Platycodin D CAS No. 58479-68-8
Zambiri Zofunikira
Kochokera:Platycodon grandiflorum (Jacq.) A.DC.Mizu youma.
Njira yozindikirira:HPLC ≥ 98%.
Zofotokozera:20mg, 50mg, 100mg, 500mg, 1g (akhoza kuikidwa malinga ndi zofuna za makasitomala).
Khalidwe:Ndi woyera crystalline ufa.
Cholinga:Amagwiritsidwa ntchito pozindikira zomwe zili.
Kutaya pakuyanika:≤ 2%
Chiyero:95%, 98%, 99%
Njira Yowunika:HPLC-DAD ^ kapena / ndi^ HPLC-ELSD
Njira zozindikiritsira:mass spectrometry (mass), nuclear magnetic resonance (NMR)
Posungira:osindikizidwa ndi kutetezedwa ku kuwala, - 20 ℃.
Kusamalitsa:Izi ziyenera kusungidwa pa kutentha otsika ndi youma.Mankhwala apadera ayenera kusungidwa pansi pa nayitrogeni.Ngati sichisungidwa kwa nthawi yayitali, zomwe zili zidzachepetsedwa.
Kutsimikizika:zaka 2
Ikhoza kukwaniritsa zofuna zambiri pamwamba pa mlingo wa gramu.Chonde funsani zambiri.
Bioactivity ya Platycodin D
Kufotokozera:platycodin D ndi mankhwala a saponin omwe amadzipatula ku phesi lalalanje, lomwe ndi AMPK α Lili ndi ntchito yoletsa kunenepa kwambiri.
ZogwirizanaCmagulu:njira yolumikizira>> epigenetics>> AMPK
Njira yolumikizira>> PI3K / Akt / mTOR njira yolumikizira>> AMPK
Gawo lofufuza > > matenda a metabolic
Zolinga:AMPK α [1]
Maumboni:[1] Kim HL, et al.Platycodin D, woyambitsa buku la AMP-activated protein kinase, amachepetsa kunenepa kwambiri mu mbewa za db/db kudzera pakuwongolera adipogenesis ndi thermogenesis.Phytomedicine.2019 Jan;52:254-263 .
Physicochemical Properties ya Platycodin D
Kachulukidwe:1.6 ± 0.1 g / cm3
Molecular formula:c57h92o28
Kulemera kwa mamolekyu:1225.324
Misa yeniyeni:1224.577515
PSA:453.28000
LogP:-0.69
Refractive index:1.659