Methylophiopogonanone B
Kushandiswa kweMethylophiopogonanone B
Methylophiopogonone B, yakakwira isodihydroflavone, yakatorwa kubva pamudzi weOphiopogon japonicus, ine yakakwira antioxidant kugona.Methylophiopogonone B inowedzera GTP Rho uye inoita kuburikidza neRho yekusaina nzira.Methylophiopogonone B induces cell morphological change, kusanganisira dendritic contraction uye stress fiber kuumbwa, kuburikidza ne actin cytoskeleton reorganization.
Zita reMethylophiopogonanone B
Chirungu Zita:
(3R) -5,7-Dihydroxy-3-(4-methoxybenzyl)-6,8-dimethyl-2,3-dihydro-4 H-chromen-4-imwe
Biological chiitiko cheMethylophiopogonanone B
Tsanangudzo: methylophiopogonone B, yakakwira isodihydroflavone, yakatorwa kubva pamudzi weOphiopogon japonicus, ine yakakwirira antioxidant kugona.Methylophiopogonone B inowedzera GTP Rho uye inoita kuburikidza neRho yekusaina nzira.Methylophiopogonone B induces cell morphological change, kusanganisira dendritic contraction uye stress fiber kuumbwa, kuburikidza ne actin cytoskeleton reorganization.
Related Categories: research field > > zvimwe
chiratidzo nzira>> G protein yakasanganiswa receptor /
G protein > > RAS
Zvinyorwa: [1] Wang Y, et al.Homoisoflavonoids uye Antioxidant
Chiitiko cheOphiopogon japonicus Root.
Ito Y, nevamwe.A novel agent, methylophiopogonanone B,
inokurudzira Rho activation uye tubulin depolymerization.Mol Cell Biochem.2007 Mar;297(1-2):121-9.Epub 2006 Gumiguru 7.
Physicochemical properties yeMethylophiopogonanone B
Density: 1.285
Boiling Point: 554.5 ± 49.0 ° C pa 760 mmHg
Molecular Formula: C19H20O5
Molecular uremu: 328.359
Inopenya nzvimbo: 201.5 ± 23.3 ° C
Hukuru chaihwo: 328.131073
PSA: 75.99000
Nhamba: 5.22
Kutsiga kwemhepo: 0.0 ± 1.6 mmHg pa25 ° C
Refractive index: 1.617
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Yakagadzirirwa Sevhisi Yemakemikari Reference Zvishandiso Zvechinyakare Chinese Mushonga
Jiangsu Yongjian Pharmaceutical Technology Co., Ltd. inonyanya kuita tsvakiridzo yezvinhu zvinoshanda zvemishonga yechivanhu yechiChinese kweanopfuura makore gumi.Kusvika pari zvino, kambani iyi yakaita tsvakiridzo yakadzama pamhando dzinopfuura zana dzemishonga inowanzo shandiswa yechinyakare yeChinese, uye yakabudisa zviuru zvemakemikari.
Iyo kambani ine vepamusoro R & D vashandi uye yakakwana yekuyedza uye yekuongorora michina muindastiri, uye yakashanda mazana emasaenzi ekutsvagisa masangano.Inogona kukurumidza uye inobudirira kusangana nezvinodiwa nevatengi
Kupatsanura Kusachena Kwezvinodhaka, Gadziriro uye Chimiro Chekusimbisa Sevhisi
Zvisina kuchena muzvinodhaka zvakanyatsoenderana nehutano, kuchengeteka uye kugadzikana kwezvinodhaka.Kugadzirira uye kusimbiswa kwechimiro chekusachena mumishonga kunogona kutibatsira kunzwisisa nzira dzetsvina uye kupa hwaro hwekuvandudzwa kwemaitiro ekugadzira.Nokudaro, kugadzirira uye kuparadzaniswa kwetsvina kwakakosha zvikuru pakutsvakurudza kwezvinodhaka uye kubudirira.
Zvisinei, zviri mukati metsvina mumushonga zvakaderera, kunobva kwakafara, uye chimiro chacho chinonyanya kufanana nechikamu chikuru.Ndeipi tekinoroji inogona kushandiswa kuparadzanisa uye kuchenesa zvese zvinosvibisa mumushonga mumwe nemumwe uye nekukurumidza?Ndeapi maitiro uye nzira dzinoshandiswa kusimbisa chimiro chetsvina iyi?Uku ndiko kuoma uye dambudziko rakatarisana nezvikamu zvakawanda zvemishonga, kunyanya makambani emishonga emushonga wezvirimwa uye weChinese patent mushonga.
Zvichienderana nezvido zvakadaro, kambani yakatanga kupatsanurwa kwemishonga yekusachena uye masevhisi ekuchenesa.Kuvimba nenyukireya magineti resonance, mass spectrometry uye zvimwe zvishandiso uye matekinoroji, kambani inogona kukurumidza kuona chimiro cheakaparadzaniswa akapatsanurwa, kuitira kuti isangane nezvinodiwa nevatengi.
SPF Mhuka Kuedza
Nzvimbo yekuvaka yenzvimbo yekuedza mhuka ndeye 1500 square metres, inosanganisira mazana mana emamita enzvimbo yeSPF level uye zana emamita eP2 level cell laboratory.Inotungamirwa nevesainzi veChina Pharmaceutical University, inoumba yepakati tekinoroji timu ine vakati wandei vanodzoka.Ipa mhando dzemhando dzemhuka dzemhando yepamusoro, dhizaini yekuyedza, mapurojekiti ese uye mamwe masevhisi ekutsvagisa kwesainzi yebiomedical, kudzidzisa nekusimudzira maindasitiri.
Chikamu cheBhizinesi
1. Kudyisa mhuka duku
2. Kuenzanisa kwechirwere chemhuka
3. College project outsourcing
4. Pharmacodynamic evaluation in vivo
5. Pharmacokinetic evaluation
6. Tumor cell experimental service
Masimba Edu
1. Tarisa pakuedza chaiko
2. Kunyatsogadzirisa maitiro
3. Nyatsosaina chibvumirano chekuchengeta zvakavanzika
4. Murabhoritari wega pasina pakati zvinongedzo
5. Iyo nyanzvi yehunyanzvi timu inovimbisa yemhando yekuyedza
SPF yekuyedza nharaunda, yakanyatso kupihwa munhu kudya, chaiyo-nguva yekutevera yekuyedza kufambira mberi
