Esculin;Aesculin;Esculoside;Bicolorin;Escosyl
Kushandiswa kweEsculin
Bioflavonoids, antioxidant, inosimudzira zvirimo muvhitamini C.
Chiito cheEsculin
1. Anti kuzvimba uye analgesia: makonzo akaiswa intraperitoneally ne 10mg / kg.Carrageenan induced, dextrose induced, serotonin induced uye histamine induced "arthritis" yakanga ine inhibitory effects, uye inhibitory intensity yaiva 35,28,20,8% zvichiteerana Inoshumwawo kuti ine inhibitory effect pa formaldehyde induced arthritis, asi mhedzisiro yacho. isina simba kupfuura iyo carrageenan induced arthritis;Iyo inhibition ye dextran arthritis haisi pachena Inogona kudzivisa kuumbwa kwegranuloma mumakonzo (cotton ball method), erythema reaction inokonzerwa ne ultraviolet radiation pamusana penguruve, uye kuwedzera kwe capillary permeability inokonzerwa ne histamine Iine kushaya simba kweanalgesic effect. .
2. Mhedzisiro pahuwandu hweweti uye uric acid excretion: nzira dzakasiyana-siyana dzekutonga dzinogona kuwedzera uric acid excretion mumakonzo netsuro, uye haina diuretic effect pamakonzo akajairika, asi ine yakakosha diuretic effect pamakonzo.
3.Zvimwe: antibacterial, anticoagulant uye inhibiting aldose reductase mune rat lens.
Zita reEsculin
Chirungu Zita :esculin
Zita rechiChinese:Heptachlor hemihydrate |heptachlor hemihydrate |6-( β- D-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-one |aescin |bhiza chestnut bark glycoside |chestnut bark glycoside Seven shizha mweya Aescin |Qiyeling |chestnut bark glycoside |aescin |6 - (beta-d-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-one
Bioactivity yeEsculin
Tsanangudzo: esculin inonzi fluorescent coumarin glucoside, inova chikamu chinoshanda chegrey bark.Esculin inovandudza kukanganisa kwekuziva mukuedza kwechirwere cheshuga nephropathy (DN) kuburikidza neMAPK nzira yekusaina, uye inopa antioxidant kusagadzikana uye anti-kuzvimba mhedzisiro.
Related Categories: research field > > cancer
Chinangwa: p38 MAPK
Reference:
[1].Knox K, nevamwe.Iyo Coumarin Glucoside, Esculin, Inoratidza Kukurumidza Kuchinja muPhloem-Transport Velocity mukupindura kune Environmental Cues.Plant Physiol.2018 Oct;178(2):795-807.
[2].Rwiyo Y, nevamwe.Esculin inovandudza kukanganisa kwekuziva mukuedza kwechirwere cheshuga nephropathy uye inokonzera anti-oxidative kusagadzikana uye anti-inflammatory effects kuburikidza neMAPK nzira.Mol Med Rep. 2018 May;17(5):7395-7402.
Physicochemical Properties yeEsculin
Density: 1.7 ± 0.1 g / cm3
Boiling Point: 697.7 ± 55.0 ° C pa 760 mmHg
Kunyungudika: 203 ° C
Molecular Formula: c15h16o9
Molecular uremu: 358.297
Flash Point: 262.8 ± 25.0 ° C
Hukuru chaihwo: 358.089996
PSA:358.089996
LogP:-1.52
Kuonekwa: cream powder
Steam Pressure: 0.0 ± 2.3 mmHg pa25 ° C
Refractive Index: 1.689
Storage Conditions
1 Chengeta muimba yekuchengetera inotonhorera, yakaoma uye ine mhepo yakanaka.Ramba kure nezvinobatidza nekupisa.Dzivirira kubva kuzuva rakananga.Package sealing.Ichachengetwa zvakasiyana kubva kune acids uye makemikari anodyiwa, uye kusanganiswa kwekuchengetedza hakubvumirwi.Nzvimbo yekuchengetera ichave yakashongedzerwa nezvinhu zvakakodzera kuti ive nekudonha.
2. Argon yakazadza chengetedzo yakavharwa
Kugadzikana: shandisa uye chengetedza zvinoenderana nezvakatemwa pasina kuora uye kudzivirira kusangana nemaokisi
Mvura Solubility: modhi inonyungudika
Molecular Structure
1. Molar refractive index: 77.35
2. Molar volume (cm3 / mol): 202.6
3. Isotonic chaiyo vhoriyamu (90.2k): 628.5
4. Kushungurudzika kwepamusoro (dyne / cm): 92.6
5. Polarizability (10-24cm3): 30.66
Esculin Safety Information
Kodhi yengozi (Europe): F, C, Xi
Chirevo cheNjodzi (Europe): R11
Chirevo Chekuchengetedza (Europe): s26-s36 / 37 / 39-s45-s24 / 25
Yekutakura Kodhi yezvinhu zvine njodzi: UN 2924 3 / PG 2
Wgk Germany: 3
RTECS Nhamba: dj3085000
Customs Code: 2942000000
Esculin Customs
Customs Code:2942000000
Chirungu Alias of Esculin
Crataegin
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside
EINECS 208-517-5
vitaminic2
Enallachrome
Esculetin 6-β-D-glucoside
POLYDROM
Bicolorin
Esculetin 6-O-glucoside
Polychrom
7-Hydroxy-2-oxo-2H-chromen-6-yl-β-D-glucopyranoside
BICOLOIN
7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate
Esculin
7-Hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2H-chromen- 2-imwe
6-(β-D-Glucopyranosyloxy) -7-hydroxy-2H-1-benzopyran-2-one
Esculetin 6-bD-glucoside
2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy) -7-hydroxy-
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1:1)
Aesculin
MFCD00006879
Esculetin-6-O-glucoside
2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy) -7-hydroxy-, hydrate (1:1)
Escosyl
