Ophiopogonin D Cas No.945619-74-9
Ophiopogon Saponin D Dzina
Dzina la Chingerezi:(1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)] -6-deoxy-β-D-galactopyranoside
Bioactivity ya Ophiopogon Japonicus Saponin D
Kufotokozera:Ophiopogon D ndi C29 steroidal glycoside yosowa yachilengedwe yomwe ili kutali ndi tuber ya Ophiopogon japonicus.Ophiopogonin D ndi CYP2J3 inducer yomwe imawonjezera CYP2J2 / eets ndi PPAR m'maselo a umbilical vein endothelial cell (HUVECs) α Kufotokozera kwa Ang II kunalepheretsa Ang II kuchititsa NF- κ B kusuntha kwa nyukiliya, I κ B α Down regulation, intracellular Ca2 + kuchulukitsitsa ndi kuyambitsa kwa proinflammatory cytokines.Ophiopogonin D wakhala akugwiritsidwa ntchito pochiza kutupa ndi matenda amtima kwa zaka zikwi zambiri.
Magulu Oyenera
Njira yolumikizira>> transmembrane transport>> calcium channel
Kafukufuku > > matenda a mtima
Njira yolumikizira>> kuzungulira kwa ma cell / kuwonongeka kwa DNA>> PPAR
Kafukufuku>> kutupa / chitetezo chokwanira
Zolinga
PPARA
NF-kB
Ca2+
Zolemba Zothandizira:[1].Wang L, ndi al.Homo-aro-cholestane, furostane ndi spirostane saponins kuchokera ku ma tubers a Ophiopogonjaponicus.Phytochemistry.2017 Apr; 136:125-132.
[2].Huang X, et al.Ophiopogonin D ndi EETs amathandizira mayankho otupa a Ang II kudzera mu kuyambitsa PPARα mu HUVECs.Biochem Biophys Res Commun.2017 Aug 19; 490 (2): 123-133.
Dzina la Chingerezi la Ophiopogon saponin D
(1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)] -6-deoxy-β-D-galactopyranoside β-D-Galactopyranoside, (1β,3β,25R) -3-hydroxyspirost-5-en-1-yl O-6-deoxy-α-L-mannopyranosyl-(1- >2) -O-[β-D-xylopyranosyl-(1->3)]-6-deoxy-
(2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-5-hydroxy-2-(((4R,5'R,6R,6aR,6bS,8aS) ,8bR,9S,10R,11aS,12aS,12bS)-4-hydroxy-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a, 6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2 '-pyran]-6-yl)oxy)-6-methyl-4-(((2S,3R,4S,5R) -3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro- 2H-pyran-3-yl)oxy) -6-methyltetrahydro-2H-pyran-3,4,5-triol
Ophiopogonin D
Deacetylophiopogonin C
