Synephrine
Gukoresha Synephrine
Synephrine (oxedrine) ikomoka ku bimera bya citrus α- Adrenergique na β- Adrenergic agonist bafite simpathomic and structure ihuye na ephedra na ephedrine alkaloide.
Izina rya Synephrine
Izina ry'icyongereza: synephrine
Igishinwa bita: deoxyepinephrine |simforine |DL deoxyepinephrine |1-p-hydroxyphenyl-2-methylaminoethanol |cinephrine |1 - (4-hydroxyphenyl) - 2 - (methylamino) Ethanol
Bioactivite ya Synephrine
Ibisobanuro: synephrine (oxedrine) ikomoka ku bimera bya citrusi α- Adrenergique na β- Adonergic agoniste bafite impuhwe n’imiterere bisa na ephedra na alkaloide ya ephedrine.
Ibyiciro bijyanye: α- adrenergic na β- adrenergique [1]
Mu bushakashatsi bwa Vivo: adrenaline (1mg / kg; gavage yo mu kanwa; imara iminsi 8; imbeba za PVL na BDL) yazamuye cyane imiterere ya hyperkinetic ya PVL na BDL.Imbeba za PVL na BDL zagabanutse cyane umuvuduko wumuvuduko wamaraso, ishami ryumuvuduko wamaraso wamaraso hamwe nindwara yumutima, mugihe kuvura adrenaline byiyongereye bivuze umuvuduko wamaraso hamwe na sisitemu yo mumitsi hamwe no kurwanya imiyoboro y'amaraso [2].Icyitegererezo cyinyamanswa: Imbeba zifite imiyoboro y'amaraso (PVL) cyangwa imiyoboro y'amazi (BDL) [2] ikinini: 1 mg / kg buri masaha 12: gavage yo mu kanwa;Ibisubizo kumunsi wa 8: Imbeba za PVL na BDL zaragabanutse cyane umuvuduko wumuvuduko wamaraso, ishami ryamaraso yamaraso hamwe numutima wumutima, kandi byongera umuvuduko ukabije wamaraso hamwe no kurwanya imitsi ya sisitemu.
Reba: 1] Thomas JE, n'abandi.STEMI mumusore wimyaka 24 nyuma yo gukoresha synephrine irimo ibiryo byuzuye: raporo y'urubanza no gusuzuma ibitabo.Tex Umutima Inst J. 2009;36 (6): 586-90.
[2].Huang YT, n'abandi.Ingaruka ya Hemodinamike yo kuvura synephrine muri portal hypertensive imbeba.Jpn J Pharmacol.2001 Gashyantare;85 (2): 183-8.
Ibintu bya fiziki ya Himiki ya Simephrine
Ubucucike: 1.2 ± 0.1 g / cm3
Ingingo yo guteka: 341.1 ± 27.0 ° C kuri 760 mmHg
Ingingo yo gushonga: 187 ° C (Ukuboza) (lit.)
Inzira ya molekulari: C9H13NO2
Uburemere bwa molekuline: 167.205
Ingingo yerekana: 163.4 ± 14.3 ° C.
Misa nyayo: 167.094635
PSA: 52.49000
LogP: -0.03
Kugaragara: kure yera kugirango ifu ya beige
Umuvuduko wamazi: 0.0 ± 0.8 mmHg kuri 25 ° C.
Ironderero: 1.572
Imiterere yo kubika: Iki gicuruzwa kigomba gufungwa no kubikwa.
Amakuru Yumutekano Ya Synflynn
Ikimenyetso: ghs07
Ijambo ry'ikimenyetso: kuburira
Amagambo ya Hazard: h315-h319-h335
Itangazo ryo kuburira: p261-p305 + P351 + P338
Ibikoresho byo kurinda umuntu ku giti cye: ubwoko bwa mask ivumbi N95 (US);Amaso;Gants
Kode ya Hazard (Uburayi): Xi: iritant;
Ibisobanuro (Europe): R36 / 37/38
Umutekano (Uburayi): s26-s36
Kode yo gutwara ibicuruzwa biteje akaga: nonh kuburyo bwose bwo gutwara
RTECS No.: Do7350000
Kode ya gasutamo: 2922199090
Gutegura Synephrine
Ibisubizo bya citrus aurantium L.
Imigenzo ya Synephrine
Kode ya gasutamo: 29225090
Incamake y'Abashinwa: 29225090 Izindi fenolike ya alcool, aminide acide amine hamwe nandi mavuta ya ogisijeni ya aminide igabanya umusoro ku nyongeragaciro: 17.0% Igipimo cy’imisoro: 13.0% Ibisabwa: ab.Igiciro cya MFN: 6.5% Igiciro rusange: 30.0%
Ibimenyekanisha: Izina ryibicuruzwa, ibiyigize, ibiyirimo, intego, chroma ya Ethanolamine n'umunyu wacyo bizamenyeshwa, kandi gupakira Ethanolamine n'umunyu wacyo.
Ibisabwa byo kugenzura: A. urupapuro rwerekana ibicuruzwa biva mu mahanga B. Ifishi yo gutumiza gasutamo ku bicuruzwa biva hanze
Kugenzura na Karantine: R. kugenzura isuku no kugenzura ibiryo bitumizwa mu mahanga S. kugenzura isuku no kugenzura ibiribwa byoherejwe hanze;
Incamake: 2922509090.andi amino-alcool-fenol, amino-acide-fenoline nandi amin-compound hamwe na ogisijeni ikora.TVA: 17.0%.Igipimo cyo kugabanyirizwa imisoro: 13.0%..Igiciro cya MFN: 6.5%.Igiciro rusange: 30.0%
Ubuvanganzo bwa Synephrine
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Icyongereza Alias Ya Synephrine
Synefrin
Simpatol
EINECS 202-300-9
4 - [(1R) -1-Hydroxy-2- (methylamino) ethyl] phenol
(-) - Oxedrine
Oxedrine
(-) - Sympatol
(R) -4- (1-hydroxy-2- (methylamino) ethyl) phenol
1- (4-Hydroxyphenyl) -2-methylaminoethanol
Synephrin
Ethaphene
Analeptin
Simpalon
(-) - Synephrine
Benzenemethanol, 4-hydroxy-α - [(methylamino) methyl] -, (αR) -
Synephrine
MFCD00002370
D-Synephrine
(-) - 4-hydroxy-α - [(methylamino) methyl] benzenemethanol
Sympathol
Pentrin
(-) - p-hydroxy-α - [(methylamino) methyl] inzoga ya benzyl
