Esculin;Aesculin;Esculoside;Bicolorin;Escosyl
Codsiga Esculin
Bioflavonoids, antioxidant, waxay kor u qaadaan maadada fitamiin C.
Falka Esculin
1. Kahortagga caabuqa iyo xanuunka xanuunka: jiirka ayaa lagu duray intraperitoneal 10mg/kg.Carrageenan induced, dextrose induced, Serotonin induced iyo histamine induced "arthritis" ayaa saameyn ku yeeshay inhibitory, iyo xoojinta inhibitory waxay ahaayeen 35,28,20,8% siday u kala horreeyaan. oo ka daciifsan kii carrageenan ee arthritis-ka;Xakamaynta dextran arthritis-ku maaha mid cad Waxay joojin kartaa samaynta granuloma ee jiirka (habka kubbadda suufka), falcelinta erythema ee ay keento shucaaca ultraviolet ee dhabarka doofaarka guinea, iyo korodhka qulqulka xididada ee uu keeno histamine Waxay leedahay saameyn xanuunka daciifka ah. .
2. Saamaynta mugga kaadida iyo qashin-saarka uric acid: dariiqyada maamulka ee kala duwan waxay kor u qaadi karaan qashin-saarka uric acid ee jiirka iyo bakaylaha, wax saameyn ah kuma laha jiirka caadiga ah, laakiin waxay saameyn weyn ku leeyihiin jiirka.
3.Qaar kale: bakteeriyada, xinjirowga lidka ku ah iyo ka hortagga aldose reductase ee lenska jiirka.
Magaca Esculin
Magaca Ingiriisiga :esculin
Magaca Shiinaha: Heptachlor hemihydrate |heptachlor hemihydrate |6-（ β- D-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-hal |aescin |jilif xabadka fardaha glycoside |jilif chestnut glycoside Toddoba caleen ruux Aescin |Qiyeling |jilif chestnut glycoside |aescin |6 - (beta-d-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-hal
Bioactivity ee Esculin
Sharaxaad: esculin waa coumarin glucoside fluorescent, kaas oo ah qayb wax ku ool ah oo ka mid ah jilif cawl.Esculin waxay wanaajisaa garaadka daciifka ah ee nephropathy sonkorowga tijaabada ah (DN) iyada oo loo marayo dariiqa calaamadaynta MAPK, oo waxay keentaa diiqada antioxidant iyo saamaynta anti-bararka.
Qaybaha la xidhiidha: goobta cilmi-baarista > > kansarka
Bartilmaameedka: p38 MAPK
Tixraac:
[1]Knox K, iyo al.The Coumarin Glucoside, Esculin, waxay daaha ka qaadaysaa isbeddelada degdega ah ee xawaaraha gaadiidka Phloem-ka ee ka jawaabaya Tilmaamaha Deegaanka.Plant Physiol.2018 Oct;178 (2): 795-807.
[2].Heesta Y, iyo al.Esculin waxay hagaajisaa garashada daciifnimada nephropathy ee sonkorowga ee tijaabada ah waxayna kicisaa cadaadiska ka-hortagga oksaydhka iyo saamaynta ka-hortagga bararka iyada oo loo marayo dariiqa MAPK.Mol Med Rep. 2018 May;17 (5): 7395-7402.
Sifooyinka Physicochemical ee Esculin
Cufnaanta: 1.7 ± 0.1 g / cm3
Barta karkarinta: 697.7 ± 55.0 ° C at 760 mmHg
Meesha dhalaalaysa: 203 ° C
Qaacidada molecular: c15h16o9
Miisaanka Molecular: 358.297
Barta Tooshka ah: 262.8 ± 25.0 ° C
Tirada saxda ah: 358.089996
PSA:358.089996
LogP:-1.52
Muuqaalka: budada kareemka
Cadaadiska Uumiga: 0.0 ± 2.3 mmHg at 25 ° C
Tusmada dib-u-celinta: 1.689
Xaaladaha Kaydinta
1 Ku kaydi bakhaar qabow, qalalan oo hawo fiican leh.Ka fogow dabka iyo meelaha kulaylka.Ka ilaali iftiinka qorraxda tooska ah.Xiritaanka xirmada.Waa in si gooni ah loo kaydiyaa aashitada iyo kiimikooyinka la cuni karo, waana in aan la ogolaan kaydinta isku dhafan.Aagga kaydinta waa in lagu qalabeeyaa agab ku habboon oo ay ku jiraan daadinta.
2. Argon buuxiyey bakhaar daboolan
Xasilooni: u isticmaal oo kaydi si waafaqsan qeexitaannada iyada oo aan la dumin iskana ilaali xidhiidhka oksaydhka
Biyo Solubility: model milmaya
Qaab-dhismeedka Molecular
1. Tilmaanta dib u soo celinta Molar: 77.35
2. Mugga molar (cm3 / mol): 202.6
3. Isotonic mugga gaarka ah (90.2k): 628.5
4. Dusha sare (dyne / cm): 92.6
5. Polarizability (10-24cm3): 30.66
Macluumaadka Badbaadada Esculin
Koodhka halista (Yurub): F, C, Xi
Bayaanka Khatarta (Yurub): R11
Bayaanka Badbaadada (Yurub): s26-s36 / 37 / 39-s45-s24 / 25
Xeerka Gaadiidka ee alaabta khatarta ah: UN 2924 3 / PG 2
Wgk Germany: 3
RTECS No.: dj3085000
Xeerka Kastamka: 2942000000
Kastamka Esculin
Xeerka Kastamka:2942000000
Magaca Ingiriisiga ee Esculin
Crataegin
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside
EINECS 208-517-5
vitaminc2
Enallachrome
Esculetin 6-β-D-glucoside
POLYDROM
Bicolorin
Esculetin 6-O-glucoside
Polychrome
7-Hydroxy-2-oxo-2H-chromen-6-yl-β-D-glucopyranoside
BICOLOIN
7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate
Esculin
7-Hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2H-chromen- 2-hal
6- (β-D-Glucopyranosyloxy) -7-hydroxy-2H-1-benzopyran-2-hal
Esculetin 6-bD-glucoside
2H-1-Benzopyran-2-kow, 6- (β-D-glucopyranosyloxy) -7-hydroxy-
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1:1)
Aesculin
MFCD00006879
Esculetin-6-O-glucoside
2H-1-Benzopyran-2-kow, 6- (β-D-glucopyranosyloxy) -7-hydroxy-, hydrate (1: 1)
Escosyl
