methyl rosmarinat
Codsiga Methyl Rosmarinate
Methyl rosmarinate waa xakameyn aan tartan lahayn tyrosinase ka go'doonsan Rabdosia serra.Qiimaha IC50 ee tyrosinase likaha waa 0.28 mm, sidoo kale waxay joojin kartaa a-glucosidase [1].
Magaca Methyl Rosmarinate
Magaca Shiinaha: Methyl rosmarinate
Waxqabadka Nafleyda ee Methyl Rosmarinate
Sharaxaad:
Methyl rosmarinate waa xakameyn aan tartan lahayn tyrosinase ka go'doonsan Rabdosia serra.Qiimaha IC50 ee tyrosinase likaha waa 0.28 mm, sidoo kale waxay joojin kartaa a-glucosidase [1]
Qaybaha la xidhiidha: goobta cilmi-baarista > > kale
dariiqa calaamadaynta > > dheef-shiid kiimikaadka enzyme / protease
>> tyrosinase
Bartilmaameedka: IC50: 0.28 mM (tyrosinase boqoshaada), a -glucosidase[1]
Tixraac:[1].Lin L, iyo al.Qiimaynta isbarbardhigga ee rosmarinic acid, methyl rosmarinate iyo pedalitin oo ka go'doonsan Rabdosia serra (MAXIM.) HARA sida horjoogayaasha tyrosinase iyo α-glucosidase.Cuntada Chem.2011 Dec 1;129(3):884-9.
Sifooyinka Kiimikaad ee Methyl Rosmarinate
Cufnaanta: 1.5 ± 0.1 g / cm3
Barta karkarinta: 655.4 ± 55.0 ° C at 760 mmHg
Qaacidada molecular: c19h18o8
Miisaanka Molecular: 374.341
Barta Tooshka ah: 236.5 ± 25.0 ° C
Tirada saxda ah: 374.100159
PSA:133.52000
LogP:2.12
Cadaadiska Uumiga: 0.0 ± 2.0 mmHg at 25 ° C
Tusmada dib-u-celinta: 1.668
Magaca Ingiriisida ee Guryaha Methyl Rosmarinate
(2R) -3- (3,4-dihydroxyphenyl) -1-methoxy-1-oxopropan-2-yl (2E) -3- (3,4-dihydroxyphenyl) prop-2-enoate
(2R) -3- (3,4-Dihydroxyphenyl) -1-methoxy-1-oxo-2-propanyl (2E) -3- (3,4-dihydroxyphenyl) acrylate
Benzenepropanoic acid, α-[[(2E) -3- (3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl] oxy]-3,4-dihydroxy-, methyl ester, (αR)
Adeegga Yongjian
Adeegga Habboon ee Qalabka Tixraaca Kiimikada ee Daawada Dhaqanka ee Shiinaha
Jiangsu Yongjian Pharmaceutical Technology Co., Ltd. ayaa inta badan ku hawlan cilmi-baarista aasaasiga ah ee walxaha firfircoon ee daawada dhaqameed ee Shiinaha in ka badan toban sano.Ilaa hadda, shirkaddu waxay cilmi-baadhis qoto-dheer ku samaysay in ka badan 100 nooc oo ah dawo-dhaqameedka Shiinaha ee inta badan la isticmaalo, waxaanay soo saartay kumannaan qaybood oo kiimiko ah.
Shirkaddu waxay leedahay shaqaale sare oo R & D ah iyo qalab tijaabo iyo falanqayn sax ah oo ku jira warshadaha, waxayna u adeegtay boqolaal machadyo cilmi baaris cilmiyeed.Waxay si dhakhso ah oo hufan u dabooli kartaa baahida macaamiisha
Kala-saar Xumo-xumo Daroogada, Diyaarinta iyo Adeegga Xaqiijinta Qaab-dhismeedka
Wasakhda daroogooyinka waxay si dhow ula xiriiraan tayada, badbaadada iyo xasiloonida daroogada.Xaqiijinta diyaarinta iyo qaab dhismeedka wasakhda daroogooyinka waxay naga caawin kartaa inaan fahamno hababka wasakhda iyo bixinta aasaaska hagaajinta habka wax soo saarka.Sidaa darteed, diyaarinta iyo kala-soocidda wasakhdu waxay muhiimad weyn u leedahay cilmi-baarista iyo horumarinta daroogada.
Si kastaba ha ahaatee, waxa ku jira wasakhda daawadu way yar tahay, isha waa ballaadhan tahay, qaab-dhismeedkuna inta badan wuxuu la mid yahay qaybta ugu muhiimsan.Tignoolajiyada noocee ah ayaa loo isticmaali karaa in lagu kala saaro oo lagu nadiifiyo dhammaan wasakhda daawada mid mid iyo si degdeg ah?Waa maxay farsamooyinka iyo hababka loo isticmaalo si loo xaqiijiyo dhismaha wasakhdaas?Tani waa dhibka iyo caqabada ay la kulmaan qaybo badan oo dawooyin ah, gaar ahaan shirkadaha dawooyinka ee dawooyinka dhirta iyo daawaynta patent-ka Shiinaha.
Iyada oo ku saleysan baahiyaha noocaas ah, shirkaddu waxay bilawday adeegyada kala soocida wasakhda iyo nadiifinta daroogada.Ku tiirsanaanta nukliyeerka magnetic nukliyeerka, spectrometry mass iyo qalabka kale iyo teknoolajiyada, shirkaddu waxay si dhakhso ah u aqoonsan kartaa qaab-dhismeedka xeryahooda kala go'ay, si loo daboolo baahiyaha macaamiisha.
Tijaabada Xayawaanka ee SPF
Bedka dhismaha ee goobta tijaabada xayawaanku waa 1500 mitir oo laba jibbaaran, oo ay ku jiraan 400 mitir oo laba jibbaaran oo aag tijaabo ah oo heerka SPF ah iyo 100 mitir oo laba jibbaaran oo ah shaybaadhka unugyada heerka P2.Oo ay hogaaminayaan saynisyahano ka tirsan Jaamacadda Pharmaceutical ee Shiinaha, waxay samaysaa koox farsamo oo xudun u ah tiro dad ah oo soo noqday.Bixi noocyo xayawaan oo tayo sare leh, naqshadeynta tijaabada, mashaariicda guud iyo adeegyada kale ee cilmi-baarista cilmiga noolaha, barida iyo horumarinta warshadaha.
Baaxadda Ganacsiga
1. quudinta xoolaha yar
2. Qaabaynta cudurada xoolaha
3. Dib-u-soo-saarka mashruuca kulliyadda
4. Qiimaynta Pharmacodynamic in vivo
5. Qiimaynta farmashiyaha
6. Adeegga tijaabada unugyada burada
Awoodeena
1. Diirada saar tijaabooyinka dhabta ah
2. Si adag u habeeyaan habka
3. Si adag u saxiix heshiiska sirta
4. Shaybaadh u gaar ah oo aan lahayn xiriiriye dhexdhexaad ah
5. Kooxda farsamada ee xirfadlayaasha ah ayaa dammaanad qaadaya tayada tijaabada ah
Deegaanka tijaabada SPF, quudinta qofka si gaar ah loo xilsaaray, la socodka wakhtiga dhabta ah ee horumarka tijaabada ah
