Synephrine
Isticmaalka Synephrine
Synephrine (oxedrine) waxaa laga soo qaatay dhirta liinta α- Adrenergic iyo β- Adrenergic agonists waxay leeyihiin isku mid ah oo isku mid ah iyo qaabdhismeedka ephedra iyo ephedrine alkaloids.
Magaca Synephrine
Magaca Ingiriisiga: synephrine
Shiineeska loo yaqaan: deoxyepinephrine |simforine |DL deoxyepinephrine |1-p-hydroxyphenyl-2-methylaminoethanol |cinephrine |1 - (4-hydroxyphenyl) - 2 - (methylamino) ethanol
Bioactivity ee Synephrine
Sharaxaada: synephrine (oxedrine) waxaa laga soo qaatay dhirta liinta α- Adrenergic iyo β- Adrenergic agonists waxay leeyihiin isku mid ah qaab-dhismeedka ephedra iyo ephedrine alkaloids.
Qaybaha khuseeya: α- adrenergic iyo β-adrenergic[1]
Daraasadda Vivo: adrenaline (1mg / kg; gavage afka; soconaysa 8 maalmood; PVL iyo jiirka BDL) waxay si weyn u wanaajisay xaaladda hyperkinetic ee PVL iyo jiirka BDL.Jiirka PVL iyo BDL waxay si weyn hoos ugu dhigeen cadaadiska xididdada xididka, xididka xididka xididka qulqulka qulqulka dhiigga iyo tusmada wadnaha, halka daawaynta adrenaline ay kordhisay cadaadiska celceliska halbowlaha iyo iska caabinta xididdada xididdada iyo xididdada [2].Qaabka xayawaanka: Jiirka leh xididka xididka xididka (PVL) ama xadhkaha xuubka xuubka (BDL) [2] qiyaasta: 1 mg / kg 12 saacadood kasta: gavage afka;Natiijooyinka maalinta 8: PVL iyo jiirka BDL ayaa si weyn hoos ugu dhacay cadaadiska xididdada xididka, qulqulka dhiigga ee laanta portal iyo tusmada wadnaha, oo kordhay celceliska cadaadiska halbowlaha iyo iska caabinta nidaamka iyo xididka portal
Tixraacyada: 1] Thomas JE, iyo al.STEMI ee nin 24-sano jir ah ka dib markii la isticmaalo kabka cuntada ee synephrine-ka kooban: warbixin kiis iyo dib u eegis suugaanta.Tex Wadnaha Inst J. 2009;36 (6): 586-90.
[2].Huang YT, iyo al.Saamaynta hemodynamic ee daaweynta synephrine ee jiirka hypertensive portal.Jpn J Pharmacol.2001 Feb;85 (2): 183-8.
Sifooyinka Kiimikaad ee Simephrine
Cufnaanta: 1.2 ± 0.1 g / cm3
Barta karkarinta: 341.1 ± 27.0 ° C at 760 mmHg
Meesha dhalaalka: 187 ° C (Dec.) ( shidan)
Qaacidada unugyada: C9H13NO2
Miisaanka Molecular: 167.205
Barta iftiimaya: 163.4 ± 14.3 ° C
Tirada saxda ah: 167.094635
PSA: 52.49000
LogP:-0.03
Muuqaalka: caddaan ilaa budada beige
Cadaadiska Uumiga: 0.0 ± 0.8 mmHg at 25 ° C
Tusmada dib-u-celinta: 1.572
Xaaladaha Kaydinta: Alaabtan waa in la xidhaa oo la kaydiyaa.
Macluumaadka Badbaadada ee Synflynn
Astaanta: ghs07
Erayga calaamad: digniin
Hadalka halista: h315-h319-h335
Bayaanka digniinta: p261-p305 + P351 + P338
Qalabka ilaalinta shakhsi ahaaneed: maaskaro boodhka nooca N95 (US);indho-shareer;Gacan-gashiyada
Koodhka halista (Yurub): Xi: iritant;
Bayaanka khatarta ah (Yurub): R36 / 37/38
Bayaanka badbaadada (Yurub): s26-s36
Xeerka gaadiidka ee alaabta khatarta ah: noh ee dhammaan noocyada gaadiidka
RTECS No.: do7350000
Xeerka Kastamka: 2922199090
Diyaarinta Synephrine
Natiijooyinka liinta aurantium L.
Kastamka Synephrine
Xeerka Kastamka: 29225090
Dulmarka Shiinaha: 29225090 Amino alkohol phenols kale, phenols amino acids iyo xeryahooda kale ee amino oksijiin heerka VAT: 17.0% Heerka dhimista cashuurta: 13.0% Shuruudaha sharciyeynta: ab.Tacriifada MFN: 6.5% Qiimaha guud: 30.0%
Qodobbada ku dhawaaqida: magaca badeecada, halabuurka, nuxurka, ujeedada, chroma of ethanolamine iyo milixdeeda waa in la soo sheegaa, baakadaha ethanolamine iyo milixdeeda waa in la soo sheegaa.
Shuruudaha kormeerka: A. Foomka fasaxa kastamka ee Alaabta soo gasha B. foomka banaynta kastamka ee alaabta dibadda
Kormeerka iyo karantiilka: R. kormeerka fayadhowrka iyo kormeerida cuntada dibadda laga keeno S. ilaalinta fayadhowrka iyo kormeerida cuntada la dhoofiyo
Soo koobid:2922509090.amino-alcohol-phenols, amino-acid-phenols iyo amino-compounds kale oo leh shaqada oksijiinta.VAT: 17.0%.Heerka dhimista canshuurta: 13.0%..Qiimaha MFN:6.5%.Qiimaha guud: 30.0%
Suugaanta Synephrine
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Brazil waxaa loo arkaa mid ka mid ah wadamada leh tirada ugu badan ee isticmaala nooca amphetamine-ka (ATS) ee adduunka oo dhan, gaar ahaan diethylpropion (DIE) iyo fenproporex (FEN).Isticmaalka ATS inta badan waa linke.
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Magaca Ingiriisida ee Synephrine
Synefrin
Simpatol
EINECS 202-300-9
4-[(1R) -1-Hydroxy-2-(methylamino) ethyl] phenol
(-)-Oxedrine
Oxedrine
(-) Calaamadaha
(R) -4- (1-hydroxy-2- (methylamino) ethyl) phenol
1- (4-Hydroxyphenyl) -2-methylaminoethanol
Synephrin
Ethaphene
Analeptin
Simpalon
(-)-Synephrine
Benzenemethanol, 4-hydroxy-α-[(methylamino)methyl]-, (αR)
Synephrine
MFCD00002370
D-Synephrine
(-)-4-hydroxy-α-[(methylamino)methyl]benzenemethanol
Sympathol
Pentedrin
(-)-p-hydroxy-α-[(methylamino)methyl] khamriga benzyl
