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Professional China Cas No.55466-04-1 - Ophiopogonin D Cas No.945619-74-9 – Yongjian

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Professional China Cas No.55466-04-1 - Ophiopogonin D Cas No.945619-74-9 – Yongjian Detail:

Ophiopogon Saponin D Name

English Name: (1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-6-deoxy-β-D-galactopyranoside

Bioactivity of Ophiopogon Japonicus Saponin D

Description: Ophiopogon D is a rare natural C29 steroidal glycoside isolated from the tuber of Ophiopogon japonicus. Ophiopogonin D is a CYP2J3 inducer that increases CYP2J2 / eets and PPAR in human umbilical vein endothelial cells (HUVECs) α The expression of Ang II significantly inhibited Ang II induced NF- κ B nuclear translocation, I κ B α Down regulation, intracellular Ca2 + overload and activation of proinflammatory cytokines. Ophiopogonin D has been used to treat inflammation and cardiovascular diseases for thousands of years.

Relevant Categories

Signaling pathway > > transmembrane transport > > calcium channel

Research field > > cardiovascular disease

Signaling pathway > > cell cycle / DNA damage > > PPAR

Research field > > inflammation / immunity

Target

PPARα

NF-κB

Ca2+

Reference Documents: [1]. Wang L , et al. Homo-aro-cholestane, furostane and spirostane saponins from the tubers of Ophiopogonjaponicus. Phytochemistry. 2017 Apr;136:125-132.

[2]. Huang X, et al. Ophiopogonin D and EETs ameliorate Ang II-induced inflammatory responses via activating PPARα in HUVECs. Biochem Biophys Res Commun. 2017 Aug 19;490(2):123-133.

English Alias of Ophiopogon saponin D

(1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-6-deoxy-β-D-galactopyranoside β-D-Galactopyranoside, (1β,3β,25R)-3-hydroxyspirost-5-en-1-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-xylopyranosyl-(1->3)]-6-deoxy-

(2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-5-hydroxy-2-(((4R,5′R,6R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-4-hydroxy-5′,6a,8a,9-tetramethyl-1,3,3′,4,4′,5,5′,6,6a,6b,6′,7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2′-pyran]-6-yl)oxy)-6-methyl-4-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol

Ophiopogonin D

Deacetylophiopogonin C


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Professional China  Cas No.55466-04-1 - Ophiopogonin D Cas No.945619-74-9 –  Yongjian detail pictures

Professional China  Cas No.55466-04-1 - Ophiopogonin D Cas No.945619-74-9 –  Yongjian detail pictures


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We believe that prolonged expression partnership is really a result of top of the range, value added support, rich encounter and personal contact for Professional China Cas No.55466-04-1 - Ophiopogonin D Cas No.945619-74-9 – Yongjian , The product will supply to all over the world, such as: Macedonia, UK, Nigeria, We welcome customers from all over the world come to discuss business. We supply high quality solutions, reasonable prices and good services. We hope to sincerely build business relationships with customers from at home and abroad, jointly striving for a resplendent tomorrow.
  • The factory technical staff not only have high level of technology, their English level is also very good, this is a great help to technology communication.
    5 Stars By Clementine from Egypt - 2017.02.14 13:19
    As a veteran of this industry, we can say that the company can be a leader in the industry, select them is right.
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