Vitexin;Apigenin8-C-glucoside CAS No. 3681-93-4
Zambiri Zofunikira
Dzinali:apigenin8-c-glucoside
Dzina la Chemical:8- β- D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl) -4H-1-benzopyran-4-one
Molecular formula:c21h20o10 kumwetulira kovomerezeka: C1 = CC (= CC = C1C2 = CC (= O) C3 = C (O2) C (= C (C = C3O) o) C4C (C (C (O4) co) o) o) o
Kulemera kwa mamolekyu:432.3775
Nambala ya CAS:3681-93-4
Zakuthupi ndi Zamankhwala
Maonekedwe:ufa wachikasu
Gwero:Craeagus pinnatifida, chomera cha Rosaceae, chili ndi zipatso zouma komanso zokhwima.
Kugwiritsa ntchito
Chifukwa chake, zopangira zamasamba oyera a Vitex ndi mbewu za Vitex ndizosowa, ndipo masamba osonkhanitsidwa a Vitex amagwiritsidwa ntchito kusungunula ndi kuyeretsa mafuta a Vitex, zomwe zimatsogolera opanga zotulutsa mbewu kusiya zoyambira ndikuchotsa Vitexin.M'malo mwake, amagwiritsa ntchito masamba a hawthorn kuchotsa Vitexin, kuchotsa Vitexin kuchokera ku flavonoids yonse ya Masamba a Hawthorn kudzera m'zigawo, kupatukana, kuyeretsa ndi njira zina, ndipo potsiriza amapanga kukonzekera kowuma.
Vitexin imagwiritsidwa ntchito kwambiri pochiza matenda amtima.Kuyera kwa Vitexin nthawi zambiri kumafunika kukhala> 98% (HPLC).Vitexin ya jekeseni yakhala ikugwiritsidwa ntchito kuchipatala.Ntchito zazikulu za Vitexin ndikulimbikitsa kuyenda kwa magazi ndikuchotsa kukhazikika kwa magazi, kuwongolera qi ndi kugunda kwamtima.Amagwiritsidwa ntchito potsekereza pachifuwa chifukwa cha kukhazikika kwa magazi.Zizindikiro zake ndi kutsekeka pachifuwa, kufupikitsidwa, kumva kulasalasa m'dera losakhazikika, palpitation, kuyiwala, chizungulire ndi tinnitus.Matenda a mtima, angina pectoris, hyperlipidemia, magazi osakwanira a mitsempha ya mtima ndi zizindikiro zina.
Matenda a mtima ndi cerebrovascular ndi matenda ofala kwambiri mwa anthu, ndipo akhala omwe amayambitsa kufa kwakukulu padziko lonse lapansi.Malinga ndi kuyerekezera kwa WHO, matenda amtima ndi cerebrovascular amapha pafupifupi 12 miliyoni padziko lonse lapansi chaka chilichonse, ndipo akhala mdani wamkulu wa thanzi la anthu.Kuchuluka komanso kufa kwa matenda amtima kumawongolera njira ya mankhwala R & D ndi kupanga.Mankhwala amtima ndi cerebrovascular adapanga 4 mwa mankhwala 10 ogulitsidwa kwambiri padziko lonse lapansi mu 2005. Pali mitundu yambiri yamankhwala ovomerezeka aku China ochizira matenda amtima, koma palibe mitundu yopitilira itatu (Fuzheng Ningxin, onunkhira Wentong). , kulimbikitsa kuyendayenda kwa magazi ndi kuchotsa stasis ya magazi).Kuchokera kuzinthu zogulitsa pamsika wogulitsa, Vitexin ndi mankhwala ena olimbikitsa kuyendayenda kwa magazi ndi kuchotsa ma stasis a magazi ali ndi malonda abwino.Ndi amodzi mwa mankhwala omwe amakula mwachangu.Msika ukukula mwachangu, uli ndi kuthekera kwakukulu, msika wawukulu wamsika komanso malo ampikisano ambiri.
Vitexin ndi gawo lachilengedwe la mankhwala a anti-cancer ndi anti-chotupa.Diaz Wachilendo adanena kuti flavonoids yomwe inapezedwa kuchokera ku Vitex negundo, monga Vitexin, inasonyeza kwambiri cytotoxicity ku maselo a khansa ya anthu mu bioassay;Massateru et al.Anapeza kuti bauhinin inaletsa kukula kwa maselo a khansa ya m'mapapo (PC-12) ndi maselo a khansa ya m'matumbo (HCT116) mu mayeso a MTT.
Opanga ambiri opanga mbewu akupanga zotulutsa za Vitexin.Kuphatikiza pa kuchotsa kwa Vitexin, monga kuchotsa kwa Vitexin ndi hawthorn, onse akupanga Vitexin monga gawo lothandizira, ndipo zinthuzo zimagulitsidwanso kwa makasitomala omwe ali ndi Vitexin monga index.Mlozera wa Vitexin muzotulutsa za Vitex ndi hawthorn kwenikweni ndi pafupifupi 5%.
Ndikukhulupirira kuti mwawonanso malipoti ofanana ndi omwe amatsutsa khansa ndi khansa ya Hawthorn: kafukufuku waposachedwapa apeza kuti Hawthorn ili ndi mankhwala otchedwa Vitexin, omwe ali ndi zotsatira zotsutsana ndi khansa.Nitrosamine ndi aflatoxin zimatha kuyambitsa kapena kukulitsa khansa ya m'mimba.Kafukufuku woyeserera akuwonetsa kuti Tingafinye wa hawthorn sangalepheretse kaphatikizidwe ka nitrosamine, komanso kuletsa carcinogenic zotsatira za aflatoxin.Choncho, anthu omwe ali pachiopsezo chachikulu cha khansa ya m'mimba ayenera kudya hawthorn nthawi zambiri.Kwa odwala khansa, hawthorn ndi mpunga zitha kugwiritsidwanso ntchito kuphika phala limodzi ngati dyspepsia, zomwe sizingathandize kokha chimbudzi, komanso kuchita nawo gawo lothandizira polimbana ndi khansa.
Mankhwala a Vitexin ku Hawthorn ndi ochepa kwambiri kuposa a Vitexin, koma chifukwa ndi anthu ochepa omwe amadziwa komanso kumvetsa Vitexin kuti alemere, mphamvu yotsutsa khansa ndi khansa ya Vitexin yatsekedwa m'mapiri!