Vitexin;Apigenin8-C-glucoside CAS No. 3681-93-4
Macluumaadka Muhiimka ah
Magaciisa:apigenin8-c-glucoside
Magaca kiimikada:8- β- D-glucopyranosyl-5,7-dihydroxy-2- (4-hydroxyphenyl) -4H-1-benzopyran-4-hal
Qaaciidada molecular:c21h20o10 dhoola cadeynta canonical: C1 = CC (= CC = C1C2 = CC (= O) C3 = C (O2) C (= C (C = C3O) o) C4C (C (C (O4) co) o) o) o
Miisaanka molecular:432.3775
Lambarka CAS:3681-93-4
Tilmaamaha Jirka iyo Kiimikada
Muuqashada:budo jaale ah
Xigasho:Craeagus pinnatifida, geedka Rosaceae, wuxuu leeyahay miro qalalan oo qaan gaar ah.
Codsiga
Sidaa darteed, alaabta ceeriin ee caleemaha Vitex saafiga ah iyo miraha Vitex ayaa ah kuwo aad u yar, caleemaha Vitex ee la soo ururiyey ayaa asal ahaan loo isticmaalaa in lagu nadiifiyo oo lagu nadiifiyo saliidda Vitex, taas oo horseedaysa soo-saarayaasha dhirta in ay ka tanaasulaan aasaaska oo ay soo saaraan Vitexin.Taa baddalkeeda, waxay isticmaalaan caleemaha hawthorn si ay u soo saaraan Vitexin, ka soo saaraan Vitexin wadarta guud ee flavonoids ee Hawthorn Leaves iyada oo loo marayo soo saarista, kala-soocidda, nadiifinta iyo hababka kale, iyo ugu dambeyntii samaynta diyaargarowga qallalan.
Vitexin waxaa inta badan loo isticmaalaa in lagu daweeyo cudurrada wadnaha iyo xididdada dhiigga.Nadiifinta Vitexin guud ahaan waxaa looga baahan yahay inay ahaato> 98% (HPLC).Vitexin ee duritaanka ayaa loo isticmaalay daawada kiliinikada.Hawlaha ugu muhiimsan ee Vitexin waa kor u qaadista wareegga dhiigga iyo ka saarista fadhiidnimada dhiigga, nidaaminta qi iyo garaacista garaaca wadnaha.Waxa loo isticmaalaa xannibaadda laabta oo ay keento fadhiista dhiigga.Calaamadaha waxaa ka mid ah laabta oo adkaata, neef-qabatin, xiirid aagga hore ee wadnaha, garaaca wadnaha, hilmaan, dawakhaad iyo tinnitus.Wadnaha wadnaha, angina pectoris, hyperlipidemia, dhiig-yarida halbowlaha wadnaha iyo calaamado kale.
Cudurada ku dhaca wadnaha iyo xididada xididada xididada xididada xididada xididada xididada dhiiga qaada ayaa ah xanuunada ugu badan ee ku dhaca bini aadamka,waxana ay noqdeen kuwa ugu badan ee u geeriyooda aduunka.Marka loo eego qiyaasaha WHO, cudurrada wadnaha iyo xididdada dhiigga waxay sababaan ugu yaraan 12 milyan oo dhimasho adduunka ah sannad kasta, waxayna noqdeen cadowga koowaad ee caafimaadka aadanaha.Dhacdooyinka sare iyo dhimashada cudurada wadnaha ayaa haga jihada daroogada R & D iyo wax soo saarka.Daawooyinka wadnaha iyo xididada xididada dhiigga ayaa 4 ka mid ah 10-ka dawo ee ugu iibka badan adduunka sannadkii 2005. Waxaa jira noocyo badan oo dawooyinka patent-ka Shiinaha loogu talagalay daaweynta cudurrada wadnaha, laakiin ma jiraan wax ka badan saddex nooc (Fuzheng Ningxin, aromatic Wentong , kor u qaadida wareegga dhiigga iyo ka saarida fadhiidnimada dhiigga).Laga soo bilaabo xaaladda iibka ee suuqa tafaariiqda, Vitexin iyo dawooyinka kale ee kor u qaadida wareegga dhiigga iyo ka saarida stasis dhiig waxay leeyihiin xaalad iib oo wanaagsan.Waa mid ka mid ah dawooyinka korriinka ugu dhaqsaha badan leh.Suuqa si degdeg ah ayuu u fidayaa, waxa uu leeyahay awood weyn, awood suuqeed oo ballaadhan iyo meel tartan oo ballaadhan.
Vitexin sidoo kale waa qayb ka mid ah dawooyinka dabiiciga ah ee ka hortagga kansarka iyo kansarka.Foreign Diaz ayaa sheegay in flavonoids laga helay Vitex negundo, sida Vitexin, ay muujisay cytotoxicity ballaaran unugyada kansarka aadanaha ee bioassay;Massateru iyo al.Waxaa la ogaaday in bauhinin uu joojiyay koritaanka unugyada kansarka sanbabada bini'aadamka (PC-12) iyo unugyada kansarka mindhicirka ee bini'aadamka (HCT116) ee baaritaanka MTT.
Qaar badan oo ka mid ah soo saarayaasha dhirta ayaa soo saaraya dhirta Vitexin.Marka lagu daro soosaarka Vitexin, sida soosaarka Vitexin iyo laga soosaaray hawthorn, dhammaantood waxay soo saaraan Vitexin oo ah tusaha qaybta waxtarka leh, badeecadaha sidoo kale waxaa laga iibiyaa macaamiisha leh Vitexin sida index.Tusmada nuxurka ee Vitexin ee laga soosaaray Vitex iyo hawthorn asal ahaan waa qiyaastii 5%.
Waxaan aaminsanahay inaad sidoo kale aragtay warbixino isku mid ah oo ku saabsan kansarka ka hortagga kansarka iyo kansarka Hawthorn: cilmi-baaris dhowaan la sameeyay ayaa lagu ogaaday in Hawthorn ay ku jirto xarun la yiraahdo Vitexin, taas oo leh saameynta kansarka ka hortagga.Nitrosamine iyo aflatoxin waxay keeni karaan kaansarka habka dheefshiidka ama ka sii daraan.Daraasadaha tijaabada ah ayaa muujinaya in laga soosaaray hawthorn aysan kaliya xannibi karin isku-darka nitrosamine, laakiin sidoo kale waxay joojinayaan saameynta kansarka ee aflatoxin.Sidaa darteed, dadka khatarta sare ugu jira kansarka mindhicirka waa inay badanaa cunaan hawthorn.Bukaannada qaba kansarka, Hawthorn iyo bariiska ayaa sidoo kale loo isticmaali karaa in lagu kariyo boorash si wadajir ah haddii ay dhacdo dyspepsia, taas oo aan caawin karin oo kaliya dheefshiidka, laakiin sidoo kale waxay ka ciyaaraan door caawiye ah ka hortagga kansarka.
Maaddooyinka kiimikaad ee Vitexin ee Hawthorn aad ayay uga yar yihiin ta Vitexin, laakiin sababta oo ah dad yar ayaa si dhab ah u yaqaan oo fahmaya Vitexin si ay u taajiraan, saamaynta kansarka iyo ka hortagga kansarka ee Vitexin ayaa lagu xidhay buuraha!
