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OEM Factory for Cas No.63335-24-0 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian

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OEM Factory for Cas No.63335-24-0 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian Detail:

Essential Information

CAS No.: 524-30-1 [1]

EINECS No.: 208-355-5

Molecular Formula: c16h18o10

Molecular Weight: 370.3081

Molecular Structure: (Figure 1)

Properties: Light yellow acicular crystal or flake crystal.

Density: 1.634g/cm3

Boiling Point: 722.2 ° C at 760 mmHg

Flash Point: 267 ° C

Steam Pressure: 6.87e-22mmhg at 25 ° C

Bioactivity of Fraxin

Description: Fraxin can be isolated from Acer tegmentosum, F. ornus and a. hippocastanum. It is a glycoside of fraxine [1] and has antioxidant, anti-inflammatory and anti metastasis activities. Fraxin exhibits antioxidant activity by inhibiting cyclic adenylate phosphodiesterase [2].

Target: cyclo AMP phosphodiesterase enzyme [2]

In Vitro Study: Fraxin (100 μ M) It has no cytotoxicity to Hep G2 cells. Fraxin at non cytotoxic concentrations significantly reduced t-BHP induced ROS production in a dose-dependent manner [1]. Fraxin (0.5 mm) can scavenge free radicals at high concentration and has cytoprotective effect on H2O2 mediated oxidative stress [2].

In vivo study: Fraxin (50 mg / kg, PO) significantly blocked CCl4 induced elevation of ALT and AST. Fraxin (10 and 50 mg / kg, PO) significantly reduced GSSG levels (1.7 ± 0.3 and 1.5 ± 0.2 nm / g liver, respectively) compared with GSSG levels in the CCl4 treated group

Reference:. Fraxin (50 mg/kg, p.o.) significantly blocks the CCl4-induced elevation of ALT and AST. Fraxin (10 and 50 mg/kg, p.o.) significantly reduces the GSSG levels (1.7±0.3 and 1.5±0.2 nM/g liver, respectively) compared with the GSSG levels of the CCl4-treated group[1].

[2]. Whang WK, et al. Natural compounds,fraxin and chemicals structurally related to fraxin protect cells from oxidative stress. Exp Mol Med. 2005 Oct 31;37(5):436-46.


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OEM Factory for Cas No.63335-24-0 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1  –  Yongjian detail pictures

OEM Factory for Cas No.63335-24-0 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1  –  Yongjian detail pictures


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With advanced technologies and facilities, strict high quality regulate, reasonable price tag, excellent support and close co-operation with shoppers, we have been devoted to furnishing the best benefit for our buyers for OEM Factory for Cas No.63335-24-0 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian , The product will supply to all over the world, such as: Honduras, Oslo, Morocco, We have been making our products for more than 20 years . Mainly do wholesale , so we have the most competitive price , but highest quality. For the past years , we got very good feedbacks , not only because we provide good products , but also because of our good after-sale service . We are here waiting for you for your inquiry.
  • The goods are very perfect and the company sales manager is warmful, we will come to this company to purchase next time.
    5 Stars By Ryan from Malta - 2017.04.18 16:45
    The company can think what our think, the urgency of urgency to act in the interests of our position, can be said this is a responsible company, we had a happy cooperation!
    5 Stars By Maria from Washington - 2017.09.16 13:44
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