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Personlized Products Cas No.61276-17-3 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian

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Personlized Products Cas No.61276-17-3 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian Detail:

Essential Information

CAS No.: 524-30-1 [1]

EINECS No.: 208-355-5

Molecular Formula: c16h18o10

Molecular Weight: 370.3081

Molecular Structure: (Figure 1)

Properties: Light yellow acicular crystal or flake crystal.

Density: 1.634g/cm3

Boiling Point: 722.2 ° C at 760 mmHg

Flash Point: 267 ° C

Steam Pressure: 6.87e-22mmhg at 25 ° C

Bioactivity of Fraxin

Description: Fraxin can be isolated from Acer tegmentosum, F. ornus and a. hippocastanum. It is a glycoside of fraxine [1] and has antioxidant, anti-inflammatory and anti metastasis activities. Fraxin exhibits antioxidant activity by inhibiting cyclic adenylate phosphodiesterase [2].

Target: cyclo AMP phosphodiesterase enzyme [2]

In Vitro Study: Fraxin (100 μ M) It has no cytotoxicity to Hep G2 cells. Fraxin at non cytotoxic concentrations significantly reduced t-BHP induced ROS production in a dose-dependent manner [1]. Fraxin (0.5 mm) can scavenge free radicals at high concentration and has cytoprotective effect on H2O2 mediated oxidative stress [2].

In vivo study: Fraxin (50 mg / kg, PO) significantly blocked CCl4 induced elevation of ALT and AST. Fraxin (10 and 50 mg / kg, PO) significantly reduced GSSG levels (1.7 ± 0.3 and 1.5 ± 0.2 nm / g liver, respectively) compared with GSSG levels in the CCl4 treated group

Reference:. Fraxin (50 mg/kg, p.o.) significantly blocks the CCl4-induced elevation of ALT and AST. Fraxin (10 and 50 mg/kg, p.o.) significantly reduces the GSSG levels (1.7±0.3 and 1.5±0.2 nM/g liver, respectively) compared with the GSSG levels of the CCl4-treated group[1].

[2]. Whang WK, et al. Natural compounds,fraxin and chemicals structurally related to fraxin protect cells from oxidative stress. Exp Mol Med. 2005 Oct 31;37(5):436-46.


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Personlized Products  Cas No.61276-17-3 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1  –  Yongjian detail pictures

Personlized Products  Cas No.61276-17-3 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1  –  Yongjian detail pictures


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Our goods are broadly recognized and reliable by users and can meet consistently switching financial and social demands of Personlized Products Cas No.61276-17-3 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian , The product will supply to all over the world, such as: Sevilla, Japan, Marseille, We care about every steps of our services, from factory selection, product development & design, price negotiation, inspection, shipping to aftermarket. We have implemented a strict and complete quality control system, which ensures that each product can meet quality requirements of customers. Besides, all of our products have been strictly inspected before shipment. Your Success, Our Glory: Our aim is to help customers realize their goals. We are making great efforts to achieve this win-win situation and sincerely welcome you to join us.
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    5 Stars By Christine from Provence - 2018.12.11 14:13
    The company keeps to the operation concept "scientific management, high quality and efficiency primacy, customer supreme", we have always maintained business cooperation. Work with you,we feel easy!
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