Orientin
Application of Orientin
Orientin is a naturally occurring bioactive flavonoid with a variety of biological characteristics, including anti-inflammatory, antioxidant, anti-tumor, heart protection and so on. Orientin is a promising neuroprotective agent, which is suitable for the treatment of neuropathic pain.
Bioactivity of Orientin
Description: orientin is a naturally occurring bioactive flavonoid with a variety of biological characteristics, including anti-inflammatory, antioxidant, anti-tumor, heart protection and so on. Orientin is a promising neuroprotective agent, which is suitable for the treatment of neuropathic pain.
Related Categories: research field > > cancer
Signal path > > other > > other
Research field > > neurological diseases
Reference: [1]. Dhakal H, et al. Inhibitory effects of orientin in mast cell-mediated allergic inflammation. Pharmacol Rep. 2020 Jan 24.
[2]. Guo D, et al. Orientin and neuropathic pain in rats with spinal nerve ligation. 61Int Immunopharmacol. 2018 May;58:72-79.
Physicochemical Properties of Orientin
Density: 1.8 ± 0.1 g / cm3
Boiling Point: 816.1 ± 65.0 ° C at 760 mmHg
Melting Point: 260-285 º C
Molecular Formula: C21H20O11
Molecular Weight: 448.377
Flash Point: 289.1 ± 27.8 ° C
Accurate Mass: 448.100555
PSA: 201.28000
LogP: 1.58
Appearance: yellow powder
Vapor Pressure: 0.0 ± 3.1 mmHg at 25 ° C
Refractive Index: 1.767
Water Solubility: 1 M
NaOH: soluble1mg / ml, clear, yellow orange
Digitalis safety information
Safety statement (Europe): 24 / 25
Transport code of dangerous goods: nonh for all modes of transportRTECS号:DJ3009300
Literature review of Orientin
Distinction of the C-glycosylflavone isomer pairs orientin/isoorientin and vitexin/isovitexin using HPLC-MS exact mass measurement and in-source CID.
Phytochem. Anal. 16(5) , 295-301, (2005)
HPLC-MS using collision induced dissociation (CID) has been utilised for the identification of the C-glycosylflavone isomer pairs orientin/isoorientin and vitexin/isovitexin. HPLC-CID/MS analyses prod..
Antihypertensive and cardioprotective effects of the Lagenaria siceraria fruit in NG-nitro-L-arginine methyl ester (L-NAME) induced hypertensive rats.
Pharm. Biol. 50(11) , 1428-35, (2012)
Lagenaria siceraria (Molina) Standl. (Cucurbitacae) (LS) has been reported to possess cardioprotective, antihyperlipidemic, and diuretic activities.To evaluate antihypertensive and cardioprotective ef...
Development and validation of an HPTLC method for simultaneous quantitation of isoorientin, isovitexin, orientin, and vitexin in bamboo-leaf flavonoids.
J. AOAC Int. 93(5) , 1376-83, (2010)
A simple HPTLC method has been developed for the simultaneous determination of isoorientin, isovitexin, orientin, and vitexin, both pure and in commercial samples of bamboo-leaf flavonoids. The flavon...
English Alias of Orientin
(1S)-1,5-Anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-D-glucitol
2-(3,4-Dihydroxyphényl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]-4H-chromén-4-one
Orientin 8-C-β-D-glucopyranoside
3',4',5,7-tetrahydroxyflavone-8-C-glucoside
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-4H-chromen-4-on
Luteolin-8-C-glucoside
3',4',5,7-tetrahydroxyflavone 8-glucoside
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-
D-Glucitol, 1,5-anhydro-1-C-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-8-yl]-, (1S)-
Orientin
lutexin
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]-4H-chromen-4-one
2-(3,4-Dihydroxyphenyl)-8-b-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
