deoxy-β-D-galactopyranoside
Te koiora o Ophiopogon Japonicus Saponin D
Whakaahuatanga:Ko te Ophiopogon D he onge C29 steroidal glycoside tūturu i wehea mai i te kōpura o Ophiopogon japonicus.Ko te Ophiopogonin D he CYP2J3 inducer e whakanui ana i te CYP2J2 / eets me te PPAR i roto i te umbilical vein endothelial cell tangata (HUVECs) α Ko te whakapuaki o Ang II i tino whakakorehia te Ang II i te whakawhiti i te karihi NF- κ B, I κ B α raro ture, intracellular Ca2 + te taumaha me te whakahohe i nga cytokines proinflammatory.Kua whakamahia te Ophiopogonin D ki te rongoa i te mumura me nga mate ngakau mo nga mano tau.
Ngā Kāwai Hāngai
Te ara tohu > > kawe whakawhiti > > hongere konupūmā
Te mara rangahau > > mate ngakau
Ara tohu > > huringa pūtau / kino DNA > > PPAR
Te mara rangahau > > te mumura / mate mate
Whainga
PPARA
NF-kB
Ca2+
Tuhinga Tohutoro:[1].Wang L , et al.Homo-aro-cholestane, furostane me spirostane saponins mai i nga kōpura o Ophiopogonjaponicus.Phytochemistry.2017 Apr;136:125-132.
[2].Huang X, et al.Ko te Ophiopogonin D me nga EET te whakapai ake i nga urupare mumura a Ang II ma te whakahohe i te PPARα i roto i nga HUVEC.Biochem Biophys Res Commun.2017 Akuhata 19;490(2):123-133.
Ingoa Ingarihi o Ophiopogon saponin D
(1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)] -6-deoxy-β-D-galactopyranoside β-D-Galactopyranoside, (1β,3β,25R)-3-hydroxyspirost-5-en-1-yl O-6-deoxy-α-L-mannopyranosyl-(1- >2)-O-[β-D-xylopyranosyl-(1->3)]-6-deoxy-
(2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-5-hydroxy-2-(((4R,5'R,6R,6aR,6bS,8aS) ,8bR,9S,10R,11aS,12aS,12bS)-4-hydroxy-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a, 6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2 '-pyran]-6-yl)oxy)-6-methyl-4-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro- 2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol
Ophiopogonin D
Deacetylophiopogonin C
