Ophiopogonin D Cas No.945619-74-9
Ophiopogon Saponin D Izina
Izina ry'icyongereza:. (1β, 3β, 25R) -3 -6-deoxy-β-D-galactopyranoside
Bioactivite ya Ophiopogon Japonicus Saponin D.
Ibisobanuro:Ophiopogon D ni gake ya C29 steroidal glycoside yitaruye ikirayi cya Ophiopogon japonicus.Ophiopogonin D ni inducer ya CYP2J3 yongerera CYP2J2 / eets na PPAR mu ngirangingo z'umuntu zifata ingirabuzimafatizo (HUVECs) α Imvugo ya Ang II yabujije cyane Ang II itera NF- κ B guhinduranya, I κ B α Hasi, Ca2 + kurenza urugero no gukora prinflammatory cytokine.Ophiopogonin D imaze imyaka ibihumbi ikoreshwa mu kuvura indwara n’indwara zifata umutima.
Ibyiciro bijyanye
Inzira yerekana ibimenyetso >> transport ya transembrane >> umuyoboro wa calcium
Urwego rwubushakashatsi >> Indwara yumutima
Inzira yerekana inzira >> ingirabuzimafatizo / kwangirika kwa ADN >> PPAR
Umwanya wubushakashatsi >> gutwika / ubudahangarwa
Intego
PPARα
NF-κB
Ca2 +
Inyandiko zerekana:[1].Wang L, n'abandi.Homo-aro-cholestane, furostane na spirostane saponine iva mubijumba bya Ophiopogonjaponicus.Phytochemie.2017 Mata; 136: 125-132.
[2].Huang X, n'abandi.Ophiopogonin D na EETs bizamura Ang II-iterwa no gutwika ibisubizo ukoresheje PPARα muri HUVECs.Biochem Biophys Res Commun.2017 Kanama 19; 490 (2): 123-133.
Icyongereza Alias cya Ophiopogon saponin D.
. (1β, 3β, 25R) -3 -6-deoxy-β-D-galactopyranoside β-D-Galactopyranoside, (1β, 3β, 25R) -3-hydroxyspirost-5-en-1-yl O-6-deoxy-α-L-mannopyranosyl- (1- > 2) -O- [β-D-xylopyranosyl- (1-> 3)] - 6-deoxy-
(2S, 3R, 4R, 5R, 6S) -2 - ((2R , 8bR, 9S, 10R, 11aS, 12aS, 12bS) -4-hydroxy-5 ', 6a, 8a, 9-tetramethyl-1,3,3', 4,4 ', 5,5', 6,6a, 6b, 6 ', 7,8,8a, 8b, 9,11a, 12,12a, 12b-icosahydrospiro [naphtho [2', 1 ': 4,5] indeno [2,1-b] furan-10,2 '-pyran] -6-yl) oxy) -6-methyl-4 - (((2S, 3R, 4S, 5R) -3,4,5-trihydroxytetrahydro-2H-pyran-2-yl) oxy) tetrahydro- 2H-pyran-3-yl) oxy) -6-methyltetrahydro-2H-pyran-3,4,5-triol
Ophiopogonin D.
Deacetylophiopogonin C.
