Formononetin;7-Hydroxy-4'-Methoxyisoflavone
Codsiga Formononetin
Formononetin (formononetil; dhadhan), oo laga soo saaray dhir cas, waxay joojin kartaa kororka unugyada DU-145 / PC-3 qaab ku-tiirsanaan ah.
Magaca Formononetin
Magaca Shiinaha: formononetin
Magaca Shiinaha: 7-hydroxy-3 - (4-methoxyphenyl) chromone |shengyuanchanning B |anthocyanin |anthocyanin |anthocyanin |7-hydroxy-4-methoxyisobenzone |7-hydroxy-4 '- methoxyisoflavone |7-hydroxy-4' - methoxyisoflavone
Bioactivity ee Formononetin
Sharaxaad: formononetin (formononetil; dhadhan) ayaa laga soosaaray xabo casaan ah waxayna joojin kartaa faafitaanka unugyada DU-145 / PC-3 qaab ku tiirsan qiyaasta.
Qaybaha la xidhiidha: Alaabta Dabiiciga ah >> flavonoids
Goobta cilmi-baarista > > kansarka
Tixraac: [1].Liu XJ, iyo al.Kor u qaadida RASD1 iyo apoptosis ee DU-145 unugyada kansarka qanjirka 'prostate' ee bini'aadamka oo ay keentay formononetin in vitro.Asian Pac J Cancer Prev.2014;15 (6):2835-9.
[2].Zhang X, iyo al.Formononetin waxay keentaa apoptosis ee unugyada kansarka qanjirka 'prostate' ee PC-3 iyada oo kor u qaadeysa saamiga Bax/Bcl-2 iyo nidaaminta dariiqa p38/Akt.Nutr Cancer.2014;66 (4): 656-61.
[3]Chen J, iyo al.Formononetin waxay keentaa xidhitaanka wareegga unugyada unugyada kansarka naasaha bini'aadamka iyada oo loo marayo IGF1/PI3K/Akt dariiqyada in vitro iyo in vivo.Horm Metab Res.2011 Seb;43 (10):681-6.
Sifooyinka Kiimikaad ee Formononetin
Cufnaanta: 1.3 ± 0.1 g / cm3
Barta karkarinta: 479.4 ± 45.0 ° C at 760 mmHg
Meesha dhalaalaysa: 256-260 ° C
Qaacidada molecular: C16H12O4
Miisaanka Molecular: 268.264
Barta Tooshka ah: 183.4 ± 22.2 ° C
Tirada saxda ah: 268.073547
PSA:59.67000
Muuqaal: off budo cad
Cadaadiska Uumiga: 0.0 ± 1.2 mmHg at 25 ° C
Tusmada dib-u-celinta: 1.641
Xaaladaha Kaydinta: waa la xidhay oo lagu kaydiyaa meel hawo leh oo qallalan si looga fogaado inay taabto oksaydhyada kale.
Xasilooni: u isticmaal oo kaydi si waafaqsan qeexitaannada iyada oo aan la dumin iskana ilaali xidhiidhka oksaydhka
Sunta iyo Ecology ee Formononetin
Xogta deegaanka ee Formononetin
Maadadani waxay waxyeelo u geysan kartaa deegaanka, markaa waa in fiiro gaar ah loo yeesho jirka biyaha.
Macluumaadka badbaadada Formononetin
Astaanta:
Calaamadaha ereyga: digniin
Warbixinta Khatarta: h315-h319-h335
Qoraal Digniin ah: p280-p305 + P351 + p338-p337 + P313
Qalabka Ilaalinta Shakhsiyeed: Maaskarada Boodhka Nooca N95 (US);indho-shareer;Gacan-gashiyada
Code Hazard (Yurub): Xi: iritant
Bayaanka Khatarta (Yurub): R36 / 37/38
Bayaanka Badbaadada (Yurub): S37 / 39-s26-s36
Xeerka gaadiidka ee alaabta khatarta ah: noh ee dhammaan noocyada gaadiidka
Xeerka Kastamka: 2932990099
Kastamka Formononetin
Xeerka Kastamka: 2932990099
Dulmarka Shiinaha: 2932990099 Xeryahooda heterocyclic kale oo ay ku jiraan heteroatoms oxygen heteroatoms oo kaliya heerka VAT: 17.0% Heerka dhimista canshuurta: 13.0% Shuruudaha sharciyeynta: midna tacriif MFN: 6.5% Qiimaha guud: 20.0%
Qodobbada caddaynta: 2932990099 Iskudhisyada kale ee heterocyclic oo ay ku jiraan heteroatoms oxygen heteroatoms oo keliya heerka VAT: 17.0% Heerka dhimista canshuurta: 13.0% Shuruudaha sharciyeynta: midna tacriif MFN: 6.5% Qiimaha guud: 20.0%
Soo koobid:2932999099.xeryahooda heterocyclic kale oo leh oksijiin hetero-atom(yada) kaliya.VAT: 17.0%.Heerka dhimista canshuurta: 13.0%..Qiimaha MFN:6.5%.Qiimaha guud: 20.0%
Formononetin Literature
Flavonoids-ka udub dhexaad u ah horumarinta wakiilada cusub ee anti-angiogenic: Baaritaan tijaabo ah iyo xisaabin.
ArchBiochemBiophys577-578, 35-48, (2015)
Xidhiidhka ka dhexeeya kala duwanaanshaha qaab dhismeedka iyo hawlaha noolaha ee flavonoids ayaa weli ah hadal muhiim ah oo ka mid ah cilmi-baarista guud ee flavonoid.Daraasadda hadda jirta anti-angiogenic, cyt ...
Diyaarinta iyo qiimaynta silica dareeraha tricationic ionic ee dusha ku xidhan sida wejiyada taagan ee chromatography dareeraha waxqabadka sare leh.
J. Chromatogr.A. 1396, 62-71, (2015)
Laba dareere oo tricationic ionic ah ayaa la diyaariyey ka dibna lagu xidhay dusha sare ee taageeraya agabka silica iyada oo loo marayo "thiol-ene" riix kimistari oo ah weji cusub oo taagan oo loogu talagalay dareeraha waxqabadka sare leh.
Sodium Hydroxide waxa ay wanaajisaa soo saarista iyo falanqaynta Proanthocyanidins ee Ensiled Sainfoin (Onobrychis viciifolia).
J. Agric.Cuntada Chem.63, 9471-9, (2015)
Macluumaad yar ayaa ka jira saamaynta ensiling ee tannins-cufan ama proanthocyanidins.Baaritaanka acetone-butanol-HCl wuxuu ku habboon yahay cabbiraadda maaddooyinka proanthocyanidin ee tiro badan oo sam...
Magaca Ingiriisiga ee Formononetin
4H-1-Benzopyran-4-kow, 7-hydroxy-3- (4-methoxyphenyl)
7-hydroxy-4'-methoxy-Isoflavone (8CI)
8-Hydroxy-3- (4-methoxyphenyl) -4H-chromen-4-hal
Formononetol
4'-O-methyl-daidzein
4H-1-Benzopyran-4-kow, 7-hydroxy-3- (4-methoxyphenyl)
BIOCHANIN B
ForMonetin
BIOCHANIN A
Flavosil
7-Hydroxy-4'-methoxyisoflavone
Neochanin
Myconate
MFCD00016948
BiocaninB
FORMONETIN
8-Hydroxy-3- (4-methoxyphenyl) -4H-1-benzopyran-4-hal
EINECS 207-623-9
Formononetin
7-Hydroxy-3- (4-methoxyphenyl) chromone
loogu talagalay Monoetin