Orientin
Codsiga Orientin
Orientin waa flavonoid bioactive ah oo si dabiici ah u soo baxa oo leh astaamo bayooloji oo kala duwan, oo ay ku jiraan anti-bararka, antioxidant, anti-buro, ilaalinta wadnaha iyo wixii la mid ah.Orientin waa wakiil neuroprotective ah oo rajo leh, kaas oo ku habboon daaweynta xanuunka neuropathic.
Bioactivity ee Orientin
Sharaxaad:Orientin waa flavonoids bioactive ah oo si dabiici ah u soo baxa oo leh astaamo bayooloji oo kala duwan, oo ay ku jiraan anti-bararka, antioxidant, anti-buro, ilaalinta wadnaha iyo wixii la mid ah.Orientin waa wakiil neuroprotective ah oo rajo leh, kaas oo ku habboon daaweynta xanuunka neuropathic.
Qaybaha la xidhiidha:goobta cilmi-baarista > > kansarka
Jidka ishaarada > > kale >> kale
Goobta cilmi-baarista > Cudurrada neerfaha
Rdareen:[1]Dhakal H, iyo al.Saamaynta xannibaadda ee orientin ee bararka xasaasiyadda ee unugga mastarada.Pharmacol Rep. 2020 Jan 24.
[2].Guo D, iyo al.Orientin iyo xanuunka neuropathic ee jiirka oo leh xididdada dareemayaasha laf-dhabarka.61Int Immunopharmacol.2018 Meey;58:72-79.
Sifooyinka physicochemical ee Orientin
Cufnaanta: 1.8 ± 0.1 g / cm3
Barta karkarinta: 816.1 ± 65.0 ° C at 760 mmHg
Meesha dhalaalka: 260-285 º C
Qaacidada molecular: C21H20O11
Miisaanka Molecular: 448.377
Barta Tooshka ah: 289.1 ± 27.8 ° C
Tirada saxda ah: 448.100555
PSA: 201.28000
LogP: 1.58
Muuqaalka: budada jaalaha ah
Cadaadiska uumiga: 0.0 ± 3.1 mmHg at 25 ° C
Tusmada dib-u-celinta: 1.767
Biyo- milmi kara: 1 M
NaOH: milmaya 1mg/ml, cad, oranji huruud ah
Macluumaadka badbaadada Digitalis
Bayaanka Badbaadada (Yurub): 24/25
Xeerka gaadiidka ee alaabta khatarta ah: noh ee dhammaan noocyada gaadiidkaRTECS号:DJ3009300
Dib u eegista suugaanta Orientin
Kala soocida lamaanaha isomer ee C-glycosylflavone isomer orientin/isoorientin iyo vitexin/isovitexin iyadoo la adeegsanayo HPLC-MS cabirka saxda ah ee tirada iyo CID-da.
PhytochemDabada.16 (5), 295-301, (2005)
HPLC-MS iyadoo la adeegsanayo isku-dhac ay keentay kala-bax (CID) ayaa loo isticmaalay aqoonsiga lammaanaha C-glycosylflavone isomer orientin/isoorientin iyo vitexin/isovitexin.HPLC-CID/MS waxa ay falanqaysaa prod.
Saamaynta ka-hortagga dhiig-karka iyo wadnaha ee miraha Lagenaria siceraria ee NG-nitro-L-arginine methyl ester (L-NAME) ayaa sababay jiirka hypertensive.
FarmashiyahaBiyo.50 (11), 1428-35, (2012)
Lagenaria siceraria (Molina) Standl.(Cucurbitacae) (LS) ayaa lagu soo warramey inay leedahay waxqabadyo ka hortag ah wadnaha, dhiig-karka, iyo duritaanka.
Horumarinta iyo ansixinta habka HPTLC ee tirada isku mar ah ee isoorientin, isovitexin, orientin, iyo vitexin ee flavonoids-caleen bamboo.
J. AOAC Int.93 (5), 1376-83, (2010)
Hab fudud oo HPTLC ah ayaa loo sameeyay go'aaminta isku mar ee isoorientin, isovitexin, orientin, iyo vitxin, labadaba saafi ah iyo muunado ganacsi oo ah flavonoids-caleen bamboo.Flavon-ka...
Ingriiska oo loo yaqaan Orientin
(1S)-1,5-Anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-D-glucitol
2- (3,4-Dihydroxyphenyl) -5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran- 2-yl] -4H-chromen-4-kow
Orientin 8-C-β-D-glucopyranoside
3',4',5,7-tetrahydroxyflavone-8-C-glucoside
2- (3,4-Dihydroxyphenyl) -5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran- 2-yl] -4H-chromen-4-on
Luteolin-8-C-glucoside
3',4',5,7-tetrahydroxyflavone 8-glucoside
4H-1-Benzopyran-4-kow, 2- (3,4-dihydroxyphenyl) -8-β-D-glucopyranosyl-5,7-dihydroxy-
D-Glucitol, 1,5-anhydro-1-C-[2- (3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-8-yl]-, (1S) -
Orientin
lutexin
2- (3,4-Dihydroxyphenyl) -5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran- 2-yl] -4H-chromen-4-kow
2- (3,4-Dihydroxyphenyl)-8-bD-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-kow
