Paeoniflorin CAS Numera 23180-57-6
Fa'amatalaga Taua
E lauiloa foi o le paeoniflorin, o se pinane monoterpene bitter glycoside e vavae ese mai peony mumu ma peony paepae.O se pauta amorphous hygroscopic.E i ai i aʻa o Paeonia, peony, lanu viole peony ma isi laau o Ranunculaceae.O le oona o lenei tioata e matua maualalo lava.
[igoa kemisi]5beta-[(Benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd] pentalen-1alpha(2H)-yl-beta-D-glucopyranoside
[fua mole mole]C23H28O11
【CASleai】23180-57-6
Mama: sili atu i le 98%, auala e iloa ai: HPLC.
[puna]o aʻa o Paeonia albiflora pall, P. suffrsticosa Andr, P. delarayi Franch, o se laau o Ranunculaceae, o le mea o loʻo i totonu o le radix paeoniae Rubr e sili ona maualuga.
[Fa'amatalaga]10%，20%，30%，50%，90%，98%
[AgalueImea'ai ] Aofa'i glucosides o Paeonia (TGP) o le igoa lautele o paeoniflorin, hydroxy paeoniflorin, paeoniflorin, albiflorin ma benzoyl paeoniflorin, lea e taʻua TGP mo puupuu.
Fa'aletino ma kemisi
O le hygroscopic amorphous Tan pa'u (90% e ese le pa'epa'e pa'epa'e) [α] 16D-12.8. (C = 4.6, methanol), tetraacetate o le lanu tioata acicular, mea liusuavai: 196 ℃.Paeoniflorin e mautu i le siosiomaga acidic (pH 2 ~ 6) ma le mautu i alkaline siosiomaga.
Filifiliga o mea
E masani lava, o le auala 1 ma le auala 2 e mafai foi ona faʻaaogaina mo le suʻeina.Metotia 1 e sili ona faʻaaogaina mo le gaosiga o mea e maualuga, lea e mafai ona fesoasoani i le faʻagasologa o tagata faigaluega e faʻamasinoina le mama o oloa.O le mea fa'asino e faigofie ona pala pe a uma ona fa'amavae.
1. Na fuafuaina e le chromatography vai maualuga (Faaopoopoga VI d).O tulaga chromatographic ma le talafeagai o le faiga na tofotofoina i le Octadecyl silane bonded silica gel e fai ma faatumu;Acetonitrile-0.1% phosphoric acid solution (14:86) na faʻaaogaina e avea ma vaega feaveaʻi;Ole umi ole su'esu'eina ole 230nm.Ole numera o ipu faʻataʻitaʻiga e fuafua e tusa ai ma le paeoniflorin peak e le tatau ona itiiti ifo i le 2000. Sauniuniga o faʻamatalaga faʻamatalaga: fuaina saʻo se aofaiga talafeagai o le paeoniflorin reference solution ma faʻaopopo le methanol e saunia ai le 60% paeoniflorin i le 1ml μG solution.
2.Ia faʻaleleia le auala faʻamoemoe o paeoniflorin i Radix Paeoniae Alba.Metotia: o metotia i le Chinese Pharmacopoeia ma auala faʻaleleia na faʻatusatusa.O le vaega feaveai o le vai methanol (30:70) ma o le umi o le galu e iloa ai o le 230nm.taunuuga;O le laina laina o lenei metotia e lelei (r = 0.9995).Ole averesi ole toe faʻaleleia ole 101.518% ma le RSD ole 1.682%.Faʻaiʻuga: o le faʻaleleia atili o le auala e faigofie ma saʻo, lea e mafai ona faʻaitiitia ai le oona o solvents organic i tagata soifua ma le faʻaleagaina o le siosiomaga, ma tuʻuina atu se faʻavae faʻavae mo le fuafuaina o paeoniflorin i le faʻatinoga.
Metotia Filifiliga
Fuafuaga o paeoniflorin e HPLC
Avanoa o le talosaga:O lenei metotia e faʻaogaina ai le HPLC e fuafua ai mea o loʻo i totonu o le paeoniflorin i totonu o fualaau o Guizhi Fuling.
O le auala e talafeagai mo Guizhi Fuling pill.
Metotia mataupu faavae:tuʻu le faʻataʻitaʻiga faʻataʻitaʻiga i totonu o se fagu conical, faʻaopoopo se aofaiga talafeagai o le ethanol faʻafefe mo le faʻaaogaina o le ultrasonic, faʻamafanafana, lulu lelei, faamama, o le filtrate e ulufale i le chromatograph vai maualuga mo le vavaeeseina o le chromatographic, faʻaaoga le ultraviolet absorption detector e iloa ai le le aoga o le absorption o paeoniflorin i le galu o le 230nm, ma fuafua lona anotusi.
